ES8200373A1 - Procedure for the preparation of polyenmacrolide antibiotic derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of polyenmacrolide antibiotic derivatives. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES8200373A1
ES8200373A1 ES492082A ES492082A ES8200373A1 ES 8200373 A1 ES8200373 A1 ES 8200373A1 ES 492082 A ES492082 A ES 492082A ES 492082 A ES492082 A ES 492082A ES 8200373 A1 ES8200373 A1 ES 8200373A1
Authority
ES
Spain
Prior art keywords
polyenmacrolide
antibiotic
translation
preparation
machine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES492082A
Other languages
Spanish (es)
Other versions
ES492082A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ZA00795508A external-priority patent/ZA795508B/en
Application filed by Schering Corp filed Critical Schering Corp
Publication of ES8200373A1 publication Critical patent/ES8200373A1/en
Publication of ES492082A0 publication Critical patent/ES492082A0/en
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

PREPARATION OF ANTIBIOTIC DERIVATIVES OF POLYENMACROLODA OF GENERAL FORMULA (I) AND ITS ADDITIONAL SALTS OF PHARMACEUTICALLY ACCEPTABLE ACID. CONSISTING IN OBTAINING THE COMPOUNDS (I) BY REACTION OF A N-IODOACETILE DERIVATIVE OF THE ANTIBIOTIC OF POLYENMACROLIDE WITH AN AMINE OF GENERAL FORMULA H2NR1, IN WHICH FORMULAS M IS A PORTION OF ANTIBIOTIC OF POLYENMACROLIDE CONTAINING A PORTAIN AMOUTY IT IS REPLACED BY X, WHERE X IS -CO-CH2-NHR1, WHICH IS R1 HYDROGEN OR A STRAIGHT CHAIN RENT GROUP WITH 1 TO 3 CARBON ATOMS, WHICH MAY BE REPLACED BY A NH2 GROUP; "Z" IS 0 O 1; AND IT IS HYDROGEN, AN ALKYL GROUP OF 1 TO 10 ATOMS OF CARBON, ALYL, PROPARGYL, BENCIL OR PHENYL PORPARGYL. THE N-IDOACETILL DERIVATIVES OF POLYENMACROLIDE ANTIBIOTICS CAN BE PREPARED BY REACTING THE MAIN MACROLIDE WITH IDOACETIC ANHYDRIDE IN A POLAR SOLVENT. THE COMPOUNDS OBTAINED ARE ESPECIALLY USEFUL AS ANTIFUNGICIDE AGENTS. (Machine-translation by Google Translate, not legally binding)
ES492082A 1978-10-23 1980-06-02 PROCEDURE FOR THE PREPARATION OF ANTIBIOTI-CO DERIVATIVES OF POLYENMACROLIDE Granted ES492082A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95382478A 1978-10-23 1978-10-23
ZA00795508A ZA795508B (en) 1978-10-23 1979-10-16 Derivatives of polyene macrolide antibiotics containing an amino sugar moiety, process for the preparation thereof, and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
ES8200373A1 true ES8200373A1 (en) 1981-10-16
ES492082A0 ES492082A0 (en) 1981-10-16

Family

ID=27130340

Family Applications (2)

Application Number Title Priority Date Filing Date
ES485140A Granted ES485140A0 (en) 1978-10-23 1979-10-18 PROCEDURE FOR THE PREPARATION OF ANTIBIOTI-CO DERIVATIVES OF POLYENMACROLIDE
ES492082A Granted ES492082A0 (en) 1978-10-23 1980-06-02 PROCEDURE FOR THE PREPARATION OF ANTIBIOTI-CO DERIVATIVES OF POLYENMACROLIDE

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES485140A Granted ES485140A0 (en) 1978-10-23 1979-10-18 PROCEDURE FOR THE PREPARATION OF ANTIBIOTI-CO DERIVATIVES OF POLYENMACROLIDE

Country Status (1)

Country Link
ES (2) ES485140A0 (en)

Also Published As

Publication number Publication date
ES8102146A1 (en) 1980-12-16
ES485140A0 (en) 1980-12-16
ES492082A0 (en) 1981-10-16

Similar Documents

Publication Publication Date Title
FI882081A (en) 2-SUBSTITUTE E-FUSIONERADE (1,2,4) TRIAZOLO (1,5-C) PYRIMIDINER, PHARMACEUTICAL COMPOSITION OF THE SUBSTANCE OF THE PRODUCT.
ES446571A1 (en) Vinca alkaloid derivatives
IE41528L (en) Furfuryl-benzomorphane derivatives.
ES394370A1 (en) Pharmacologically active 3-piperazinyl-carbonyloxy-2-pyridyl-isoindolin-1-ones
KR840001555A (en) Method for preparing substituted 2-phenyl-2- (pyridylbath) -ethylamine and its back distributor compounds and their acid addition salts
ES484718A1 (en) Chromanol derivatives, a process for their preparation and pharmaceutical compositions comprising them.
SE7601206L (en) ACETYLENE DERIVATIVES
ES458719A1 (en) Substituted 4-phenylurazoles and their use in agricultural fungicide compositions
ES418827A1 (en) 2-aminoindane derivatives
ES8200373A1 (en) Procedure for the preparation of polyenmacrolide antibiotic derivatives. (Machine-translation by Google Translate, not legally binding)
ES435274A1 (en) Substituted benzamides
ES437790A1 (en) Therapeutic compositions containing methylamine derivatives or their salts
ES475596A1 (en) Phenoxyalkanolamine derivatives
ATE78032T1 (en) 2-PYRIDYLACETIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
ES419142A1 (en) 2-2-2-methyl-5-nitro-1-imidazolyl-ethyl-2-thiopseudoureas and related compounds
ES8604220A1 (en) Pyrimidoisoquinoline derivatives.
SE8804696L (en) DIOXAZOCIN DERIVATIVES, THEIR PREPARATION AND PREPARATIONS CONTAINING THEM
SE8300432D0 (en) REACTIVE CINNIC ACID DERIVATIVES FOR THE PREPARATION OF BIOLOGICALLY ACTIVE AMIDES
ES8401957A1 (en) Preparation of thiophene compounds
ES485835A1 (en) Thienylbenzoic-acid derivatives, process for their production, and pharmaceutical preparations containing these compounds.
ES465346A1 (en) 2h-imidazole-2-thione derivatives
ES459705A1 (en) Acylated hydrazinopyridazine antihypertensives
ES451820A1 (en) Production of tetrahydrobenzo *b* thienyl urea tetrahydroo77oxobenzo*b* thienyl urea and derivatives thereof
ES453718A1 (en) Process for preparing aminoethanols
ES449831A1 (en) A procedure for the preparation of new antibiotic derivatives xk62-2. (Machine-translation by Google Translate, not legally binding)

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20001009