ES8200896A1 - Procedimiento para la obtencion de compuestos de acido aci- lamino-3-cefem-4-carboxilico - Google Patents

Procedimiento para la obtencion de compuestos de acido aci- lamino-3-cefem-4-carboxilico

Info

Publication number
ES8200896A1
ES8200896A1 ES497849A ES497849A ES8200896A1 ES 8200896 A1 ES8200896 A1 ES 8200896A1 ES 497849 A ES497849 A ES 497849A ES 497849 A ES497849 A ES 497849A ES 8200896 A1 ES8200896 A1 ES 8200896A1
Authority
ES
Spain
Prior art keywords
group
index
compounds
formula
nhso2
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES497849A
Other languages
English (en)
Other versions
ES497849A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES497849A0 publication Critical patent/ES497849A0/es
Publication of ES8200896A1 publication Critical patent/ES8200896A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C07D233/38—One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28—Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTO DE ACIDO ACILAMINO-3-CEFEM-4-CARBOXILICO, DE FORMULA (I), DONDE N ES UN NUMERO ENTERO DE 1 A 4; M ES 0 O 1; X SIGNIFICA OZIGENO, AZUFRE O EL GRUPO -NH-;W SIGNIFICA UN GRUPO -CO-, -CO-NHSO2- O -SO2NH-CO-; A SIGNIFICA FENILO, TIENILO O FURILENO; Z SIGNIFICA OXIGENO O AZUFRE; YSIGNIFICA ALQUILENO INFERIOR; K ES 1 O 2; R4 SIGNIFICA HIDROGENO, UN RESTO ALIFATICO INFERIOR O CICLOALIFATICO; R1 SIGNIFICA HIDROGENO, ALQUILO INFERIOR, ALCOXI INFERIOR, HALOGENO O UN GRUPO - CH2-R2, DONDE R2 SIGNIFICA UN GRUPO HIDROXI O MERCAPTO; R3 SIGNIFICA HIDROGENO O METOXI, Y LAS SALES DE ADICION, FARMACEUTICAMENTE ACEPTABLES.
ES497849A 1979-12-19 1980-12-17 Procedimiento para la obtencion de compuestos de acido aci- lamino-3-cefem-4-carboxilico Expired ES8200896A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1128379 1979-12-19

Publications (2)

Publication Number Publication Date
ES497849A0 ES497849A0 (es) 1981-11-16
ES8200896A1 true ES8200896A1 (es) 1981-11-16

Family

ID=4371942

Family Applications (1)

Application Number Title Priority Date Filing Date
ES497849A Expired ES8200896A1 (es) 1979-12-19 1980-12-17 Procedimiento para la obtencion de compuestos de acido aci- lamino-3-cefem-4-carboxilico

Country Status (9)

Country Link
US (1) US4464366A (es)
EP (1) EP0031794A3 (es)
JP (1) JPS56103186A (es)
AU (1) AU6551880A (es)
DK (1) DK540880A (es)
ES (1) ES8200896A1 (es)
IL (1) IL61751A0 (es)
NZ (1) NZ195875A (es)
ZA (1) ZA807914B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0059683A3 (de) * 1981-02-27 1982-12-01 Ciba-Geigy Ag 7-Acylamido-3-cephem-4-carbonsäureverbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate, welche diese Verbindungen enthalten, und Verwendung von letzteren
GT200500282A (es) * 2004-10-12 2006-05-04 Heteroatomos conteniendo compuestos triciclicos.
US20110118462A1 (en) * 2009-11-18 2011-05-19 Guangzhou Baiyunshan Pharmaceutical Co., Ltd. Guangzhou Baiyunshan Pharmaceutical Factory N-heterocyclic substituent-containing antibiotic, preparation and use thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4338438A (en) * 1970-06-16 1982-07-06 Merck & Co., Inc. Cephalosporin antibiotics
DE2407715C2 (de) * 1974-02-18 1982-12-02 Bayer Ag, 5090 Leverkusen Cephalosporine, Verfahren zu ihrer Herstellung sowie Arzneimittel
US4112090A (en) * 1974-05-09 1978-09-05 Toyama Chemical Co., Ltd. Novel penicillins and cephalosporins and process for producing the same
US4087424A (en) * 1974-05-09 1978-05-02 Toyama Chemical Co., Ltd. Novel penicillins and cephalosporins and process for producing the same
US4219554A (en) * 1974-05-09 1980-08-26 Toyama Chemical Company, Limited Novel penicillins and cephalosporins and process for producing same
DE2720579A1 (de) * 1977-05-07 1978-11-09 Bayer Ag Beta-lactam-verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
EP0016900B1 (de) * 1977-07-18 1983-11-16 Ciba-Geigy Ag Zwischenprodukte für die Herstellung von Cephalosporinderivaten, Verfahren zu ihrer Herstellung und Verwendung
US4313945A (en) * 1978-11-23 1982-02-02 Ciba-Geigy Corporation 7-Thiazolyl-acetamido-cephem derivatives with terminal aminocarboxylic acid grouping
EP0015240A1 (de) * 1979-02-16 1980-09-03 Ciba-Geigy Ag Azacyclyl (thio) ureidoacetyl-Verbindungen und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
US4464366A (en) 1984-08-07
ES497849A0 (es) 1981-11-16
ZA807914B (en) 1982-01-27
EP0031794A2 (de) 1981-07-08
EP0031794A3 (de) 1982-02-03
IL61751A0 (en) 1981-01-30
DK540880A (da) 1981-06-20
JPS56103186A (en) 1981-08-18
NZ195875A (en) 1983-04-12
AU6551880A (en) 1981-06-25

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