ES8304570A1 - Procedimiento para la obtencion de 5-diazacicloalquil-imidazo(2,1-b) (1,3,5) benzotiadiazepinas. - Google Patents
Procedimiento para la obtencion de 5-diazacicloalquil-imidazo(2,1-b) (1,3,5) benzotiadiazepinas.Info
- Publication number
- ES8304570A1 ES8304570A1 ES513638A ES513638A ES8304570A1 ES 8304570 A1 ES8304570 A1 ES 8304570A1 ES 513638 A ES513638 A ES 513638A ES 513638 A ES513638 A ES 513638A ES 8304570 A1 ES8304570 A1 ES 8304570A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- halogeno
- sulfamoyl
- hydrogen
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Polymerisation Methods In General (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE 5-DIAZACICLOALQUIL-IMIDAZO 2,1-B 1,3,5 BENZOTIADIAZEPINAS, ASI COMO DE SUS N- Y/O S-OXIDOS, DERIVADOS CUATERNARIOS DE ALQUILO INFERIOR Y SALES, DE FORMULA (I), EN LA QUE PH ES 1,2-FENILENO SUSTITUIDO O SIN SUSTITUIR; R, R Y R PUEDEN SER VARIOS TIPOS DE RADICALES; Y C<MH <M Y C<NH <N SON ALQUILENO C <- . CONSISTE EN LA REACCION DE CIERRE DE ANILLO, BAJO CONDICIONES DESHIDRATANTES O DESHIDROSULFURANTES, DE UN COMPUESTO DE FORMULA (II), EN LA QUE Z ES OXIGENO, AZUFRE O NH; Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE EFECTUA EN UN DISOLVENTE INERTE, EN PRESENCIA DE HALUROS Y/O OXIHALUROS DE FOSFORO O HALUROS DE CIANO. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SUS PROPIEDADES NEUROLEPTICAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15867180A | 1980-06-12 | 1980-06-12 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES513638A0 ES513638A0 (es) | 1983-03-01 |
| ES8304570A1 true ES8304570A1 (es) | 1983-05-16 |
Family
ID=22569177
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES502949A Granted ES502949A0 (es) | 1980-06-12 | 1981-06-11 | Procedimiento para la obtencion de nuevas 5-diazacicloalquil-imidazo (2,1-b)(1,3,5) benzotiadiazepinas |
| ES513638A Expired ES8304570A1 (es) | 1980-06-12 | 1982-07-01 | Procedimiento para la obtencion de 5-diazacicloalquil-imidazo(2,1-b) (1,3,5) benzotiadiazepinas. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES502949A Granted ES502949A0 (es) | 1980-06-12 | 1981-06-11 | Procedimiento para la obtencion de nuevas 5-diazacicloalquil-imidazo (2,1-b)(1,3,5) benzotiadiazepinas |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0042354B1 (es) |
| JP (1) | JPS57118589A (es) |
| KR (2) | KR840002145B1 (es) |
| AT (1) | ATE16935T1 (es) |
| AU (1) | AU538864B2 (es) |
| CA (1) | CA1163630A (es) |
| DD (1) | DD160535A5 (es) |
| DE (1) | DE3173184D1 (es) |
| DK (1) | DK255281A (es) |
| ES (2) | ES502949A0 (es) |
| FI (1) | FI69310C (es) |
| GB (1) | GB2077727B (es) |
| GR (1) | GR78222B (es) |
| HU (1) | HU185128B (es) |
| IE (1) | IE52043B1 (es) |
| IL (1) | IL63079A (es) |
| NO (1) | NO811977L (es) |
| NZ (1) | NZ197392A (es) |
| PT (1) | PT73173B (es) |
| ZA (1) | ZA813930B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4459232A (en) * | 1981-12-07 | 1984-07-10 | Ciba-Geigy Corporation | Imidazo[1,2-c][1,3]benzodiazepines |
| FI824170L (fi) * | 1981-12-07 | 1983-06-08 | Ciba Geigy Ag | Imidazobensodiazepiner, foerfarande foer deras framstaellning, dessa foereningar innehaollande farmaceutiska preparat och deras anvaendning |
| US4460587A (en) * | 1981-12-07 | 1984-07-17 | Ciba-Geigy Corporation | 5-Diazacycloalkyl imidazo[1,2-c][1,3]benzodiazepines |
| US4507311A (en) * | 1981-12-07 | 1985-03-26 | Ciba-Geigy Corporation | Imidazo[1,2-c][1,3]benzodiazepines |
| US4460508A (en) * | 1981-12-07 | 1984-07-17 | Ciba-Geigy Corporation | 5-Diazacycloalkylimidazo[1,2-c][1,3]benzodiazepines |
| US4595535A (en) * | 1983-06-06 | 1986-06-17 | Ciba-Geigy Corporation | Diazacycloalkyl-1,2,4-triazolo[2,3-c][1,3]benzodiazepines useful as neuroleptic and/or antihistaminic agents |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2349064A1 (de) * | 1973-09-29 | 1975-04-10 | Basf Ag | 1,3-diazacycloalkeno- eckige klammer auf 1,2-d eckige klammer zu -benzo- eckige klammer auf f eckige klammer zu -1,3,4- thiadiazepine |
| IT7851496A0 (it) * | 1977-10-31 | 1978-10-13 | Sandoz Ag | Menti pirazinobenzossazepine loro preparazione e loro impiego quali medica |
-
1981
- 1981-05-30 JP JP56083705A patent/JPS57118589A/ja active Pending
- 1981-06-08 FI FI811771A patent/FI69310C/fi not_active IP Right Cessation
- 1981-06-09 GB GB8117623A patent/GB2077727B/en not_active Expired
- 1981-06-09 DE DE8181810228T patent/DE3173184D1/de not_active Expired
- 1981-06-09 EP EP81810228A patent/EP0042354B1/de not_active Expired
- 1981-06-09 AT AT81810228T patent/ATE16935T1/de not_active IP Right Cessation
- 1981-06-10 GR GR65189A patent/GR78222B/el unknown
- 1981-06-10 CA CA000379490A patent/CA1163630A/en not_active Expired
- 1981-06-11 ZA ZA813930A patent/ZA813930B/xx unknown
- 1981-06-11 DD DD81230728A patent/DD160535A5/de unknown
- 1981-06-11 DK DK255281A patent/DK255281A/da not_active Application Discontinuation
- 1981-06-11 HU HU811736A patent/HU185128B/hu unknown
- 1981-06-11 NZ NZ197392A patent/NZ197392A/en unknown
- 1981-06-11 ES ES502949A patent/ES502949A0/es active Granted
- 1981-06-11 IL IL63079A patent/IL63079A/xx unknown
- 1981-06-11 IE IE1302/81A patent/IE52043B1/en unknown
- 1981-06-11 AU AU71641/81A patent/AU538864B2/en not_active Ceased
- 1981-06-11 NO NO811977A patent/NO811977L/no unknown
- 1981-06-11 PT PT73173A patent/PT73173B/pt unknown
- 1981-06-12 KR KR1019810002117A patent/KR840002145B1/ko active IP Right Grant
-
1982
- 1982-07-01 ES ES513638A patent/ES8304570A1/es not_active Expired
-
1984
- 1984-07-26 KR KR1019840004435A patent/KR850000614B1/ko active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CA1163630A (en) | 1984-03-13 |
| ES513638A0 (es) | 1983-03-01 |
| EP0042354A2 (de) | 1981-12-23 |
| AU538864B2 (en) | 1984-08-30 |
| ZA813930B (en) | 1982-06-30 |
| JPS57118589A (en) | 1982-07-23 |
| HU185128B (en) | 1984-12-28 |
| GB2077727A (en) | 1981-12-23 |
| EP0042354B1 (de) | 1985-12-11 |
| DE3173184D1 (en) | 1986-01-23 |
| ATE16935T1 (de) | 1985-12-15 |
| ES8300761A1 (es) | 1982-11-01 |
| GB2077727B (en) | 1984-03-07 |
| DK255281A (da) | 1981-12-13 |
| FI811771L (fi) | 1981-12-13 |
| IE811302L (en) | 1981-12-12 |
| FI69310C (fi) | 1986-01-10 |
| ES502949A0 (es) | 1982-11-01 |
| DD160535A5 (de) | 1983-09-07 |
| PT73173B (de) | 1983-04-29 |
| KR840002145B1 (ko) | 1984-11-23 |
| IE52043B1 (en) | 1987-05-27 |
| IL63079A0 (en) | 1981-09-13 |
| NO811977L (no) | 1981-12-14 |
| KR850000614B1 (ko) | 1985-05-01 |
| EP0042354A3 (en) | 1982-02-24 |
| IL63079A (en) | 1985-06-30 |
| GR78222B (es) | 1984-09-26 |
| NZ197392A (en) | 1984-03-30 |
| KR850001467A (ko) | 1985-03-18 |
| KR830006313A (ko) | 1983-09-20 |
| AU7164181A (en) | 1981-12-17 |
| FI69310B (fi) | 1985-09-30 |
| PT73173A (de) | 1981-07-01 |
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