ES2052505T3 - Procedimiento y reactivo para la determinacion de un participe reaccionante en una reaccion inmunologica. - Google Patents

Procedimiento y reactivo para la determinacion de un participe reaccionante en una reaccion inmunologica.

Info

Publication number
ES2052505T3
ES2052505T3 ES87104034T ES87104034T ES2052505T3 ES 2052505 T3 ES2052505 T3 ES 2052505T3 ES 87104034 T ES87104034 T ES 87104034T ES 87104034 T ES87104034 T ES 87104034T ES 2052505 T3 ES2052505 T3 ES 2052505T3
Authority
ES
Spain
Prior art keywords
receptor
determination
unmarked
reactioning
participant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87104034T
Other languages
English (en)
Inventor
Klaus Peter Dr Kaspar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Application granted granted Critical
Publication of ES2052505T3 publication Critical patent/ES2052505T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/809—Multifield plates or multicontainer arrays
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/819—Multifunctional antigen or antibody
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/825—Pretreatment for removal of interfering factors from sample
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/826—Additives, e.g. buffers, diluents, preservatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PARA DETERMINACION DE UN AGENTE DE REACCION DE UNA REACCION INMUNOLOGICA SEGUN EL PRINCIPIO DE INMUNOASAYS SE LLEVA EL AGENTE REACTIVO A DETERMINAR CON UN RECEPTOR R1 ESPECIFICO MARCADO Y AL MENOS UN RECEPTOR R2 NO MARCADO EN CONTACTO, CON LO QUE UNO DE LOS RECEPTORES R2 NO MARCADOS SE CONECTA EN UNA FASE DE FIJACION SOBRE UNA SUSTANCIA R3 COMBINABLE. PARA DETERMINACION DE LOS VALORES VACIOS DE PRUEBAS SE EEMPLAZA EL RECEPTOR R2 NO MARCADO QUE SE CONECTA DEL RECEPTOR FIJADO EN LA FASE DE FIJADO, MEDIANTE OTRO RECEPTOR R2 NO MARCADO QUE NO REACCIONA CON EL AGENTE DE REACCION A DETERMINAR DE R2.
ES87104034T 1986-03-19 1987-03-19 Procedimiento y reactivo para la determinacion de un participe reaccionante en una reaccion inmunologica. Expired - Lifetime ES2052505T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863609217 DE3609217A1 (de) 1986-03-19 1986-03-19 Verfahren und reagenz zur bestimmung eines reaktionspartners einer immunologischen reaktion

Publications (1)

Publication Number Publication Date
ES2052505T3 true ES2052505T3 (es) 1994-07-16

Family

ID=6296758

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87104034T Expired - Lifetime ES2052505T3 (es) 1986-03-19 1987-03-19 Procedimiento y reactivo para la determinacion de un participe reaccionante en una reaccion inmunologica.

Country Status (6)

Country Link
US (1) US4880731A (es)
EP (1) EP0243655B1 (es)
JP (1) JPH0670629B2 (es)
AT (1) ATE80466T1 (es)
DE (2) DE3609217A1 (es)
ES (1) ES2052505T3 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3901458A1 (de) * 1989-01-19 1990-07-26 Behringwerke Ag Verwendung von zwei- oder dreiwertigen kationen in immunchemischen tests
DE4024476C1 (es) * 1990-08-02 1992-02-27 Boehringer Mannheim Gmbh, 6800 Mannheim, De
CA2072758A1 (en) * 1990-09-14 1992-03-15 Kenneth Francis Buechler Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays
JP2509840B2 (ja) * 1992-03-03 1996-06-26 三洋化成工業株式会社 免疫測定法及び免疫測定用試薬キット
JP2547149B2 (ja) * 1992-03-05 1996-10-23 三洋化成工業株式会社 免疫測定法及び免疫測定用試薬キット
US5399500A (en) * 1992-06-26 1995-03-21 Becton Dickinson And Company Two step process for coating of antibodies to a solid phase
US5792617A (en) * 1994-08-18 1998-08-11 Rotman; M. Boris Cell proliferation-based amplified detection of analytes
US6610494B2 (en) * 1996-05-14 2003-08-26 Ronald R. Marquardt Solid-phase activity assay for biologically active substance
DE19808226C1 (de) * 1998-02-27 2000-03-02 Bruker Analytik Gmbh Anordnung und Verfahren zur Untersuchung von hydrophilen Makromolekülen in wässriger Lösung
US6162400A (en) * 1998-08-12 2000-12-19 Agilent Technologies, Inc. Apparatus for controlling reactions
US20040018577A1 (en) 2002-07-29 2004-01-29 Emerson Campbell John Lewis Multiple hybrid immunoassay
JP2008058194A (ja) * 2006-08-31 2008-03-13 Kobe Univ ウエストナイルウイルス感染の鑑別方法
US8404441B2 (en) 2010-04-19 2013-03-26 Empire Technology Development Llc DNA intercalator detection
JP7477522B2 (ja) * 2019-10-25 2024-05-01 メタウォーター株式会社 濃度測定方法、濃度測定装置およびプログラム

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4294817A (en) * 1977-11-25 1981-10-13 International Diagnostic Technology, Inc. Method of fluoro immunoassay
US4320109A (en) * 1979-06-29 1982-03-16 The University Of Southern California Immunoradiometric assay employing terminal radionuclide labeling and synthesis of conjugates for such assay
FR2486657A1 (fr) * 1980-07-09 1982-01-15 Pasteur Institut Procede de detection et de dosage d'une substance biologique par erythroadsorption
DE3263249D1 (en) * 1981-08-21 1985-05-30 Hoffmann La Roche Method for the determination of carcinoembryonic antigen (cea) and suitable antibody solution for the determination
IL68506A (en) * 1982-05-04 1988-06-30 Syva Co Simultaneous calibration heterogeneous immunoassay method and device and kit for use therein
DE3225027A1 (de) * 1982-07-05 1984-01-05 Boehringer Mannheim Gmbh, 6800 Mannheim Immunchemisches messverfahren
US4535057A (en) * 1982-07-26 1985-08-13 Amf Incorporated Immunoassay employing monoclonal herpes simplex antibody and biotin-avidin detection system
US4558013A (en) * 1983-04-08 1985-12-10 Mast Immunosystems, Ltd. Calibrated reaction measurement system
US4791056A (en) * 1984-03-27 1988-12-13 Syntex (U.S.A.) Inc. Calibration device for heterogeneous immunoassay
EP0227748A1 (en) * 1985-06-17 1987-07-08 Electro-Nucleonics, Inc. Test for determining false positive reactions in a testing procedure to detect the presence of antibody to microorganisms.

Also Published As

Publication number Publication date
DE3781582D1 (de) 1992-10-15
JPH0670629B2 (ja) 1994-09-07
US4880731A (en) 1989-11-14
ATE80466T1 (de) 1992-09-15
JPS63118655A (ja) 1988-05-23
EP0243655A2 (de) 1987-11-04
EP0243655B1 (de) 1992-09-09
EP0243655A3 (de) 1991-01-16
DE3609217A1 (de) 1987-09-24

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