ZA803818B - New 1-alka-2,4-dienyl-2-hydroxymethyl-3,4,5-trihydroxypipeidine compounds, the production and their medicinal use - Google Patents

New 1-alka-2,4-dienyl-2-hydroxymethyl-3,4,5-trihydroxypipeidine compounds, the production and their medicinal use

Info

Publication number
ZA803818B
ZA803818B ZA00803818A ZA803818A ZA803818B ZA 803818 B ZA803818 B ZA 803818B ZA 00803818 A ZA00803818 A ZA 00803818A ZA 803818 A ZA803818 A ZA 803818A ZA 803818 B ZA803818 B ZA 803818B
Authority
ZA
South Africa
Prior art keywords
compounds
alka
dienyl
hydroxymethyl
trihydroxypipeidine
Prior art date
Application number
ZA00803818A
Other languages
English (en)
Inventor
W Puls
R Sitt
B Junge
H Krause
L Mueller
Guenter Thomas
Thomas Guenter
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA803818B publication Critical patent/ZA803818B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/46Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA00803818A 1979-06-27 1980-06-26 New 1-alka-2,4-dienyl-2-hydroxymethyl-3,4,5-trihydroxypipeidine compounds, the production and their medicinal use ZA803818B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792925943 DE2925943A1 (de) 1979-06-27 1979-06-27 1-alkadien-2,4-yl-2-hydroxymethyl3,4,5-trihydroxypiperidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
ZA803818B true ZA803818B (en) 1981-07-29

Family

ID=6074298

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00803818A ZA803818B (en) 1979-06-27 1980-06-26 New 1-alka-2,4-dienyl-2-hydroxymethyl-3,4,5-trihydroxypipeidine compounds, the production and their medicinal use

Country Status (16)

Country Link
US (1) US4312872A (xx)
EP (1) EP0022192B1 (xx)
JP (1) JPS6026388B2 (xx)
AT (1) ATE3421T1 (xx)
AU (1) AU5933080A (xx)
CA (1) CA1138879A (xx)
DE (2) DE2925943A1 (xx)
DK (1) DK274980A (xx)
ES (1) ES8103043A1 (xx)
FI (1) FI802023A (xx)
GR (1) GR69296B (xx)
HU (1) HU180149B (xx)
IL (1) IL60382A0 (xx)
NO (1) NO801731L (xx)
PT (1) PT71408A (xx)
ZA (1) ZA803818B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56108767A (en) * 1980-01-28 1981-08-28 Nippon Shinyaku Co Ltd Bismoranoline derivative
DE3507019A1 (de) * 1985-02-28 1986-08-28 Bayer Ag, 5090 Leverkusen Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung
US4690486A (en) * 1985-04-29 1987-09-01 Texas Instruments Incorporated Four position interlacing apparatus
US4837026A (en) * 1985-10-03 1989-06-06 Rajakhyaksha Vithal J Transdermal and systemic preparation and method
GB8827701D0 (en) * 1987-12-09 1988-12-29 Nippon Shinyaku Co Ltd Thrombolytic &c compositions
US5192772A (en) * 1987-12-09 1993-03-09 Nippon Shinyaku Co. Ltd. Therapeutic agents
JPH0369383U (xx) * 1989-11-01 1991-07-10
US5536732A (en) * 1990-04-27 1996-07-16 Merrell Pharmaceuticals Inc. N-derivatives of 1-deoxy nojirimycin
US5252587A (en) * 1990-04-27 1993-10-12 Merrell Dow Pharmaceuticals, Inc. N-derivatives of 1-deoxy nojirimycin
JP2640897B2 (ja) * 1992-11-16 1997-08-13 中央紙器工業株式会社 板状材梱包用の段ボール製パッキン
WO1995024391A1 (en) * 1994-03-09 1995-09-14 Novo Nordisk A/S Piperidines and pyrrolidines
US5863903A (en) * 1994-03-09 1999-01-26 Novo Nordisk A/S Use of hydroxy alkyl piperidine and pyrrolidine compounds to treat diabetes
IL128036A (en) * 1996-07-15 2005-08-31 Univ Amsterdam Deoxynojirimycin derivatives comprising a polyclic alcohol group, pharmaceutical composition comprising a deoxynojirimycin derivative and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1555654A (en) * 1977-06-25 1979-11-14 Exxon Research Engineering Co Agricultural burner apparatus
NO154918C (no) * 1977-08-27 1987-01-14 Bayer Ag Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.
JPS5943946B2 (ja) * 1978-04-28 1984-10-25 日本新薬株式会社 N−アルケニルモラノリン誘導体
GB2020278B (en) * 1978-05-03 1983-02-23 Nippon Shinyaku Co Ltd Moranoline dervitives
DE2830469A1 (de) * 1978-07-11 1980-01-24 Bayer Ag Herstellung von l-desoxy-nojirimycin und n-substituierten derivaten

Also Published As

Publication number Publication date
PT71408A (de) 1980-07-01
CA1138879A (en) 1983-01-04
FI802023A (fi) 1980-12-28
IL60382A0 (en) 1980-09-16
DK274980A (da) 1980-12-28
DE2925943A1 (de) 1981-01-29
EP0022192B1 (de) 1983-05-18
ES492821A0 (es) 1981-02-16
DE3063301D1 (en) 1983-07-07
AU5933080A (en) 1981-01-08
ATE3421T1 (de) 1983-06-15
EP0022192A1 (de) 1981-01-14
HU180149B (en) 1983-02-28
GR69296B (xx) 1982-05-13
JPS6026388B2 (ja) 1985-06-24
ES8103043A1 (es) 1981-02-16
US4312872A (en) 1982-01-26
JPS567763A (en) 1981-01-27
NO801731L (no) 1980-12-29

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