ES8201549A1 - Procedimiento para la obtencion de derivados de 3,4,5-trihi-droxipiperidina - Google Patents

Procedimiento para la obtencion de derivados de 3,4,5-trihi-droxipiperidina

Info

Publication number
ES8201549A1
ES8201549A1 ES499782A ES499782A ES8201549A1 ES 8201549 A1 ES8201549 A1 ES 8201549A1 ES 499782 A ES499782 A ES 499782A ES 499782 A ES499782 A ES 499782A ES 8201549 A1 ES8201549 A1 ES 8201549A1
Authority
ES
Spain
Prior art keywords
preparation
medicines
animal feeding
trihydroxypiperidine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES499782A
Other languages
English (en)
Other versions
ES499782A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES499782A0 publication Critical patent/ES499782A0/es
Publication of ES8201549A1 publication Critical patent/ES8201549A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A23K20/132—Heterocyclic compounds containing only one nitrogen as hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE 3,4,5-TRIHIDROXIPIPERDINA DE FORMULA (I), EN LA QUE X ES UN RADICAL HIROCARBONADO; Y ES OXIGENO O AZUFRE; Y R1, R2 Y R3 PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE ALQUILACION DE UN COMPUESTO DE FORMULA (II) CON UN AGENTE DE ALQUILACION DE FORMULA (III), SIGUIENDO METODOS CONVENCIONALES; FORMULAS EN LAS QUE X, Y, R1, R2 Y R3 TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I) Y Z ES UN GRUPO FUNCIONAL USUAL EN UN AGENTE DE ALGUILACION, TAL COMO UN HALURO O UN ESTER DE UN ACIDO SULFONICO. TAMBIEN SE PUEDEN OBTENER LOS COMPUESTOS DE FORMULA (I) POR TRATAMIENTO DE UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (IV) SIGUIENDO UN PROCEDIMIENTO DE ALQUILACION REDUCIDA, EN AL QUE A TIENE EL MISMO SIGNIFICADO QUE X CON UN ATOMO DE CARBONO MENOS.
ES499782A 1980-02-26 1981-02-25 Procedimiento para la obtencion de derivados de 3,4,5-trihi-droxipiperidina Expired ES8201549A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803007078 DE3007078A1 (de) 1980-02-26 1980-02-26 Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel sowie in der tierernaehrung

Publications (2)

Publication Number Publication Date
ES499782A0 ES499782A0 (es) 1981-12-16
ES8201549A1 true ES8201549A1 (es) 1981-12-16

Family

ID=6095540

Family Applications (1)

Application Number Title Priority Date Filing Date
ES499782A Expired ES8201549A1 (es) 1980-02-26 1981-02-25 Procedimiento para la obtencion de derivados de 3,4,5-trihi-droxipiperidina

Country Status (18)

Country Link
US (1) US4407809A (es)
EP (1) EP0034784B1 (es)
JP (3) JPS56133267A (es)
AT (1) ATE8623T1 (es)
AU (1) AU538463B2 (es)
CA (1) CA1160634A (es)
DE (2) DE3007078A1 (es)
DK (1) DK153545C (es)
ES (1) ES8201549A1 (es)
FI (1) FI75807C (es)
GR (1) GR73691B (es)
HU (1) HU183346B (es)
IE (1) IE51317B1 (es)
IL (1) IL62198A (es)
NO (1) NO155804B (es)
PT (1) PT72507B (es)
SU (1) SU1014471A3 (es)
ZA (1) ZA811252B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3737523A1 (de) * 1987-11-05 1989-05-18 Bayer Ag Verwendung von substituierten hydroxypiperidinen als antivirale mittel
US5192772A (en) * 1987-12-09 1993-03-09 Nippon Shinyaku Co. Ltd. Therapeutic agents
GB8827701D0 (en) * 1987-12-09 1988-12-29 Nippon Shinyaku Co Ltd Thrombolytic &c compositions
US4985445A (en) * 1988-02-12 1991-01-15 Meiji Seika Kaisha, Ltd. Cancer cell metastasis inhibitors and novel compounds
EP0491041A4 (en) * 1989-09-07 1993-03-03 Nippon Shinyaku Company, Limited Antiviral drug
US5252587A (en) * 1990-04-27 1993-10-12 Merrell Dow Pharmaceuticals, Inc. N-derivatives of 1-deoxy nojirimycin
US5536732A (en) * 1990-04-27 1996-07-16 Merrell Pharmaceuticals Inc. N-derivatives of 1-deoxy nojirimycin
US5258518A (en) * 1992-04-01 1993-11-02 G. D. Searle & Co. 2-substituted tertiary carbinol derivatives of deoxynojirimycin
AU732552B2 (en) * 1996-07-15 2001-04-26 Genzyme Corporation Deoxynojirimycin derivatives and their uses as glucosylceramidase inhibitors
GB0100889D0 (en) 2001-01-12 2001-02-21 Oxford Glycosciences Uk Ltd Compounds
AU2003248960B2 (en) 2002-07-17 2009-06-25 Idorsia Pharmaceuticals Ltd Piperidinetriol derivatives as inhibitors of glycosylceramidsynthase
JP4575156B2 (ja) * 2002-07-17 2010-11-04 アクテリオン ファーマシューティカルズ リミテッド グルコシルセラミドシンターゼの阻害剤としてのピペリジントリオール誘導体
GB0313678D0 (en) * 2003-06-13 2003-07-16 Oxford Glycosciences Uk Ltd Novel compounds
GB0313677D0 (en) * 2003-06-13 2003-07-16 Oxford Glycosciences Uk Ltd Novel compound
US8975280B2 (en) * 2006-05-24 2015-03-10 The Chancellor, Masters And Scholars Of The University Of Oxford Deoxynojirimycin and D-arabinitol analogs and methods of using
WO2010027996A1 (en) * 2008-09-02 2010-03-11 Institute For Hepatitis And Virus Research Novel imino sugar derivatives demonstrate potent antiviral activity and reduced toxicity
CA2875975A1 (en) * 2012-06-06 2013-12-12 Unither Virology, Llc Novel iminosugars and their applications
EP3046558B1 (en) * 2013-09-16 2019-08-14 Emergent Virology LLC Deoxynojirimycin derivatives and methods of their using

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1555654A (en) * 1977-06-25 1979-11-14 Exxon Research Engineering Co Agricultural burner apparatus
NO154918C (no) * 1977-08-27 1987-01-14 Bayer Ag Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.
GB2020278B (en) * 1978-05-03 1983-02-23 Nippon Shinyaku Co Ltd Moranoline dervitives
DE2839309A1 (de) * 1978-09-09 1980-03-27 Bayer Ag 3,4,5-trihydroxypiperidin-derivate
JPS5683409A (en) * 1979-12-13 1981-07-08 Nippon Shinyaku Co Ltd Plant growth regulator
DE3322006A1 (de) * 1983-06-18 1984-12-20 Robert Bosch Gmbh, 7000 Stuttgart Vorrichtung zur steuerung eines induktiven stellgliedes, insbesondere eines vergasers

Also Published As

Publication number Publication date
JPS60166663A (ja) 1985-08-29
NO810485L (no) 1981-08-27
PT72507A (en) 1981-03-01
GR73691B (es) 1984-04-03
JPS60166616A (ja) 1985-08-29
JPS6152147B2 (es) 1986-11-12
SU1014471A3 (ru) 1983-04-23
IE810391L (en) 1981-08-26
DK153545B (da) 1988-07-25
ES499782A0 (es) 1981-12-16
FI75807B (fi) 1988-04-29
DE3007078A1 (de) 1981-09-10
AU6748081A (en) 1981-09-03
CA1160634A (en) 1984-01-17
DK153545C (da) 1988-12-05
HU183346B (en) 1984-04-28
FI810559L (fi) 1981-08-27
IL62198A (en) 1985-03-31
IL62198A0 (en) 1981-03-31
FI75807C (fi) 1988-08-08
DE3164944D1 (en) 1984-08-30
US4407809A (en) 1983-10-04
JPS56133267A (en) 1981-10-19
PT72507B (en) 1982-02-05
ATE8623T1 (de) 1984-08-15
IE51317B1 (en) 1986-12-10
EP0034784A1 (de) 1981-09-02
DK84181A (da) 1981-08-27
ZA811252B (en) 1982-03-31
EP0034784B1 (de) 1984-07-25
JPH0342243B2 (es) 1991-06-26
AU538463B2 (en) 1984-08-16
NO155804B (no) 1987-02-23

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