ES8303429A1 - Procedimiento para la obtencion de compuestos del acido 7b-amino-tiadiazolilacetilamino-3-amoniometil-3-cefem-4-car-boxilico - Google Patents

Procedimiento para la obtencion de compuestos del acido 7b-amino-tiadiazolilacetilamino-3-amoniometil-3-cefem-4-car-boxilico

Info

Publication number
ES8303429A1
ES8303429A1 ES505409A ES505409A ES8303429A1 ES 8303429 A1 ES8303429 A1 ES 8303429A1 ES 505409 A ES505409 A ES 505409A ES 505409 A ES505409 A ES 505409A ES 8303429 A1 ES8303429 A1 ES 8303429A1
Authority
ES
Spain
Prior art keywords
denotes
group
preparation
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES505409A
Other languages
English (en)
Other versions
ES505409A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES505409A0 publication Critical patent/ES505409A0/es
Publication of ES8303429A1 publication Critical patent/ES8303429A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS DEL ACIDO 7~J-AMINOTIADIAZOLILACETILAMINO-3-AMONIOMETIL-3-CEFEM-4-CARBOXILICO Y DE SUS SALES DE FORMULA (I), EN LA QUE N VALE 0 O 1; AM ES AMINO; T ES UN GRUPO TIADIZOL CON LOS ENLACES EN LOS ATOMOS DE CARBONO; Y R Y R PUEDEN SER VARIOS RADICALES. CONSISTE EN LA REACCION DE AMIDIFICACION ENTRE UN COMPUESTO DE FORMULA (II), EN LA QUE X ES UN RESTO SUSTITUIBLE POR SUSTITUCION NUCLEOFILICA Y LOS GRUPOS FUNCIONALES ESTAN PROTEGIDOS, Y UNA AMINA TERCIARIA CORRESPONDIENTE AL GRUPO R . LA REACCION SE LLEVA A CABO EN AGUA O EN DISOLUCION ACUOORGANICA A UN PH ENTRE 3 Y 8. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO ANTIBIOTICOS ANTIBACTERIALES.
ES505409A 1980-09-12 1981-09-11 Procedimiento para la obtencion de compuestos del acido 7b-amino-tiadiazolilacetilamino-3-amoniometil-3-cefem-4-car-boxilico Expired ES8303429A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH688180 1980-09-12
CH296481 1981-05-07

Publications (2)

Publication Number Publication Date
ES505409A0 ES505409A0 (es) 1983-02-01
ES8303429A1 true ES8303429A1 (es) 1983-02-01

Family

ID=25691846

Family Applications (2)

Application Number Title Priority Date Filing Date
ES505409A Expired ES8303429A1 (es) 1980-09-12 1981-09-11 Procedimiento para la obtencion de compuestos del acido 7b-amino-tiadiazolilacetilamino-3-amoniometil-3-cefem-4-car-boxilico
ES515426A Granted ES515426A0 (es) 1980-09-12 1982-09-01 Procedimiento para la obtencion de compuestos del acido 7 b-aminotiadiazolilacetilamino-3-amoniometil-3-cefem-4-carboxilico.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES515426A Granted ES515426A0 (es) 1980-09-12 1982-09-01 Procedimiento para la obtencion de compuestos del acido 7 b-aminotiadiazolilacetilamino-3-amoniometil-3-cefem-4-carboxilico.

Country Status (12)

Country Link
EP (1) EP0047977A3 (es)
AU (1) AU7517181A (es)
DD (1) DD201906A5 (es)
DK (1) DK405881A (es)
ES (2) ES8303429A1 (es)
FI (1) FI812810L (es)
GR (1) GR78245B (es)
HU (1) HU185656B (es)
IL (1) IL63790A0 (es)
NO (1) NO813109L (es)
NZ (1) NZ198336A (es)
PT (1) PT73658B (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR75644B (es) * 1980-06-18 1984-08-02 Fujisawa Pharmaceutical Co
DE3279470D1 (en) * 1981-04-03 1989-04-06 Fujisawa Pharmaceutical Co New cephem compounds, processes for their preparation, pharmaceutical compositions containing them and their starting compounds
US4521413A (en) * 1981-09-14 1985-06-04 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4457929A (en) * 1982-03-29 1984-07-03 Bristol-Myers Company 3-Quaternary ammonium methyl)-substituted cephalosporin derivatives
DE3409431A1 (de) * 1983-10-08 1985-04-18 Hoechst Ag, 6230 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
CA1276929C (en) * 1984-04-09 1990-11-27 Masahisa Oka Cephalosporin antibacterial agents
CN86107947A (zh) * 1985-11-22 1987-05-27 藤沢药品工业株式会社 新的头孢烯化合物及其制备方法
CA1293719C (en) * 1986-09-22 1991-12-31 Takao Takaya Cephem compounds and processes for preparation thereof
GB8721016D0 (en) * 1987-09-07 1987-10-14 Fujisawa Pharmaceutical Co Cephem compounds
US5202315A (en) * 1989-05-11 1993-04-13 Lucky, Ltd. Cephalosporin compounds
JPH0741485A (ja) * 1993-07-30 1995-02-10 Katayama Seiyakushiyo:Kk セフェム誘導体およびそれを含有する抗菌剤
AU2002952355A0 (en) * 2002-10-30 2002-11-14 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
ATE368042T1 (de) * 2002-10-30 2007-08-15 Astellas Pharma Inc Cephemverbindungen
AR045768A1 (es) 2003-09-18 2005-11-09 Fujisawa Pharmaceutical Co Compuestos de cefem y sus sales farmaceuticamente aceptables
EP2077262A4 (en) * 2006-10-23 2011-12-28 Takeda Pharmaceutical IMINOPYRIDINE DERIVATIVES AND THEIR USE
US20110039892A1 (en) 2008-04-23 2011-02-17 Takeda Pharmaceutical Company Limited Iminopyridine derivative and use thereof
US8481569B2 (en) 2008-04-23 2013-07-09 Takeda Pharmaceutical Company Limited Iminopyridine derivatives and use thereof
EA028342B1 (ru) 2011-09-09 2017-11-30 Мерк Шарп И Доум Корп. Способы лечения пневмонии
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
AU2014227660B2 (en) 2013-03-15 2014-11-06 Merck Sharp & Dohme Llc Ceftolozane antibiotic compositions
US20140274991A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Ceftolozane pharmaceutical compositions
WO2015035376A2 (en) 2013-09-09 2015-03-12 Calixa Therapeutics, Inc. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US20150094293A1 (en) 2013-09-27 2015-04-02 Calixa Therapeutics, Inc. Solid forms of ceftolozane

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268509A (en) * 1978-07-10 1981-05-19 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and processes for preparation thereof
IE49099B1 (en) * 1978-10-27 1985-07-24 Glaxo Group Ltd Cephalosporin compounds
DE2943427A1 (de) * 1978-10-27 1980-05-08 Glaxo Group Ltd Cephalosporinverbindungen
FI793566A (fi) * 1978-11-15 1980-05-16 Glaxo Group Ltd Kefalosporinantibioter
AU536842B2 (en) * 1978-12-29 1984-05-24 Fujisawa Pharmaceutical Co., Ltd. Cephalosporin antibiotics
EP0025017A1 (de) * 1979-08-28 1981-03-11 Ciba-Geigy Ag Polyazathiaverbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate enthaltend solche Verbindungen und Verwendung von letzteren
EP0027599B1 (en) * 1979-10-12 1984-10-03 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds, processes for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
GR78245B (es) 1984-09-26
NZ198336A (en) 1984-05-31
DK405881A (da) 1982-03-13
HU185656B (en) 1985-03-28
ES505409A0 (es) 1983-02-01
ES8401084A1 (es) 1983-12-01
FI812810L (fi) 1982-03-13
EP0047977A3 (de) 1982-10-13
DD201906A5 (de) 1983-08-17
EP0047977A2 (de) 1982-03-24
PT73658A (en) 1981-10-01
ES515426A0 (es) 1983-12-01
PT73658B (en) 1983-10-20
NO813109L (no) 1982-03-15
AU7517181A (en) 1982-03-18
IL63790A0 (en) 1981-12-31

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20001009