ES8506620A1 - Un procedimiento para la preparacion de nuevos derivados de pirrol-2-acetilaminoacido - Google Patents

Un procedimiento para la preparacion de nuevos derivados de pirrol-2-acetilaminoacido

Info

Publication number
ES8506620A1
ES8506620A1 ES535101A ES535101A ES8506620A1 ES 8506620 A1 ES8506620 A1 ES 8506620A1 ES 535101 A ES535101 A ES 535101A ES 535101 A ES535101 A ES 535101A ES 8506620 A1 ES8506620 A1 ES 8506620A1
Authority
ES
Spain
Prior art keywords
compounds
pyrrole
utility
acid derivatives
inflammatory
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES535101A
Other languages
English (en)
Other versions
ES535101A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceuticals Inc
Original Assignee
McNeilab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/461,055 external-priority patent/US4585784A/en
Application filed by McNeilab Inc filed Critical McNeilab Inc
Publication of ES8506620A1 publication Critical patent/ES8506620A1/es
Publication of ES535101A0 publication Critical patent/ES535101A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE NUEVOS DERIVADOS DE PIRROL-2-ACETILAMINOACIDO.CONSISTE EN HACER REACCIONAR UN HALURO DE ACIDO DE FORMULA (II) CON UN AMINOACIDO DE FORMULA (III), EN PRESENCIA DE UNA BASE COMO BICARBONATO SODICO O POTASICO, Y EN SOLUCION ACUOSA PARA PREPARAR DERIVADOS DE PIRROL-E-ACETILAMINOACIDO O UNA SAL DEL MISMO DE FORMULA (I), DONDE RL ES H, ALQUILO C 1 A 6, (CH2)NCO2H, CH2CH2SCH3, (CH2)4) O (CH2)2CONH2; N ES 1 O 2; E Y ES H Y Q ES CH3 E Y ES CH3 Y Q ES C 1.TIENEN PROPIEDADES FARMACEUTICAS POR SU ACTIVIDAD ANALGESICA Y ANTIINFLAMATORIA, DISMINUYENDO LA IRRITACION GASTROINTESTINAL CON RELACION AL ZOMEPIRAC.
ES535101A 1983-01-26 1984-08-10 Un procedimiento para la preparacion de nuevos derivados de pirrol-2-acetilaminoacido Granted ES535101A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46104783A 1983-01-26 1983-01-26
US06/461,055 US4585784A (en) 1983-01-26 1983-01-26 Pyrrole-2-acetylamino acid derivative compounds

Publications (2)

Publication Number Publication Date
ES8506620A1 true ES8506620A1 (es) 1985-07-16
ES535101A0 ES535101A0 (es) 1985-07-16

Family

ID=27039899

Family Applications (2)

Application Number Title Priority Date Filing Date
ES529120A Expired ES8504704A1 (es) 1983-01-26 1984-01-24 Un compuesto de pirrol-2-acetilaminoacido
ES535101A Granted ES535101A0 (es) 1983-01-26 1984-08-10 Un procedimiento para la preparacion de nuevos derivados de pirrol-2-acetilaminoacido

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES529120A Expired ES8504704A1 (es) 1983-01-26 1984-01-24 Un compuesto de pirrol-2-acetilaminoacido

Country Status (12)

Country Link
EP (1) EP0115424B1 (es)
AU (1) AU556810B2 (es)
DE (1) DE3467164D1 (es)
DK (1) DK33284A (es)
ES (2) ES8504704A1 (es)
FI (1) FI840299A (es)
GB (1) GB2134111B (es)
HU (1) HU195232B (es)
IE (1) IE56608B1 (es)
NO (1) NO840292L (es)
NZ (1) NZ206818A (es)
YU (1) YU251283A (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1210673B (it) * 1982-02-26 1989-09-20 Medosan Ind Biochimi Antinfiammatoria amidi pirrolacetiche ad attivita'
IT1197688B (it) * 1983-07-29 1988-12-06 Medosan Ind Biochimi Attivita' antiflogistica,analgesica,antipiretica ed antiaggregante piastrinica di 1-metil-5-metilbenzoilpirrol-2-acetamido acetanilidi
CN103254109B (zh) * 2013-05-31 2015-01-28 山西大学 一种苯甲酰基吡咯衍生物及其合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES356485A1 (es) * 1967-07-26 1970-01-16 Mcneilab Inc Un procedimiento para la preparacion de nuevos acidos 5- aroilpirrol-2-carboxilicos y derivados de acido carboxilico.
US3752826A (en) * 1970-01-26 1973-08-14 Mcneilab Inc Aroyl substituted pyrroles
IT1210673B (it) * 1982-02-26 1989-09-20 Medosan Ind Biochimi Antinfiammatoria amidi pirrolacetiche ad attivita'

Also Published As

Publication number Publication date
GB2134111A (en) 1984-08-08
HU195232B (en) 1988-04-28
AU2378784A (en) 1984-08-02
GB2134111B (en) 1986-05-29
NZ206818A (en) 1986-03-14
DK33284A (da) 1984-07-27
DE3467164D1 (de) 1987-12-10
IE840167L (en) 1984-07-26
ES535101A0 (es) 1985-07-16
EP0115424A1 (en) 1984-08-08
EP0115424B1 (en) 1987-11-04
FI840299A (fi) 1984-07-27
ES529120A0 (es) 1985-05-01
AU556810B2 (en) 1986-11-20
DK33284D0 (da) 1984-01-25
GB8401876D0 (en) 1984-02-29
IE56608B1 (en) 1991-10-09
NO840292L (no) 1984-07-27
ES8504704A1 (es) 1985-05-01
YU251283A (en) 1986-04-30
FI840299A0 (fi) 1984-01-25

Similar Documents

Publication Publication Date Title
DE3272792D1 (en) Process for the preparation of 2-penem compounds
ES8506677A1 (es) Un procedimiento para la preparacion de nuevos derivados de 8-cloro71,5-benzotiazepina.
ES8204739A1 (es) Un procedimiento para preparar compuestos de cefem
CA2041168A1 (en) Use of alkylcarboxylic acid dimethylamides as crystallization inhibitors
EP0124186A3 (en) Imidazole-ethanol esters
NZ233970A (en) N-heteroaryl-purin-6-amines and pharmaceutical compositions
ES8704153A1 (es) Un procedimiento para preparar derivados de pirimidina
FR2355822A1 (fr) Derives d'esters de l'acide indolacetique. utiles comme anti-inflammatoires et analgesiques
ES8506620A1 (es) Un procedimiento para la preparacion de nuevos derivados de pirrol-2-acetilaminoacido
SE9301732D0 (sv) New centrally acting 5-,6-,7-, and 8-substituted sulphone esters of n-monosubstituted 2-aminotetralins
NZ216110A (en) 4-(z)-6-((2,4,5-cis -2-alkyl-4-(2-hydroxyphenyl)-1,3- dioxan-5-yl) hexenoic acid derivatives and pharmaceutical compositions
ES2053868T3 (es) 3-aminosidnoniminas substituidas, procedimientos para su obtencion y su empleo.
ES550972A0 (es) Un procedimiento para preparar nuevos derivados de imidiazol.
ES8602789A1 (es) Procedimiento para preparar derivados de 14-hidroxiimino- eburnano racemicos y opticamente activos
ATE63310T1 (de) Herstellung von thienoimidazolderivaten.
FR2363560A1 (fr) Nouveau compose a action analgesique et compositions therapeutiques en contenant
ATE17851T1 (de) Imidazolylkarbonsaeure, deren derivate und herstellung.
GB1113802A (en) Improvements in or relating to substituted quinolines and the manufacture thereof
FR2400508A1 (fr) Derives de l'acide oxanilique, utiles notamment pour ameliorer et controler les symptomes associes a l'asthme, et procede de preparation
JPS56127378A (en) 2-alkoxyindolizine derivative and its preparation
ES8300709A1 (es) Un metodo para la preparacion de derivados de pirazolidinona
JPS5436257A (en) Substituted benzoic acid amide
ES8307812A1 (es) Un procedimiento para la preparacion de nuevos amidin derivados del acido clavulawilo.
JPS57165376A (en) Novel 2-benzothiazolinone derivative and its preparation
FR2430769A1 (fr) Nouvelle composition analgesique contenant de l'((indolyl-3)-2 ethyl)-4 piperidine