ES8306118A1 - "procedimiento para la preparacion de una sulfonilurea". - Google Patents
"procedimiento para la preparacion de una sulfonilurea".Info
- Publication number
- ES8306118A1 ES8306118A1 ES515399A ES515399A ES8306118A1 ES 8306118 A1 ES8306118 A1 ES 8306118A1 ES 515399 A ES515399 A ES 515399A ES 515399 A ES515399 A ES 515399A ES 8306118 A1 ES8306118 A1 ES 8306118A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- atoms
- pharmaceutical compositions
- compositions containing
- sulfonyl ureas
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Endocrinology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE SULFONILUREAS Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE Y ES ALCOHILENO C <- ; R ES ALCOHILO C <- ; R ES HIDROGENO, CLORO O METILO; Y R PUEDE SER UNO DE VARIOS RADICALES. CONSISTE EN LA REACCION DE HALOGENUROS DE BENZOSULFONILO ADECUADAMENTE SUSTITUIDOS CON UREAS SUSTITUIDAS CON R O CON SUS SALES DE METALES ALCALINOS, EN PRESENCIA O AUSENCIA DE UN DISOLVENTE INERTE, A LA TEMPERATURA AMBIENTE O SUPERIOR. TAMBIEN SE PUEDEN HACER REACCIONAR HALOGENUROS DE ACIDOS BENZOSULFINICOS, O SUS SALES DE METALES ALCALINOS, CON N-R -N -HIDROXIUREA. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SUS PROPIEDADES HIPOGLUCEMICAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19813134780 DE3134780A1 (de) | 1981-09-02 | 1981-09-02 | "sulfonylharnstoffe, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung" |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8306118A1 true ES8306118A1 (es) | 1983-05-01 |
| ES515399A0 ES515399A0 (es) | 1983-05-01 |
Family
ID=6140704
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES515397A Granted ES515397A0 (es) | 1981-09-02 | 1982-08-31 | "procedimiento para la preparacion de una sulfonilurea". |
| ES515395A Expired ES8306114A1 (es) | 1981-09-02 | 1982-08-31 | "procedimiento para la preparacion de una sulfonilurea". |
| ES515396A Expired ES8306115A1 (es) | 1981-09-02 | 1982-08-31 | "procedimiento para la preparacion de una sulfonilurea". |
| ES515399A Granted ES515399A0 (es) | 1981-09-02 | 1982-08-31 | "procedimiento para la preparacion de una sulfonilurea". |
| ES515398A Granted ES515398A0 (es) | 1981-09-02 | 1982-08-31 | "procedimiento para la preparacion de una sulfonilurea". |
| ES515384A Granted ES515384A0 (es) | 1981-09-02 | 1982-08-31 | "procedimiento para la preparacion de una solfonilurea". |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES515397A Granted ES515397A0 (es) | 1981-09-02 | 1982-08-31 | "procedimiento para la preparacion de una sulfonilurea". |
| ES515395A Expired ES8306114A1 (es) | 1981-09-02 | 1982-08-31 | "procedimiento para la preparacion de una sulfonilurea". |
| ES515396A Expired ES8306115A1 (es) | 1981-09-02 | 1982-08-31 | "procedimiento para la preparacion de una sulfonilurea". |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES515398A Granted ES515398A0 (es) | 1981-09-02 | 1982-08-31 | "procedimiento para la preparacion de una sulfonilurea". |
| ES515384A Granted ES515384A0 (es) | 1981-09-02 | 1982-08-31 | "procedimiento para la preparacion de una solfonilurea". |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4542139A (es) |
| EP (1) | EP0073507B1 (es) |
| JP (1) | JPS5846068A (es) |
| KR (1) | KR880002706B1 (es) |
| AT (1) | ATE16102T1 (es) |
| AU (1) | AU558339B2 (es) |
| CA (1) | CA1193603A (es) |
| DE (2) | DE3134780A1 (es) |
| DK (1) | DK391982A (es) |
| ES (6) | ES515397A0 (es) |
| FI (1) | FI76567C (es) |
| GR (1) | GR76895B (es) |
| HU (1) | HU188805B (es) |
| IL (1) | IL66697A0 (es) |
| MX (1) | MX154808A (es) |
| NO (1) | NO822940L (es) |
| NZ (1) | NZ201768A (es) |
| PH (1) | PH18218A (es) |
| PT (1) | PT75492B (es) |
| ZA (1) | ZA826391B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3210063A1 (de) * | 1982-03-19 | 1983-09-22 | Hoechst Ag, 6230 Frankfurt | Sulfonylharnstoffe, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung |
| SE9201076L (sv) * | 1992-04-06 | 1993-10-07 | Shimon Slavin | Användningen av gamla läkemedel för behandling av diabetes |
| US5681832A (en) * | 1995-02-17 | 1997-10-28 | The United States Of America As Represented By The Department Of Health And Human Services | Aroylaniline compounds, pharmaceutical compositions, and methods of using same to inhibit viral activity |
| JP2000256323A (ja) * | 1999-01-08 | 2000-09-19 | Japan Tobacco Inc | ２−オキソキノリン化合物及びその医薬用途 |
| PT1357111E (pt) * | 2000-12-28 | 2009-10-20 | Shionogi & Co | Derivados de 2-piridona com afinidade para receptores de canabinóides do tipo 2 |
| ATE540034T1 (de) * | 2005-11-03 | 2012-01-15 | Portola Pharm Inc | Ä4-(6-halo-7-substituierte-2,4-dioxo-1,4-dihydr - 2h-chinazolin-3-yl)-phenylü-5-chloro-thiophen-2 yl-sulfonylharnstoffe und relevante formen und verfahren |
| CN101720324A (zh) * | 2007-05-02 | 2010-06-02 | 波托拉医药品公司 | [4-(6-氟-7-甲基氨基-2,4-二氧代-1,4-二氢-2h-喹唑啉-3-基)-苯基]-5-氯-噻吩-2-基-磺酰基脲盐、其相关的形式和方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3819633A (en) * | 1970-04-01 | 1974-06-25 | Erba Carlo Spa | (iso)quinolyl sulfonylureas having antidiabetic activity |
| AT357560B (de) * | 1976-05-18 | 1980-07-25 | Hoechst Ag | Verfahren zur herstellung von neuen (1,2- dihydro-2-oxo-nicotinamido)-alkylbenzolsul- fonylharnstoffen und von deren salzen |
| DE2621958A1 (de) * | 1976-05-18 | 1977-12-08 | Hoechst Ag | Benzolsulfonylharnstoffe und verfahren zu ihrer herstellung |
| MTP848B (en) * | 1978-06-27 | 1980-06-24 | Hoechst Ag | Sulfonyl ureas process for their manufacture pharmaceutical preparation on the basis of there compounds and their use |
| DE2948434A1 (de) * | 1979-12-01 | 1981-06-11 | Hoechst Ag, 6000 Frankfurt | 1-piperidinsulfonylharnstoffe und verfahren zu ihrer herstellung |
| DE2951135A1 (de) * | 1979-12-19 | 1981-06-25 | Hoechst Ag, 6230 Frankfurt | Sulfonylharnstoffe, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung |
-
1981
- 1981-09-02 DE DE19813134780 patent/DE3134780A1/de not_active Withdrawn
-
1982
- 1982-08-28 AT AT82107938T patent/ATE16102T1/de not_active IP Right Cessation
- 1982-08-28 EP EP82107938A patent/EP0073507B1/de not_active Expired
- 1982-08-28 DE DE8282107938T patent/DE3266953D1/de not_active Expired
- 1982-08-31 ES ES515397A patent/ES515397A0/es active Granted
- 1982-08-31 NO NO822940A patent/NO822940L/no unknown
- 1982-08-31 NZ NZ201768A patent/NZ201768A/en unknown
- 1982-08-31 MX MX7875A patent/MX154808A/es unknown
- 1982-08-31 ES ES515395A patent/ES8306114A1/es not_active Expired
- 1982-08-31 KR KR8203918A patent/KR880002706B1/ko active
- 1982-08-31 FI FI823007A patent/FI76567C/fi not_active IP Right Cessation
- 1982-08-31 ES ES515396A patent/ES8306115A1/es not_active Expired
- 1982-08-31 GR GR69173A patent/GR76895B/el unknown
- 1982-08-31 ES ES515399A patent/ES515399A0/es active Granted
- 1982-08-31 ES ES515398A patent/ES515398A0/es active Granted
- 1982-08-31 ES ES515384A patent/ES515384A0/es active Granted
- 1982-08-31 PH PH27799A patent/PH18218A/en unknown
- 1982-09-01 AU AU87892/82A patent/AU558339B2/en not_active Ceased
- 1982-09-01 HU HU822814A patent/HU188805B/hu unknown
- 1982-09-01 PT PT75492A patent/PT75492B/pt unknown
- 1982-09-01 DK DK391982A patent/DK391982A/da not_active Application Discontinuation
- 1982-09-01 JP JP57150810A patent/JPS5846068A/ja active Pending
- 1982-09-01 ZA ZA826391A patent/ZA826391B/xx unknown
- 1982-09-01 IL IL66697A patent/IL66697A0/xx unknown
- 1982-09-01 CA CA000410586A patent/CA1193603A/en not_active Expired
-
1984
- 1984-04-26 US US06/603,987 patent/US4542139A/en not_active Expired - Fee Related
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