ES8103043A1 - Procedimiento para la obtencion de derivados de 2-hidroxime-til-3,4,5-trihidroxipiperidinas - Google Patents

Procedimiento para la obtencion de derivados de 2-hidroxime-til-3,4,5-trihidroxipiperidinas

Info

Publication number
ES8103043A1
ES8103043A1 ES492821A ES492821A ES8103043A1 ES 8103043 A1 ES8103043 A1 ES 8103043A1 ES 492821 A ES492821 A ES 492821A ES 492821 A ES492821 A ES 492821A ES 8103043 A1 ES8103043 A1 ES 8103043A1
Authority
ES
Spain
Prior art keywords
hydroxymethyl
alkadien
piperidines
trihydroxy
medicaments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES492821A
Other languages
English (en)
Other versions
ES492821A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES8103043A1 publication Critical patent/ES8103043A1/es
Publication of ES492821A0 publication Critical patent/ES492821A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

OBTENCION DE DERIVADOS DE 2-HIDROXIMETIL-3,4,5-TRIHIDROXIPIPERIDINAS DE FORMULA: *FORMULA* DONDE <N> REPRESENTA UN NUMERO ENTRE 0 Y 5. SE CARACTERIZA PORQUE 1-DESOXIMOJIRIMICINA SE ALQUILA REDUCTIVAMENTE EN PRESENCIA DE UN DONADOR DE H2 CON UN ALDEHIDO DE FORMULA: OCH-(CH=CH(N-H. ESTOS DERIVADOS SE EMPLEAN COMO MEDICAMENTOS, ESPECIALMENTE CONTRA DIABETES, HIPERLIPROTENEMIA, ATEROESCLEROSIS Y ADIPOSITAS.
ES492821A 1979-06-27 1980-06-26 Procedimiento para la obtencion de derivados de 2-hidroxime-til-3,4,5-trihidroxipiperidinas Granted ES492821A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792925943 DE2925943A1 (de) 1979-06-27 1979-06-27 1-alkadien-2,4-yl-2-hydroxymethyl3,4,5-trihydroxypiperidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
ES8103043A1 true ES8103043A1 (es) 1981-02-16
ES492821A0 ES492821A0 (es) 1981-02-16

Family

ID=6074298

Family Applications (1)

Application Number Title Priority Date Filing Date
ES492821A Granted ES492821A0 (es) 1979-06-27 1980-06-26 Procedimiento para la obtencion de derivados de 2-hidroxime-til-3,4,5-trihidroxipiperidinas

Country Status (16)

Country Link
US (1) US4312872A (es)
EP (1) EP0022192B1 (es)
JP (1) JPS6026388B2 (es)
AT (1) ATE3421T1 (es)
AU (1) AU5933080A (es)
CA (1) CA1138879A (es)
DE (2) DE2925943A1 (es)
DK (1) DK274980A (es)
ES (1) ES492821A0 (es)
FI (1) FI802023A (es)
GR (1) GR69296B (es)
HU (1) HU180149B (es)
IL (1) IL60382A0 (es)
NO (1) NO801731L (es)
PT (1) PT71408A (es)
ZA (1) ZA803818B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56108767A (en) * 1980-01-28 1981-08-28 Nippon Shinyaku Co Ltd Bismoranoline derivative
DE3507019A1 (de) * 1985-02-28 1986-08-28 Bayer Ag, 5090 Leverkusen Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung
US4690486A (en) * 1985-04-29 1987-09-01 Texas Instruments Incorporated Four position interlacing apparatus
US4837026A (en) * 1985-10-03 1989-06-06 Rajakhyaksha Vithal J Transdermal and systemic preparation and method
US5192772A (en) * 1987-12-09 1993-03-09 Nippon Shinyaku Co. Ltd. Therapeutic agents
GB8827701D0 (en) * 1987-12-09 1988-12-29 Nippon Shinyaku Co Ltd Thrombolytic &c compositions
JPH0369383U (es) * 1989-11-01 1991-07-10
US5252587A (en) * 1990-04-27 1993-10-12 Merrell Dow Pharmaceuticals, Inc. N-derivatives of 1-deoxy nojirimycin
US5536732A (en) * 1990-04-27 1996-07-16 Merrell Pharmaceuticals Inc. N-derivatives of 1-deoxy nojirimycin
JP2640897B2 (ja) * 1992-11-16 1997-08-13 中央紙器工業株式会社 板状材梱包用の段ボール製パッキン
US5863903A (en) * 1994-03-09 1999-01-26 Novo Nordisk A/S Use of hydroxy alkyl piperidine and pyrrolidine compounds to treat diabetes
AU1890295A (en) * 1994-03-09 1995-09-25 Novo Nordisk A/S Piperidines and pyrrolidines
ATE322900T1 (de) * 1996-07-15 2006-04-15 Macrozyme Dnm B V Deoxynojirimycin derivate und ihre verwendung als glukosesylceramidase-inhibitoren

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1555654A (en) * 1977-06-25 1979-11-14 Exxon Research Engineering Co Agricultural burner apparatus
NO154918C (no) * 1977-08-27 1987-01-14 Bayer Ag Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.
JPS5943946B2 (ja) * 1978-04-28 1984-10-25 日本新薬株式会社 Ｎ−アルケニルモラノリン誘導体
GB2020278B (en) * 1978-05-03 1983-02-23 Nippon Shinyaku Co Ltd Moranoline dervitives
DE2830469A1 (de) * 1978-07-11 1980-01-24 Bayer Ag Herstellung von l-desoxy-nojirimycin und n-substituierten derivaten

Also Published As

Publication number Publication date
DK274980A (da) 1980-12-28
NO801731L (no) 1980-12-29
AU5933080A (en) 1981-01-08
DE2925943A1 (de) 1981-01-29
EP0022192B1 (de) 1983-05-18
DE3063301D1 (en) 1983-07-07
ATE3421T1 (de) 1983-06-15
JPS6026388B2 (ja) 1985-06-24
EP0022192A1 (de) 1981-01-14
JPS567763A (en) 1981-01-27
IL60382A0 (en) 1980-09-16
FI802023A (fi) 1980-12-28
HU180149B (en) 1983-02-28
CA1138879A (en) 1983-01-04
PT71408A (de) 1980-07-01
US4312872A (en) 1982-01-26
ES492821A0 (es) 1981-02-16
GR69296B (es) 1982-05-13
ZA803818B (en) 1981-07-29

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