ES8504704A1 - Un compuesto de pirrol-2-acetilaminoacido - Google Patents

Un compuesto de pirrol-2-acetilaminoacido

Info

Publication number
ES8504704A1
ES8504704A1 ES529120A ES529120A ES8504704A1 ES 8504704 A1 ES8504704 A1 ES 8504704A1 ES 529120 A ES529120 A ES 529120A ES 529120 A ES529120 A ES 529120A ES 8504704 A1 ES8504704 A1 ES 8504704A1
Authority
ES
Spain
Prior art keywords
compounds
utility
pyrrole
inflammatory
acid derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES529120A
Other languages
English (en)
Other versions
ES529120A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceuticals Inc
Original Assignee
McNeilab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/461,055 external-priority patent/US4585784A/en
Application filed by McNeilab Inc filed Critical McNeilab Inc
Publication of ES529120A0 publication Critical patent/ES529120A0/es
Publication of ES8504704A1 publication Critical patent/ES8504704A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE PIRROL-2-ACETILAMINOACIDO Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE Y ES HIDROGENO O METILO, Q ES METILO O CLORO; R PUEDE SER VARIOS RADICALES; Y N VALE 1 O 2.CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), EN LAS QUE X, R Y R PUEDEN SER VARIOS RADICALES Y Q E Y SON LOS MISMOS QUE EN LA FORMULA (I), EN UN DISOLVENTE APROTICO A UNA TEMPERATURA ENTRE 0JC Y 100JC; SEGUIDA DE LA SAPONIFICACION CON UN HIDROXIDO ALCALINO A TEMPERATURAS ENTRE 25JC Y 100JC.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANALGESICA Y ANTIINFLAMATORIA.
ES529120A 1983-01-26 1984-01-24 Un compuesto de pirrol-2-acetilaminoacido Expired ES8504704A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46104783A 1983-01-26 1983-01-26
US06/461,055 US4585784A (en) 1983-01-26 1983-01-26 Pyrrole-2-acetylamino acid derivative compounds

Publications (2)

Publication Number Publication Date
ES529120A0 ES529120A0 (es) 1985-05-01
ES8504704A1 true ES8504704A1 (es) 1985-05-01

Family

ID=27039899

Family Applications (2)

Application Number Title Priority Date Filing Date
ES529120A Expired ES8504704A1 (es) 1983-01-26 1984-01-24 Un compuesto de pirrol-2-acetilaminoacido
ES535101A Granted ES535101A0 (es) 1983-01-26 1984-08-10 Un procedimiento para la preparacion de nuevos derivados de pirrol-2-acetilaminoacido

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES535101A Granted ES535101A0 (es) 1983-01-26 1984-08-10 Un procedimiento para la preparacion de nuevos derivados de pirrol-2-acetilaminoacido

Country Status (12)

Country Link
EP (1) EP0115424B1 (es)
AU (1) AU556810B2 (es)
DE (1) DE3467164D1 (es)
DK (1) DK33284A (es)
ES (2) ES8504704A1 (es)
FI (1) FI840299A (es)
GB (1) GB2134111B (es)
HU (1) HU195232B (es)
IE (1) IE56608B1 (es)
NO (1) NO840292L (es)
NZ (1) NZ206818A (es)
YU (1) YU251283A (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1210673B (it) * 1982-02-26 1989-09-20 Medosan Ind Biochimi Antinfiammatoria amidi pirrolacetiche ad attivita'
IT1197688B (it) * 1983-07-29 1988-12-06 Medosan Ind Biochimi Attivita' antiflogistica,analgesica,antipiretica ed antiaggregante piastrinica di 1-metil-5-metilbenzoilpirrol-2-acetamido acetanilidi
CN103254109B (zh) * 2013-05-31 2015-01-28 山西大学 一种苯甲酰基吡咯衍生物及其合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES356485A1 (es) * 1967-07-26 1970-01-16 Mcneilab Inc Un procedimiento para la preparacion de nuevos acidos 5- aroilpirrol-2-carboxilicos y derivados de acido carboxilico.
US3752826A (en) * 1970-01-26 1973-08-14 Mcneilab Inc Aroyl substituted pyrroles
IT1210673B (it) * 1982-02-26 1989-09-20 Medosan Ind Biochimi Antinfiammatoria amidi pirrolacetiche ad attivita'

Also Published As

Publication number Publication date
HU195232B (en) 1988-04-28
DK33284A (da) 1984-07-27
NZ206818A (en) 1986-03-14
EP0115424B1 (en) 1987-11-04
EP0115424A1 (en) 1984-08-08
DK33284D0 (da) 1984-01-25
GB2134111A (en) 1984-08-08
IE56608B1 (en) 1991-10-09
IE840167L (en) 1984-07-26
ES8506620A1 (es) 1985-07-16
ES529120A0 (es) 1985-05-01
FI840299A (fi) 1984-07-27
GB8401876D0 (en) 1984-02-29
FI840299A0 (fi) 1984-01-25
ES535101A0 (es) 1985-07-16
NO840292L (no) 1984-07-27
AU556810B2 (en) 1986-11-20
YU251283A (en) 1986-04-30
AU2378784A (en) 1984-08-02
DE3467164D1 (de) 1987-12-10
GB2134111B (en) 1986-05-29

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