AR248049A1 - Un vector recombinante de transferencia de dna util para la expresion de la hormona de crecimiento humano. - Google Patents
Un vector recombinante de transferencia de dna util para la expresion de la hormona de crecimiento humano.Info
- Publication number
- AR248049A1 AR248049A1 AR80281231A AR28123180A AR248049A1 AR 248049 A1 AR248049 A1 AR 248049A1 AR 80281231 A AR80281231 A AR 80281231A AR 28123180 A AR28123180 A AR 28123180A AR 248049 A1 AR248049 A1 AR 248049A1
- Authority
- AR
- Argentina
- Prior art keywords
- growth hormone
- dna transfer
- cloning
- therefor
- transfer vector
- Prior art date
Links
- 244000005700 microbiome Species 0.000 title abstract 2
- 238000010367 cloning Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 108010057578 pregrowth hormone Proteins 0.000 title 1
- 102000002265 Human Growth Hormone Human genes 0.000 abstract 1
- 108010000521 Human Growth Hormone Proteins 0.000 abstract 1
- 239000000854 Human Growth Hormone Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/185—Escherichia
- C12R2001/19—Escherichia coli
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Plant Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
Abstract
UN VECTOR RECOMBINANTE DE TRANSFERENCIA DE DNA UTIL PARA LA EXPRESION DE LA HORMONA DE CRECIMIENTO HUMANA, QUE CONTIENE UNA SECUENCIA NUCLEOTIDICA QUE COMPRENDE UN VECTOR PLASMIDICO O BACTERIOFAGO PBR322 O PTRPED5-1, Y DENTRO DE SU SECUENCIA NUCLEOTIDICA UN CODIGO DE SUBSECUENCIA PARA HORMONA DE CRECIMIENTO HUMANA, QUE ESTA INSERTADA DENTRO DE PBR322 EN EL SITIO DE RESTRICCION PST I, HIND III, SAL I, BAM HI O ECO RI, Y DENTRO DE PTRPED5-1 EN EL SITIO DE RESTRICCION HIND III; Y UNIDA A LA SECUENCIA DEL VECTOR DE TRANSFERENCIA MEDIANTE LIGADURAS DE FOSFODIESTER, SIENDO EL VECTOR RECOMBINANTE TRANSFERIBLE Y REPICABLE EN UNA CEPA DE MICROORGANISMO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4464779A | 1979-06-01 | 1979-06-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR248049A1 true AR248049A1 (es) | 1995-05-31 |
Family
ID=21933526
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR80281231A AR248049A1 (es) | 1979-06-01 | 1980-05-29 | Un vector recombinante de transferencia de dna util para la expresion de la hormona de crecimiento humano. |
Country Status (25)
Country | Link |
---|---|
EP (1) | EP0020147B2 (es) |
JP (1) | JPH0630582B2 (es) |
KR (1) | KR860001515B1 (es) |
AR (1) | AR248049A1 (es) |
AT (1) | ATE5978T1 (es) |
AU (1) | AU543917B2 (es) |
BG (1) | BG41134A3 (es) |
CA (1) | CA1194432A (es) |
DD (3) | DD202045A5 (es) |
DE (1) | DE3066256D1 (es) |
DK (1) | DK232980A (es) |
EG (1) | EG15156A (es) |
ES (3) | ES492044A0 (es) |
FI (1) | FI801743A (es) |
GR (1) | GR68404B (es) |
HU (1) | HU196237B (es) |
IE (1) | IE50378B1 (es) |
IL (1) | IL60186A (es) |
NZ (1) | NZ193867A (es) |
PH (3) | PH21531A (es) |
PL (1) | PL224664A1 (es) |
PT (1) | PT71323A (es) |
RO (1) | RO79982A (es) |
YU (1) | YU145380A (es) |
ZA (1) | ZA802992B (es) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2052516B (en) * | 1979-06-01 | 1983-06-29 | Searle & Co | Plasmid vectors production and use thereof |
US4342832A (en) * | 1979-07-05 | 1982-08-03 | Genentech, Inc. | Method of constructing a replicable cloning vehicle having quasi-synthetic genes |
US6835557B1 (en) | 1980-01-08 | 2004-12-28 | Biogen, Inc. | DNA sequences, recombinant DNA molecules and processes for producing human interferon-like polypeptides |
US4530901A (en) * | 1980-01-08 | 1985-07-23 | Biogen N.V. | Recombinant DNA molecules and their use in producing human interferon-like polypeptides |
US4338397A (en) * | 1980-04-11 | 1982-07-06 | President And Fellows Of Harvard College | Mature protein synthesis |
GB2121048B (en) * | 1980-07-03 | 1984-06-06 | Genentech Inc | Microbial expression of quasi-synthetic genes |
IE52755B1 (en) * | 1980-08-26 | 1988-02-17 | Univ California | Bovine pre-growth and growth hormone |
US4775622A (en) * | 1982-03-08 | 1988-10-04 | Genentech, Inc. | Expression, processing and secretion of heterologous protein by yeast |
US4665160A (en) * | 1982-03-22 | 1987-05-12 | Genentech, Inc. | Novel human growth hormone like protein HGH-V encoded in the human genome |
US4446235A (en) * | 1982-03-22 | 1984-05-01 | Genentech, Inc. | Method for cloning human growth hormone varient genes |
US4508826A (en) * | 1982-04-15 | 1985-04-02 | Merck & Co., Inc. | Bacteriophage DNA cloning vector TG1 and microorganisms containing TG1 |
US4460689A (en) * | 1982-04-15 | 1984-07-17 | Merck & Co., Inc. | DNA Cloning vector TG1, derivatives, and processes of making |
GB2121054B (en) * | 1982-05-25 | 1986-02-26 | Lilly Co Eli | Cloning vectors for expression of exogenous protein |
CA1341012C (en) | 1982-09-27 | 2000-06-06 | Biogen, Inc. | Dna sequences, recombinant dna molecules and processes for producing swine growth hormone-like polypeptides |
FR2534273B1 (fr) * | 1982-10-07 | 1985-09-13 | Pasteur Institut | Lignees cellulaires originaires de mammiferes superieurs, productrices d'hormone de croissance, de preference humaine, et vecteurs pour leur obtention |
AU2092983A (en) * | 1982-11-08 | 1984-05-17 | Genentech Inc. | Porcine growth hormone produced by recombinant dna technology |
AU2704084A (en) * | 1983-04-19 | 1984-10-25 | Genex Corp. | Cloned ovine growth hormone genes |
US4755465A (en) * | 1983-04-25 | 1988-07-05 | Genentech, Inc. | Secretion of correctly processed human growth hormone in E. coli and Pseudomonas |
US4859600A (en) * | 1983-04-25 | 1989-08-22 | Genentech, Inc. | Recombinant procaryotic cell containing correctly processed human growth hormone |
ZA844380B (en) * | 1983-07-05 | 1985-01-30 | Salk Inst For Biological Studi | Dna encoding a grf precursor |
BG49718A3 (en) * | 1983-07-15 | 1992-01-15 | Bio Technology General Corp | Method for preparing of polypeptid with superoxiddismutasne activitty |
IL78775A (en) * | 1985-05-15 | 1992-06-21 | Biotech Australia Pty Ltd | Oral vaccines |
DE3526995A1 (de) * | 1985-07-27 | 1987-02-05 | Hoechst Ag | Fusionsproteine, verfahren zu ihrer herstellung und ihre verwendung |
JP2500312B2 (ja) * | 1986-01-13 | 1996-05-29 | 工業技術院長 | ヒト成長ホルモンの生産法 |
FR2599753B1 (fr) * | 1986-06-05 | 1989-12-08 | Sanofi Sa | Sequence d'adn composite et son application pour la production de l'hormone de croissance |
JP4383530B2 (ja) | 1996-04-05 | 2009-12-16 | ノバルティス バクシンズ アンド ダイアグノスティックス, インコーポレーテッド | 細胞巨大分子合成の阻害が減少したアルファウイルスベクター |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ187300A (en) * | 1977-05-27 | 1982-08-17 | Univ California | Dna transfer vector and micro-organism modified to contain a nucleotide sequence equivalent to the gene of a higher organism |
ZA782933B (en) * | 1977-09-23 | 1979-05-30 | Univ California | Purification of nucleotide sequences suitable for expression in bacteria |
ES474852A1 (es) * | 1977-11-08 | 1979-12-01 | Genentech Inc | Un metodo para la expresion,en un huesped bacteriano trans- formado de un polipeptido heterologo con respecto al huespeden su estado no transformado |
IE48385B1 (en) * | 1978-08-11 | 1984-12-26 | Univ California | Synthesis of a eucaryotic protein by a microorganism |
-
1980
- 1980-05-20 ZA ZA00802992A patent/ZA802992B/xx unknown
- 1980-05-20 GR GR62003A patent/GR68404B/el unknown
- 1980-05-28 PH PH24077A patent/PH21531A/en unknown
- 1980-05-28 NZ NZ193867A patent/NZ193867A/xx unknown
- 1980-05-29 EP EP80301785A patent/EP0020147B2/en not_active Expired
- 1980-05-29 FI FI801743A patent/FI801743A/fi not_active Application Discontinuation
- 1980-05-29 PT PT71323A patent/PT71323A/pt not_active IP Right Cessation
- 1980-05-29 AT AT80301785T patent/ATE5978T1/de active
- 1980-05-29 AR AR80281231A patent/AR248049A1/es active
- 1980-05-29 IL IL60186A patent/IL60186A/xx unknown
- 1980-05-29 DE DE8080301785T patent/DE3066256D1/de not_active Expired
- 1980-05-30 IE IE1137/80A patent/IE50378B1/en not_active IP Right Cessation
- 1980-05-30 HU HU801371A patent/HU196237B/hu not_active IP Right Cessation
- 1980-05-30 CA CA000353090A patent/CA1194432A/en not_active Expired
- 1980-05-30 BG BG8047972A patent/BG41134A3/xx unknown
- 1980-05-30 YU YU01453/80A patent/YU145380A/xx unknown
- 1980-05-30 DK DK232980A patent/DK232980A/da not_active Application Discontinuation
- 1980-05-30 ES ES492044A patent/ES492044A0/es active Granted
- 1980-05-30 AU AU58926/80A patent/AU543917B2/en not_active Expired
- 1980-05-31 RO RO80101293A patent/RO79982A/ro unknown
- 1980-05-31 KR KR1019800002178A patent/KR860001515B1/ko active
- 1980-05-31 EG EG337/80A patent/EG15156A/xx active
- 1980-05-31 PL PL22466480A patent/PL224664A1/xx unknown
- 1980-06-02 JP JP55074122A patent/JPH0630582B2/ja not_active Expired - Lifetime
- 1980-06-02 DD DD80234741A patent/DD202045A5/de unknown
- 1980-06-02 DD DD80221521A patent/DD154022A5/de not_active IP Right Cessation
- 1980-06-02 DD DD80234739A patent/DD202046A5/de unknown
-
1981
- 1981-02-02 ES ES499046A patent/ES8202586A1/es not_active Expired
- 1981-02-02 ES ES499045A patent/ES8202588A1/es not_active Expired
-
1982
- 1982-11-05 PH PH28092A patent/PH21939A/en unknown
-
1985
- 1985-01-24 PH PH31764A patent/PH22089A/en unknown
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