ES8101552A1 - Procedimiento para la produccion de esteres de fenoles sustituidos - Google Patents
Procedimiento para la produccion de esteres de fenoles sustituidosInfo
- Publication number
- ES8101552A1 ES8101552A1 ES488345A ES488345A ES8101552A1 ES 8101552 A1 ES8101552 A1 ES 8101552A1 ES 488345 A ES488345 A ES 488345A ES 488345 A ES488345 A ES 488345A ES 8101552 A1 ES8101552 A1 ES 8101552A1
- Authority
- ES
- Spain
- Prior art keywords
- cycloalkyl
- hydrogen
- clofibric
- acid esters
- nicotinic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003315 2-(4-chlorophenoxy)-2-methylpropanoic acid Substances 0.000 title 1
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical class OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 title 1
- TXCGAZHTZHNUAI-UHFFFAOYSA-N clofibric acid Chemical compound OC(=O)C(C)(C)OC1=CC=C(Cl)C=C1 TXCGAZHTZHNUAI-UHFFFAOYSA-N 0.000 title 1
- 229950008441 clofibric acid Drugs 0.000 title 1
- -1 2-(4- chlorophenoxy)-2-methyl-propyl Chemical group 0.000 abstract 7
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 6
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000000242 4-chlorobenzoyl group Chemical group ClC1=CC=C(C(=O)*)C=C1 0.000 abstract 1
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract 1
- KPCZJLGGXRGYIE-UHFFFAOYSA-N [C]1=CC=CN=C1 Chemical group [C]1=CC=CN=C1 KPCZJLGGXRGYIE-UHFFFAOYSA-N 0.000 abstract 1
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000000587 piperidin-1-yl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 125000000246 pyrimidin-2-yl group Chemical group [H]C1=NC(*)=NC([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2904757 | 1979-02-08 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES488345A0 ES488345A0 (es) | 1980-12-16 |
| ES8101552A1 true ES8101552A1 (es) | 1980-12-16 |
Family
ID=6062456
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES488345A Expired ES8101552A1 (es) | 1979-02-08 | 1980-02-07 | Procedimiento para la produccion de esteres de fenoles sustituidos |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS55129245A (zh) |
| AR (1) | AR228251A1 (zh) |
| AT (1) | AT374797B (zh) |
| AU (1) | AU532208B2 (zh) |
| BE (1) | BE881626A (zh) |
| CA (1) | CA1135689A (zh) |
| CH (1) | CH644092A5 (zh) |
| DK (1) | DK152360C (zh) |
| ES (1) | ES8101552A1 (zh) |
| FR (1) | FR2448532A1 (zh) |
| GB (1) | GB2041937B (zh) |
| GR (1) | GR73905B (zh) |
| HU (1) | HU182099B (zh) |
| IE (1) | IE49385B1 (zh) |
| IL (1) | IL59337A (zh) |
| IT (1) | IT1141197B (zh) |
| MX (1) | MX6377E (zh) |
| NL (1) | NL8000826A (zh) |
| PL (1) | PL123379B1 (zh) |
| SE (1) | SE450381B (zh) |
| SG (1) | SG51185G (zh) |
| YU (1) | YU33880A (zh) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3891219T1 (de) * | 1988-01-22 | 1990-02-01 | Kh Nii Endokrinologii I Chimii | P-chlorphenoxysobuttersaeureundezylester und arzneimittel auf dessen grundlage zur behandlung der hyperlipidaemie |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3175M (fr) * | 1963-06-25 | 1965-03-08 | Analyses Et De Rech S Biolog M | Nouveaux composés chimiques a action vaso-dilatatrice périphérique. |
| DE2352012A1 (de) * | 1972-11-01 | 1974-05-09 | Ciba Geigy Ag | Neue aliphatisch substituierte arylchalkogeno-kohlenwasserstoffderivate und verfahren zu ihrer herstellung |
| ES438246A1 (es) * | 1975-06-04 | 1977-01-16 | Alter Sa | Un procedimiento de preparacion del glicol 2-(p-clorofenoci)-2-metilpropinato nicotinato. |
| JPS57102866A (en) * | 1980-12-19 | 1982-06-26 | Kyorin Pharmaceut Co Ltd | Nicotinic acid derivative and its preparation |
-
1980
- 1980-02-06 SE SE8000962A patent/SE450381B/sv not_active IP Right Cessation
- 1980-02-07 IL IL59337A patent/IL59337A/xx not_active IP Right Cessation
- 1980-02-07 DK DK053680A patent/DK152360C/da not_active IP Right Cessation
- 1980-02-07 ES ES488345A patent/ES8101552A1/es not_active Expired
- 1980-02-07 IE IE236/80A patent/IE49385B1/en not_active IP Right Cessation
- 1980-02-07 MX MX808635U patent/MX6377E/es unknown
- 1980-02-08 NL NL8000826A patent/NL8000826A/nl not_active Application Discontinuation
- 1980-02-08 GR GR61163A patent/GR73905B/el unknown
- 1980-02-08 YU YU00338/80A patent/YU33880A/xx unknown
- 1980-02-08 GB GB8004310A patent/GB2041937B/en not_active Expired
- 1980-02-08 BE BE0/199326A patent/BE881626A/fr not_active IP Right Cessation
- 1980-02-08 AU AU55355/80A patent/AU532208B2/en not_active Ceased
- 1980-02-08 CH CH106380A patent/CH644092A5/de active IP Right Maintenance
- 1980-02-08 IT IT19782/80A patent/IT1141197B/it active
- 1980-02-08 AT AT0070380A patent/AT374797B/de not_active IP Right Cessation
- 1980-02-08 JP JP1374980A patent/JPS55129245A/ja active Granted
- 1980-02-08 HU HU80289A patent/HU182099B/hu not_active IP Right Cessation
- 1980-02-08 PL PL1980221888A patent/PL123379B1/pl unknown
- 1980-02-08 CA CA000345303A patent/CA1135689A/en not_active Expired
- 1980-02-08 AR AR279916A patent/AR228251A1/es active
- 1980-02-08 FR FR8002783A patent/FR2448532A1/fr active Granted
-
1985
- 1985-06-27 SG SG511/85A patent/SG51185G/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK53680A (da) | 1980-08-09 |
| GB2041937B (en) | 1983-04-13 |
| BE881626A (fr) | 1980-08-08 |
| AR228251A1 (es) | 1983-02-15 |
| GR73905B (zh) | 1984-05-21 |
| IL59337A (en) | 1984-10-31 |
| ES488345A0 (es) | 1980-12-16 |
| IE49385B1 (en) | 1985-10-02 |
| SG51185G (en) | 1986-01-24 |
| DK152360B (da) | 1988-02-22 |
| AT374797B (de) | 1984-05-25 |
| JPS55129245A (en) | 1980-10-06 |
| HU182099B (en) | 1983-12-28 |
| YU33880A (en) | 1983-06-30 |
| FR2448532A1 (fr) | 1980-09-05 |
| MX6377E (es) | 1985-05-23 |
| AU532208B2 (en) | 1983-09-22 |
| DK152360C (da) | 1988-08-01 |
| IT8019782A0 (it) | 1980-02-08 |
| ATA70380A (de) | 1983-10-15 |
| PL221888A1 (zh) | 1980-10-20 |
| CA1135689A (en) | 1982-11-16 |
| IT1141197B (it) | 1986-10-01 |
| GB2041937A (en) | 1980-09-17 |
| JPS6126993B2 (zh) | 1986-06-23 |
| NL8000826A (nl) | 1980-08-12 |
| SE8000962L (sv) | 1980-08-09 |
| PL123379B1 (en) | 1982-10-30 |
| AU5535580A (en) | 1980-08-14 |
| FR2448532B1 (zh) | 1984-12-14 |
| SE450381B (sv) | 1987-06-22 |
| IE800236L (en) | 1980-08-08 |
| CH644092A5 (de) | 1984-07-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970519 |