ES8302311A1 - Metodo para la determinacion de un analito biologico de interes utilizando agentes pluorescentes encapsulados. - Google Patents

Metodo para la determinacion de un analito biologico de interes utilizando agentes pluorescentes encapsulados.

Info

Publication number
ES8302311A1
ES8302311A1 ES506017A ES506017A ES8302311A1 ES 8302311 A1 ES8302311 A1 ES 8302311A1 ES 506017 A ES506017 A ES 506017A ES 506017 A ES506017 A ES 506017A ES 8302311 A1 ES8302311 A1 ES 8302311A1
Authority
ES
Spain
Prior art keywords
immunoassay
binding partner
test kit
analyte
microencapsulated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES506017A
Other languages
English (en)
Other versions
ES506017A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alfa Wassermann Inc
Electro Nucleonics Inc
Original Assignee
Alfa Wassermann Inc
Electro Nucleonics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Wassermann Inc, Electro Nucleonics Inc filed Critical Alfa Wassermann Inc
Publication of ES8302311A1 publication Critical patent/ES8302311A1/es
Publication of ES506017A0 publication Critical patent/ES506017A0/es
Granted legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/586Liposomes, microcapsules or cells
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/80Fluorescent dyes, e.g. rhodamine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/805Optical property
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/807Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808Automated or kit
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/826Additives, e.g. buffers, diluents, preservatives

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

METODO PARA LA DETERMINACION DE UN ANALITO BIOLOGICO MEDIANTE AGENTES FLUORESCENTES ENCAPSULADOS. CONSISTE EN MARCAR UNA ESPECIE INMUNOLOGICA, ESPECIFICA PARA EL ANALITO, CON UN MATERIAL FLUORESCENTE ENCAPSULADO, BIOLOGICAMENTE COMPATIBLE CON DICHA ESPECIE; PONER EN CONTACTO LA ESPECIE MARCADA CON FLOURESCENTE ENCAPSULADO Y EL MATERIAL BIOLOGICO A ANALIZAR; SEPARAR EL COMPLEJO FORMADO; ROMPER LA CAPSULA QUE CONTIENE EL MARCADOR FLUORESCENTE; PONER EN CONTACTO EL FLUORESCENTE LIBERADO CON UNA FUENTE DE ENERGIA, QUE NO SEA RADIACION ELECTROMAGNETICA, Y CAPAZ DE ACTIVAR EL MARCADOR FLUORESCENTE; Y DETERMINAR LA QUIMILUMINISCENCIA EMITIDA. EL METODO TIENE APLICACIONES EN ANALISIS CLINICOS, CUALI Y CUANTITATIVOS.
ES506017A 1981-02-10 1981-10-05 Metodo para la determinacion de un analito biologico de interes utilizando agentes pluorescentes encapsulados. Granted ES506017A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/233,057 US4372745A (en) 1979-12-19 1981-02-10 Chemical luminescence amplification substrate system for immunochemistry involving microencapsulated fluorescer

Publications (2)

Publication Number Publication Date
ES8302311A1 true ES8302311A1 (es) 1983-01-01
ES506017A0 ES506017A0 (es) 1983-01-01

Family

ID=22875705

Family Applications (2)

Application Number Title Priority Date Filing Date
ES506017A Granted ES506017A0 (es) 1981-02-10 1981-10-05 Metodo para la determinacion de un analito biologico de interes utilizando agentes pluorescentes encapsulados.
ES515013A Expired ES8306260A1 (es) 1981-02-10 1982-08-16 "dispositivo para la determinacion de un analito biologico de interes utilizando agentes fluorescentes encapsulados".

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES515013A Expired ES8306260A1 (es) 1981-02-10 1982-08-16 "dispositivo para la determinacion de un analito biologico de interes utilizando agentes fluorescentes encapsulados".

Country Status (9)

Country Link
US (1) US4372745A (es)
EP (1) EP0070832A4 (es)
BE (1) BE892094R (es)
BR (1) BR8108972A (es)
CA (1) CA1190147A (es)
ES (2) ES506017A0 (es)
IT (1) IT1157258B (es)
WO (1) WO1982002772A1 (es)
ZA (1) ZA82338B (es)

Families Citing this family (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1510183A (en) * 1982-03-26 1983-10-24 Liposome Company, Inc., The Lupus assay method and compositions
EP0090735A3 (en) * 1982-03-26 1986-05-14 The Liposome Corporation Lupus assay method and compositions
US4483929A (en) * 1982-05-03 1984-11-20 Liposome Technology Incorporated Liposomes with glycolipid-linked antibodies
US4480041A (en) * 1982-07-09 1984-10-30 Collaborative Research, Inc. Use of phosphotriester intermediates for preparation of functionalized liposomes
US4517303A (en) * 1982-10-20 1985-05-14 E. I. Du Pont De Nemours And Company Specific binding assays utilizing analyte-cytolysin conjugates
US4668638A (en) * 1983-03-24 1987-05-26 The Liposome Company, Inc. Liposome composition for lupus assay
JPH06105256B2 (ja) * 1983-06-14 1994-12-21 株式会社東芝 免疫分析方法
US4713324A (en) * 1983-09-01 1987-12-15 Technicon Instruments Corporation Inverted latency specific binding assay
GB8401368D0 (en) * 1984-01-19 1984-02-22 Amersham Int Plc Assay method
US4695554A (en) * 1984-02-14 1987-09-22 Becton Dickinson And Company Sac or liposome containing dye (sulforhodamine) for immunoassay
US4957735A (en) * 1984-06-12 1990-09-18 The University Of Tennessee Research Corporation Target-sensitive immunoliposomes- preparation and characterization
US4708933A (en) * 1984-06-12 1987-11-24 Leaf Huang Immunoliposome assay-methods and products
US5082768A (en) * 1984-06-15 1992-01-21 Mast Immunosystems, Inc. Attenuator to suppress extraneous light in luminescent specific-binding assays
US4814270A (en) * 1984-09-13 1989-03-21 Becton Dickinson And Company Production of loaded vesicles
DK365785A (da) * 1984-09-17 1986-03-18 Hoffmann La Roche Metalcomplexer
US5075447A (en) * 1984-09-17 1991-12-24 Hoffmann-La Roche Inc. Ruthenium complexes useful as carriers for immunologically active materials
US5310687A (en) * 1984-10-31 1994-05-10 Igen, Inc. Luminescent metal chelate labels and means for detection
US4743561A (en) * 1985-03-05 1988-05-10 Abbott Laboratories Luminescent assay with a reagent to alter transmitive properties of assay solution
US4678608A (en) * 1985-04-15 1987-07-07 American Cyanamid Company Chemiluminescent composition
JPS61277062A (ja) * 1985-05-31 1986-12-08 Hitachi Ltd 免疫分析方法およびそれに用いる試薬
US4752572A (en) * 1985-08-30 1988-06-21 Eastman Kodak Company Lipid vesicles containing labeled species and their analytical uses
US5017475A (en) * 1985-11-25 1991-05-21 Microbiological Associates, Inc. Fluorescent detection method based on enzyme activated conversion of a fluorophore precursor substrate
DE3545398A1 (de) * 1985-12-20 1987-06-25 Boehringer Mannheim Gmbh Verfahren zur steigerung der quanten-ausbeute bei der oxidation von luminol durch peroxide in gegenwart von peroxidase
US4717511A (en) * 1985-12-26 1988-01-05 American Cyanamid Company Chemiluminescent composition
US5585279A (en) * 1986-01-23 1996-12-17 Davidson; Robert S. Time-resolved luminescence binding assays using a fluorescent transition metal label other than ruthenium
US4698183A (en) * 1986-02-04 1987-10-06 American Cyanamid Company High light output-short duration chemiluminescent compositions
US6451225B1 (en) 1986-04-30 2002-09-17 Igen International, Inc. Electrochemiluminescent reaction utilizing amine-derived reductant
US6165729A (en) * 1986-04-30 2000-12-26 Hyperion Catalysis International, Inc. Electrochemiluminescent reaction utilizing amine-derived reductant
US6271041B1 (en) 1986-04-30 2001-08-07 Igen International, Inc. Electrochemiluminescent reaction utilizing amine-derived reductant
US5707559A (en) * 1986-07-17 1998-01-13 Tropix, Inc. Chemiluminescent 1,2-dioxetane compounds
JP2506396B2 (ja) 1986-07-24 1996-06-12 トロピックス・インコーポレーテッド ジオキセタン類の酵素的に誘導される分解を使用する物質検出法
EP0261719A3 (en) * 1986-09-23 1990-10-10 Akzo N.V. Thermochemiluminescent cyclodextrin complexes
US4891324A (en) * 1987-01-07 1990-01-02 Syntex (U.S.A.) Inc. Particle with luminescer for assays
US4978625A (en) * 1987-10-19 1990-12-18 Becton, Dickinson And Company Fluorescence immunoassay using water insoluble dyes
ATE142622T1 (de) 1987-11-04 1996-09-15 Igen Inc Elektrochemilumineszente rhenium-fraktionen und verfahren
US4950613A (en) * 1988-02-26 1990-08-21 Gen-Probe Incorporated Proteted chemiluminescent labels
US6702986B1 (en) 1988-04-29 2004-03-09 Igen International, Inc. Electrochemiluminescent reaction utilizing amine-derived reductant
US5256532A (en) * 1988-05-02 1993-10-26 Zynaxis Technologies, Inc. Methods, reagents and test kits for determination of subpopulations of biological entities
US5389523A (en) * 1988-05-31 1995-02-14 The United States Of Americas, As Represented By The Secretary Of Commerce Liposome immunoanalysis by flow injection assay
JP2656564B2 (ja) * 1988-08-26 1997-09-24 株式会社日立製作所 免疫分析方法
US5238610A (en) * 1988-10-06 1993-08-24 The United States Of America As Represented By The Secretary Of The Navy Method of detecting oxidizing agents in aqueous media through the use of chemiluminescent microemulsions
CA2002083C (en) * 1988-11-03 2001-01-09 Haresh P. Shah Enhanced electrochemiluminescence
MY104234A (en) * 1988-11-17 1994-02-28 Becton Dickinson Co Immunoassay on a preblocked solid surface
AU6602890A (en) * 1989-10-05 1991-04-28 Exoxemis, Inc. Haloperoxidase acid optimum chemiluminescence assay system
WO1991005605A1 (en) * 1989-10-10 1991-05-02 Kosak Kenneth M Cyclodextrin labels for immunoassay and biochemical analysis
US5108899A (en) * 1989-10-31 1992-04-28 Exoxemis, Inc. Chemiluminescence assay of in vivo inflammation
US5375606A (en) * 1990-02-28 1994-12-27 Zynaxis, Inc. Bio-analytical separation method
US5121302A (en) * 1990-12-24 1992-06-09 American Cyanamid Company Solid, thin chemiluminescent device
DK0608370T3 (da) * 1991-10-15 1998-09-07 Multilyte Ltd Bindingsassay med anvendelse af mærket reagens
US6399397B1 (en) 1992-09-14 2002-06-04 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
US5736410A (en) 1992-09-14 1998-04-07 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
US6159686A (en) 1992-09-14 2000-12-12 Sri International Up-converting reporters for biological and other assays
US5437274A (en) * 1993-02-25 1995-08-01 Gholam A. Peyman Method of visualizing submicron-size vesicles and particles in blood circulation
AU687363B2 (en) * 1993-03-19 1998-02-26 Ciba Corning Diagnostics Corp. Luminometer
GB9310468D0 (en) * 1993-05-20 1993-07-07 Oxford Glycosystems Ltd Sugar complexes
US6316180B1 (en) 1995-01-04 2001-11-13 Igen International, Inc. Electrochemiluminescent monitoring of compounds/electrochemiluminescence assays
US5643713A (en) * 1995-06-07 1997-07-01 Liang; Pam Electrochemiluminescent monitoring of compounds
US20010003647A1 (en) * 1995-06-07 2001-06-14 Ji Sun Coreatant-including electrochemiluminescent compounds, methods, systems and kits utilizing same
AU5665196A (en) * 1995-04-18 1996-11-07 Igen, Inc. Electrochemiluminescence of rare earth metal chelates
EA199700257A1 (ru) * 1995-04-25 1998-12-24 Ирори Матрицы с памятью, программируемые на расстоянии, и их использование
US5679519A (en) * 1995-05-09 1997-10-21 Oprandy; John J. Multi-label complex for enhanced sensitivity in electrochemiluminescence assay
US6319670B1 (en) * 1995-05-09 2001-11-20 Meso Scale Technology Llp Methods and apparatus for improved luminescence assays using microparticles
US5686046A (en) * 1995-07-13 1997-11-11 Chiron Diagnostics Corporation Luminometer
US5856194A (en) 1996-09-19 1999-01-05 Abbott Laboratories Method for determination of item of interest in a sample
US5795784A (en) 1996-09-19 1998-08-18 Abbott Laboratories Method of performing a process for determining an item of interest in a sample
US5800999A (en) 1996-12-16 1998-09-01 Tropix, Inc. Dioxetane-precursor-labeled probes and detection assays employing the same
US7745142B2 (en) * 1997-09-15 2010-06-29 Molecular Devices Corporation Molecular modification assays
US7632651B2 (en) * 1997-09-15 2009-12-15 Mds Analytical Technologies (Us) Inc. Molecular modification assays
US20050227294A1 (en) * 1997-09-15 2005-10-13 Molecular Devices Corporation Molecular modification assays involving lipids
US7070921B2 (en) 2000-04-28 2006-07-04 Molecular Devices Corporation Molecular modification assays
EP1025217B1 (en) * 1997-10-24 2006-10-04 Invitrogen Corporation Recombinational cloning using nucleic acids having recombination sites
CA2283597C (en) 1998-10-02 2008-02-05 Ortho-Clinical Diagnostics, Inc. Reduced cortisol conjugates
US6410255B1 (en) * 1999-05-05 2002-06-25 Aurora Biosciences Corporation Optical probes and assays
US7198924B2 (en) 2000-12-11 2007-04-03 Invitrogen Corporation Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
US20020155507A1 (en) 2000-10-06 2002-10-24 Bruchez Marcel P. Cells having a spectral signature, and methods of preparation and use thereof
US6939721B2 (en) * 2000-12-18 2005-09-06 Agilent Technologies, Inc. Fluorescence immunoassays using organo-metallic complexes for energy transfer
US6461543B2 (en) * 2001-01-17 2002-10-08 Omniglow Corporation Chemiluminescent solution based on disubstituted perylene tetracarboxylic acids, their dianhydrides and diimides
US7727752B2 (en) * 2003-07-29 2010-06-01 Life Technologies Corporation Kinase and phosphatase assays
US7619059B2 (en) * 2003-07-29 2009-11-17 Life Technologies Corporation Bimolecular optical probes
CA2445420A1 (en) * 2003-07-29 2005-01-29 Invitrogen Corporation Kinase and phosphatase assays
US20050069929A1 (en) 2003-08-08 2005-03-31 Invitrogen Corporation Methods and compositions for seamless cloning of nucleic acid molecules
US20060035242A1 (en) 2004-08-13 2006-02-16 Michelitsch Melissa D Prion-specific peptide reagents
EP1671128B1 (en) * 2003-09-12 2010-02-17 Life Technologies Corporation Applications of the resonance energy transfer between terbium and GFP
US20090298048A1 (en) * 2003-11-03 2009-12-03 Integrigen, Inc. Non-fluorescent, non-enzymatic, chemiluminescent aqueous assay
JP2007512838A (ja) 2003-12-01 2007-05-24 インヴィトロジェン コーポレーション 組換え部位を含む核酸分子およびその使用方法
WO2005084404A2 (en) * 2004-03-03 2005-09-15 Cornell Research Foundation, Inc. Microfluidic biosensor and methods of use
US8029985B2 (en) * 2004-09-01 2011-10-04 Vybion, Inc. Amplified bioassay
TW200643171A (en) * 2005-06-07 2006-12-16 Temasek Life Sciences Lab Ltd Porcine circovirus type 2 vaccines
EP3211011A1 (en) 2007-11-16 2017-08-30 Nuvelo, Inc. Antibodies to lrp6
US20120107834A1 (en) * 2009-01-16 2012-05-03 Angros Lee H Encapsulated reagents and methods of use
US20140087362A1 (en) 2012-03-16 2014-03-27 Aladar A. Szalay Methods for assessing effectiveness and monitoring oncolytic virus treatment
US9297768B2 (en) * 2013-04-18 2016-03-29 Empire Technology Development Llc Methods and systems for labeling and detecting defects in a graphene layer
US20180258473A1 (en) * 2015-11-10 2018-09-13 Administracion General De La Comunidad Autonoma De Euskadi Diagnostic methods and devices
CN115175680A (zh) 2019-10-18 2022-10-11 加利福尼亚大学董事会 Plxdc激活剂及其用于治疗血管病症的用途

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3401123A (en) * 1961-03-15 1968-09-10 Ncr Co Process for making case-hardened capsules and its capsule product
NL152290B (nl) * 1965-09-08 1977-02-15 American Cyanamid Co Werkwijze ter bereiding van chemiluminescerende mengsels.
GB1270999A (en) * 1969-07-30 1972-04-19 Bdh Pharmaceuticals Ltd Propane-1,2-diol derivatives
US3704231A (en) * 1971-02-16 1972-11-28 American Cyanamid Co Chemiluminescent additives
US3817837A (en) * 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3887698A (en) * 1973-03-12 1975-06-03 Univ Leland Stanford Junior Sacs with epitopic sites on walls enclosing stable free radicals
US3935074A (en) * 1973-12-17 1976-01-27 Syva Company Antibody steric hindrance immunoassay with two antibodies
GB1461877A (en) 1974-02-12 1977-01-19 Wellcome Found Assay method utilizing chemiluminescence
US4199559A (en) * 1974-08-12 1980-04-22 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4169137A (en) * 1974-12-20 1979-09-25 Block Engineering, Inc. Antigen detecting reagents
US4011219A (en) * 1975-03-28 1977-03-08 Chugai Seiyaku Kabushiki Kaisha Phthalazine derivatives and salts thereof
US4018884A (en) * 1975-06-26 1977-04-19 Hoffmann-La Roche Inc. Fluorogenic materials and labeling techniques
US4181650A (en) * 1975-08-25 1980-01-01 Maier Charles L Jr Procedure for the assay of pharmacologically immunologically and biochemically active compounds in biological fluids
US4201763A (en) * 1975-10-09 1980-05-06 Bio-Rad Laboratories, Inc. Solid phase immunofluorescent assay method
US4036946A (en) * 1975-10-20 1977-07-19 Marcos Kleinerman Immunofluorometric method for measuring minute quantities of antigens, antibodies and other substances
US4020151A (en) * 1976-02-17 1977-04-26 International Diagnostic Technology, Inc. Method for quantitation of antigens or antibodies on a solid surface
US4160818A (en) * 1976-04-15 1979-07-10 Technicon Instruments Corporation Fluorimetric immunoassay for diphenylhydantoin
US4326008A (en) * 1976-08-27 1982-04-20 California Institute Of Technology Protein specific fluorescent microspheres for labelling a protein
US4235792A (en) * 1977-04-14 1980-11-25 The Governing Council Of The University Of Toronto Immunological materials
GB2008247B (en) * 1977-11-17 1982-12-15 Welsh Nat School Med Detecting or quantifying substances using labelling techniques
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4277437A (en) * 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4193983A (en) * 1978-05-16 1980-03-18 Syva Company Labeled liposome particle compositions and immunoassays therewith
US4255411A (en) * 1978-11-27 1981-03-10 Damon Corporation Process of determining an immunogenic substance by competition with an antibody in a microcapsule
US4241046A (en) * 1978-11-30 1980-12-23 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4342739A (en) * 1979-01-09 1982-08-03 Fuji Photo Film Co., Ltd. Novel material for immunological assay of biochemical components and a process for the determination of said components
US4238195A (en) * 1979-01-18 1980-12-09 Miles Laboratories, Inc. Fluorescer-labeled specific binding assays
US4280816A (en) * 1979-10-25 1981-07-28 Nasik Elahi Macroencapsulated immunosorbent assay technique and element therefor
WO1981001883A1 (en) * 1979-12-19 1981-07-09 Electro Nucleonics Chemical luminescence amplification substrate system for immunochemistry
US4342826A (en) * 1980-02-04 1982-08-03 Collaborative Research, Inc. Immunoassay products and methods

Also Published As

Publication number Publication date
CA1190147A (en) 1985-07-09
ES515013A0 (es) 1983-05-01
US4372745A (en) 1983-02-08
ES506017A0 (es) 1983-01-01
ZA82338B (en) 1982-11-24
BE892094R (fr) 1982-08-10
BR8108972A (pt) 1983-01-11
IT1157258B (it) 1987-02-11
EP0070832A4 (en) 1983-06-17
IT8219574A0 (it) 1982-02-10
EP0070832A1 (en) 1983-02-09
WO1982002772A1 (en) 1982-08-19
ES8306260A1 (es) 1983-05-01

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