ES8105391A1 - Un procedimiento para la preparacion de un vector de trans- ferencia. - Google Patents
Un procedimiento para la preparacion de un vector de trans- ferencia.Info
- Publication number
- ES8105391A1 ES8105391A1 ES492044A ES492044A ES8105391A1 ES 8105391 A1 ES8105391 A1 ES 8105391A1 ES 492044 A ES492044 A ES 492044A ES 492044 A ES492044 A ES 492044A ES 8105391 A1 ES8105391 A1 ES 8105391A1
- Authority
- ES
- Spain
- Prior art keywords
- growth hormone
- cloning
- therefor
- human pre
- transfer vector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 244000005700 microbiome Species 0.000 title abstract 3
- 108010057578 pregrowth hormone Proteins 0.000 title abstract 3
- 239000013598 vector Substances 0.000 title abstract 3
- 238000010367 cloning Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 108020004414 DNA Proteins 0.000 abstract 3
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/185—Escherichia
- C12R2001/19—Escherichia coli
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Plant Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE UN VECTOR DE TRANSFERENCIA DE D.N.A. CONSISTE EN HACER REACCIONAR UNA SECUENCIA DE DESOXINUCLEOTIDOS PARA LA HORMONA HUMANA DE PRECRECIMIENTO CON UNA MOLECULA D.N.A. PREPARADA MEDIANTE SEGMENTACION DE UN VECTOR DE TRANSFERENCIA CON UNA ENZIMA DE RESTRICCION. LA REACCION SE CATALIZA MEDIANTE UNA LIGASA DE D.N.A.; LOS VECTORES DE TRANSFERENCIA QUE SE PUEDEN OBTENER SON LOS PLASMIDOS PTRPED50-HGH Y PBR322/HGH800; LAS MOLECULAS ADN PREPARADAS POR SEGMENTACION DE UN VECTOR DE TRANSFERENCIA CON UNA ENZIMA DE RESTRICCION SON PTRPED50 Y PBR322; LA ENZIMA ES ENDONUCLEASA HIND III. TRATAMIENTO DE HEMORRAGIA GASTROINTESTINAL, CURACION DE FRACTURAS, ENFERMEDAD METABOLICA DE HUESOS Y CURACION DE HERIDAS. P
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4464779A | 1979-06-01 | 1979-06-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES492044A0 ES492044A0 (es) | 1981-05-16 |
ES8105391A1 true ES8105391A1 (es) | 1981-05-16 |
Family
ID=21933526
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES492044A Expired ES8105391A1 (es) | 1979-06-01 | 1980-05-30 | Un procedimiento para la preparacion de un vector de trans- ferencia. |
ES499046A Granted ES499046A0 (es) | 1979-06-01 | 1981-02-02 | Un procedimiento para clonar una secuencia de desoxinucleo- tidos |
ES499045A Granted ES499045A0 (es) | 1979-06-01 | 1981-02-02 | Un procedimiento para la preparacion de una proteina quimera |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES499046A Granted ES499046A0 (es) | 1979-06-01 | 1981-02-02 | Un procedimiento para clonar una secuencia de desoxinucleo- tidos |
ES499045A Granted ES499045A0 (es) | 1979-06-01 | 1981-02-02 | Un procedimiento para la preparacion de una proteina quimera |
Country Status (25)
Country | Link |
---|---|
EP (1) | EP0020147B2 (es) |
JP (1) | JPH0630582B2 (es) |
KR (1) | KR860001515B1 (es) |
AR (1) | AR248049A1 (es) |
AT (1) | ATE5978T1 (es) |
AU (1) | AU543917B2 (es) |
BG (1) | BG41134A3 (es) |
CA (1) | CA1194432A (es) |
DD (3) | DD202045A5 (es) |
DE (1) | DE3066256D1 (es) |
DK (1) | DK232980A (es) |
EG (1) | EG15156A (es) |
ES (3) | ES8105391A1 (es) |
FI (1) | FI801743A (es) |
GR (1) | GR68404B (es) |
HU (1) | HU196237B (es) |
IE (1) | IE50378B1 (es) |
IL (1) | IL60186A (es) |
NZ (1) | NZ193867A (es) |
PH (3) | PH21531A (es) |
PL (1) | PL224664A1 (es) |
PT (1) | PT71323A (es) |
RO (1) | RO79982A (es) |
YU (1) | YU145380A (es) |
ZA (1) | ZA802992B (es) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2052516B (en) * | 1979-06-01 | 1983-06-29 | Searle & Co | Plasmid vectors production and use thereof |
US4342832A (en) * | 1979-07-05 | 1982-08-03 | Genentech, Inc. | Method of constructing a replicable cloning vehicle having quasi-synthetic genes |
US4530901A (en) * | 1980-01-08 | 1985-07-23 | Biogen N.V. | Recombinant DNA molecules and their use in producing human interferon-like polypeptides |
US6835557B1 (en) | 1980-01-08 | 2004-12-28 | Biogen, Inc. | DNA sequences, recombinant DNA molecules and processes for producing human interferon-like polypeptides |
US4338397A (en) * | 1980-04-11 | 1982-07-06 | President And Fellows Of Harvard College | Mature protein synthesis |
GB2121048B (en) * | 1980-07-03 | 1984-06-06 | Genentech Inc | Microbial expression of quasi-synthetic genes |
IE52755B1 (en) * | 1980-08-26 | 1988-02-17 | Univ California | Bovine pre-growth and growth hormone |
US4775622A (en) * | 1982-03-08 | 1988-10-04 | Genentech, Inc. | Expression, processing and secretion of heterologous protein by yeast |
US4446235A (en) * | 1982-03-22 | 1984-05-01 | Genentech, Inc. | Method for cloning human growth hormone varient genes |
US4665160A (en) * | 1982-03-22 | 1987-05-12 | Genentech, Inc. | Novel human growth hormone like protein HGH-V encoded in the human genome |
US4508826A (en) * | 1982-04-15 | 1985-04-02 | Merck & Co., Inc. | Bacteriophage DNA cloning vector TG1 and microorganisms containing TG1 |
US4460689A (en) * | 1982-04-15 | 1984-07-17 | Merck & Co., Inc. | DNA Cloning vector TG1, derivatives, and processes of making |
DE3380262D1 (en) * | 1982-05-25 | 1989-08-31 | Lilly Co Eli | Cloning vectors for expression of exogenous protein |
CA1341012C (en) | 1982-09-27 | 2000-06-06 | Biogen, Inc. | Dna sequences, recombinant dna molecules and processes for producing swine growth hormone-like polypeptides |
FR2534273B1 (fr) * | 1982-10-07 | 1985-09-13 | Pasteur Institut | Lignees cellulaires originaires de mammiferes superieurs, productrices d'hormone de croissance, de preference humaine, et vecteurs pour leur obtention |
AU2092983A (en) * | 1982-11-08 | 1984-05-17 | Genentech Inc. | Porcine growth hormone produced by recombinant dna technology |
JPS6011557A (ja) * | 1983-04-19 | 1985-01-21 | ジエネツクス・コ−ポレイシヨン | クロ−ンヒツジ成長ホルモン遺伝子 |
US4755465A (en) * | 1983-04-25 | 1988-07-05 | Genentech, Inc. | Secretion of correctly processed human growth hormone in E. coli and Pseudomonas |
US4859600A (en) * | 1983-04-25 | 1989-08-22 | Genentech, Inc. | Recombinant procaryotic cell containing correctly processed human growth hormone |
ZA844380B (en) * | 1983-07-05 | 1985-01-30 | Salk Inst For Biological Studi | Dna encoding a grf precursor |
BG49718A3 (en) * | 1983-07-15 | 1992-01-15 | Bio Technology General Corp | Method for preparing of polypeptid with superoxiddismutasne activitty |
IL78775A (en) * | 1985-05-15 | 1992-06-21 | Biotech Australia Pty Ltd | Oral vaccines |
DE3526995A1 (de) * | 1985-07-27 | 1987-02-05 | Hoechst Ag | Fusionsproteine, verfahren zu ihrer herstellung und ihre verwendung |
JP2500312B2 (ja) * | 1986-01-13 | 1996-05-29 | 工業技術院長 | ヒト成長ホルモンの生産法 |
FR2599753B1 (fr) * | 1986-06-05 | 1989-12-08 | Sanofi Sa | Sequence d'adn composite et son application pour la production de l'hormone de croissance |
ATE386811T1 (de) | 1996-04-05 | 2008-03-15 | Novartis Vaccines & Diagnostic | Alphaviren-vektors mit eine reduzierte inhibierung der synthese von zellmakromolekülen |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ187300A (en) * | 1977-05-27 | 1982-08-17 | Univ California | Dna transfer vector and micro-organism modified to contain a nucleotide sequence equivalent to the gene of a higher organism |
ZA782933B (en) * | 1977-09-23 | 1979-05-30 | Univ California | Purification of nucleotide sequences suitable for expression in bacteria |
YU257278A (en) * | 1977-11-08 | 1984-02-29 | Genentech Inc | Process for obtaining a recombinat clone carrier |
IE48385B1 (en) * | 1978-08-11 | 1984-12-26 | Univ California | Synthesis of a eucaryotic protein by a microorganism |
-
1980
- 1980-05-20 ZA ZA00802992A patent/ZA802992B/xx unknown
- 1980-05-20 GR GR62003A patent/GR68404B/el unknown
- 1980-05-28 NZ NZ193867A patent/NZ193867A/xx unknown
- 1980-05-28 PH PH24077A patent/PH21531A/en unknown
- 1980-05-29 AR AR80281231A patent/AR248049A1/es active
- 1980-05-29 AT AT80301785T patent/ATE5978T1/de active
- 1980-05-29 EP EP80301785A patent/EP0020147B2/en not_active Expired
- 1980-05-29 DE DE8080301785T patent/DE3066256D1/de not_active Expired
- 1980-05-29 IL IL60186A patent/IL60186A/xx unknown
- 1980-05-29 PT PT71323A patent/PT71323A/pt not_active IP Right Cessation
- 1980-05-29 FI FI801743A patent/FI801743A/fi not_active Application Discontinuation
- 1980-05-30 BG BG8047972A patent/BG41134A3/xx unknown
- 1980-05-30 DK DK232980A patent/DK232980A/da not_active Application Discontinuation
- 1980-05-30 IE IE1137/80A patent/IE50378B1/en not_active IP Right Cessation
- 1980-05-30 YU YU01453/80A patent/YU145380A/xx unknown
- 1980-05-30 HU HU801371A patent/HU196237B/hu not_active IP Right Cessation
- 1980-05-30 ES ES492044A patent/ES8105391A1/es not_active Expired
- 1980-05-30 AU AU58926/80A patent/AU543917B2/en not_active Expired
- 1980-05-30 CA CA000353090A patent/CA1194432A/en not_active Expired
- 1980-05-31 KR KR1019800002178A patent/KR860001515B1/ko active
- 1980-05-31 EG EG337/80A patent/EG15156A/xx active
- 1980-05-31 PL PL22466480A patent/PL224664A1/xx unknown
- 1980-05-31 RO RO80101293A patent/RO79982A/ro unknown
- 1980-06-02 DD DD80234741A patent/DD202045A5/de unknown
- 1980-06-02 DD DD80234739A patent/DD202046A5/de unknown
- 1980-06-02 JP JP55074122A patent/JPH0630582B2/ja not_active Expired - Lifetime
- 1980-06-02 DD DD80221521A patent/DD154022A5/de not_active IP Right Cessation
-
1981
- 1981-02-02 ES ES499046A patent/ES499046A0/es active Granted
- 1981-02-02 ES ES499045A patent/ES499045A0/es active Granted
-
1982
- 1982-11-05 PH PH28092A patent/PH21939A/en unknown
-
1985
- 1985-01-24 PH PH31764A patent/PH22089A/en unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19980202 |