ES557559A0 - Un procedimiento para la preparacion de derivados de acidos griseolicos. - Google Patents
Un procedimiento para la preparacion de derivados de acidos griseolicos.Info
- Publication number
- ES557559A0 ES557559A0 ES557559A ES557559A ES557559A0 ES 557559 A0 ES557559 A0 ES 557559A0 ES 557559 A ES557559 A ES 557559A ES 557559 A ES557559 A ES 557559A ES 557559 A0 ES557559 A0 ES 557559A0
- Authority
- ES
- Spain
- Prior art keywords
- griseolic acid
- acid derivatives
- procedure
- preparation
- griseolic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- IAPZXUKYTCQQFE-QZKDJMESSA-N (2r,3r,3as,5s)-2-(6-aminopurin-9-yl)-5-[carboxy(hydroxy)methyl]-3-hydroxy-3,3a-dihydro-2h-furo[3,2-b]furan-5-carboxylic acid Chemical class NC1=NC=NC2=C1N=CN2[C@H]1[C@H](O)[C@@H]2O[C@](C(O)=O)(C(O)C(O)=O)C=C2O1 IAPZXUKYTCQQFE-QZKDJMESSA-N 0.000 title abstract 4
- IAPZXUKYTCQQFE-UHFFFAOYSA-N Griseolic acid Natural products NC1=NC=NC2=C1N=CN2C1C(O)C2OC(C(O)=O)(C(O)C(O)=O)C=C2O1 IAPZXUKYTCQQFE-UHFFFAOYSA-N 0.000 abstract 2
- GFFGJBXGBJISGV-UHFFFAOYSA-N adenyl group Chemical group N1=CN=C2N=CNC2=C1N GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 abstract 2
- 150000003212 purines Chemical class 0.000 abstract 2
- 102000004861 Phosphoric Diester Hydrolases Human genes 0.000 abstract 1
- 108090001050 Phosphoric Diester Hydrolases Proteins 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 229940083251 peripheral vasodilators purine derivative Drugs 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
- C07H19/207—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids the phosphoric or polyphosphoric acids being esterified by a further hydroxylic compound, e.g. flavine adenine dinucleotide or nicotinamide-adenine dinucleotide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8213285 | 1985-04-19 | ||
| JP9198985 | 1985-04-27 | ||
| JP9198785 | 1985-04-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES557559A0 true ES557559A0 (es) | 1988-02-16 |
| ES8801665A1 ES8801665A1 (es) | 1988-02-16 |
Family
ID=27303820
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES554178A Expired ES8802054A1 (es) | 1985-04-19 | 1986-04-19 | Un procedimiento para la preparacion de derivados de acidos griseolicos. |
| ES557558A Expired ES8801664A1 (es) | 1985-04-19 | 1987-05-21 | Un procedimiento para la preparacion de derivados de acidos griseolicos. |
| ES557560A Expired ES8801666A1 (es) | 1985-04-19 | 1987-05-21 | Un procedimiento para la prepracion de derivados de acidos griseolicos. |
| ES557559A Expired ES8801665A1 (es) | 1985-04-19 | 1987-05-21 | Un procedimiento para la preparacion de derivados de acidos griseolicos. |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES554178A Expired ES8802054A1 (es) | 1985-04-19 | 1986-04-19 | Un procedimiento para la preparacion de derivados de acidos griseolicos. |
| ES557558A Expired ES8801664A1 (es) | 1985-04-19 | 1987-05-21 | Un procedimiento para la preparacion de derivados de acidos griseolicos. |
| ES557560A Expired ES8801666A1 (es) | 1985-04-19 | 1987-05-21 | Un procedimiento para la prepracion de derivados de acidos griseolicos. |
Country Status (11)
| Country | Link |
|---|---|
| US (5) | US5498819A (es) |
| EP (1) | EP0214708B1 (es) |
| KR (1) | KR930007385B1 (es) |
| AT (2) | ATE129501T1 (es) |
| CA (1) | CA1267409A (es) |
| DE (3) | DE3667470D1 (es) |
| DK (1) | DK167878B1 (es) |
| ES (4) | ES8802054A1 (es) |
| FI (1) | FI94133C (es) |
| HK (2) | HK1005739A1 (es) |
| NO (1) | NO169901C (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0319316A3 (en) * | 1987-12-02 | 1990-11-28 | Sankyo Company Limited | Griseolic acid monoesters, their preparation and use |
| US5091431A (en) * | 1988-02-08 | 1992-02-25 | Schering Corporation | Phosphodiesterase inhibitors |
| US4971972A (en) * | 1989-03-23 | 1990-11-20 | Schering Corporation | Phosphodiesterase inhibitors having an optionally substituted purine derivative portion and a benzo- or cyclopenta-furan portion |
| JPH04112889A (ja) * | 1990-09-04 | 1992-04-14 | Kyowa Hakko Kogyo Co Ltd | Ｋｓ―５０５誘導体 |
| US5866702A (en) * | 1996-08-02 | 1999-02-02 | Cv Therapeutics, Incorporation | Purine inhibitors of cyclin dependent kinase 2 |
| CA2238283C (en) * | 1997-05-30 | 2002-08-20 | Cell Pathways, Inc. | Method for identifying compounds for inhibition of neoplastic lesions, pharmaceutical compositions from such compounds and uses of such compounds and compositions for treating neoplastic lesions |
| US6558787B1 (en) * | 1999-12-27 | 2003-05-06 | Kodak Polychrome Graphics Llc | Relation to manufacture of masks and electronic parts |
| EP1312363A1 (en) * | 2001-09-28 | 2003-05-21 | Pfizer Products Inc. | Methods of treatment and kits comprising a growth hormone secretagogue |
| US7342884B2 (en) * | 2002-03-13 | 2008-03-11 | Harmonic, Inc. | Method and apparatus for one directional communications in bidirectional communications channel |
| US20040043014A1 (en) * | 2002-08-30 | 2004-03-04 | Hiroyoshi Moriyama | Platelet aggregation inhibitor and supplement food effective for inhibiting platelet aggregation |
| WO2005018563A2 (en) * | 2003-08-22 | 2005-03-03 | Pharmacia Corporation | Compositions of a cyclooxygenase-2 selective inhibitor and a phosphodiesterase inhibitor for the treatment of ischemic mediated central nervous system disorders or injury |
| GB0601951D0 (en) | 2006-01-31 | 2006-03-15 | Novartis Ag | Organic compounds |
| WO2011081915A2 (en) * | 2009-12-15 | 2011-07-07 | Cebix Inc. | Methods for treating erectile dysfunction in patients with insulin-dependent diabetes |
| CN105636967B (zh) | 2013-08-12 | 2018-09-28 | 沙特基础工业公司 | 用于烯烃聚合的催化剂体系 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4035370A (en) * | 1971-11-03 | 1977-07-12 | Richter Gedeon Vegyeszeti Gyar Rt. | Alkaloid esters |
| US4167565A (en) * | 1976-11-08 | 1979-09-11 | Abbott Laboratories | Adenosine-5'-carboxamides and method of use |
| JPS5668695A (en) * | 1979-11-10 | 1981-06-09 | Sankyo Co Ltd | Enzyme inhibitor griseolic acid and its preparation |
| US4803271A (en) * | 1982-02-01 | 1989-02-07 | Syntex (U.S.A.) Inc. | Process for preparing guanine derivatives |
| US4783532A (en) * | 1983-10-28 | 1988-11-08 | Sankyo Company Limited | Process for preparing griseolic acid derivatives |
| JPS6094992A (ja) * | 1983-10-28 | 1985-05-28 | Sankyo Co Ltd | グリゼオ−ル酸誘導体 |
| JPS60246396A (ja) * | 1984-05-22 | 1985-12-06 | Sankyo Co Ltd | 酵素阻害物質ジヒドロデスオキシグリゼオ−ル酸及びその塩類 |
| US4788190A (en) * | 1986-12-24 | 1988-11-29 | Schering Corporation | 2,4,4-tri- and 2,2,4,4-tetra substituted-1,3-dioxolane antifungal, antiallergy compounds |
| US5091431A (en) * | 1988-02-08 | 1992-02-25 | Schering Corporation | Phosphodiesterase inhibitors |
| US4966912A (en) * | 1989-09-29 | 1990-10-30 | Uniroyal Chemical Company, Inc. | Fungicidal 3-imino-1,4-oxathiins |
| JPH0559085A (ja) * | 1990-12-27 | 1993-03-09 | Nippon Kayaku Co Ltd | イミダゾール塩基を有するオキセタノシン誘導体 |
| JPH0639472B2 (ja) * | 1991-12-21 | 1994-05-25 | メルシャン株式会社 | アゾール誘導体 |
-
1986
- 1986-04-18 DK DK179586A patent/DK167878B1/da not_active IP Right Cessation
- 1986-04-18 NO NO861533A patent/NO169901C/no not_active IP Right Cessation
- 1986-04-18 FI FI861655A patent/FI94133C/fi not_active IP Right Cessation
- 1986-04-19 ES ES554178A patent/ES8802054A1/es not_active Expired
- 1986-04-19 KR KR1019860003049A patent/KR930007385B1/ko not_active IP Right Cessation
- 1986-04-21 CA CA000507140A patent/CA1267409A/en not_active Expired - Fee Related
- 1986-04-21 DE DE8686303000T patent/DE3667470D1/de not_active Expired - Fee Related
- 1986-04-21 DE DE3650297T patent/DE3650297T2/de not_active Expired - Fee Related
- 1986-04-21 AT AT88121487T patent/ATE129501T1/de not_active IP Right Cessation
- 1986-04-21 DE DE3650429T patent/DE3650429T2/de not_active Expired - Fee Related
- 1986-04-21 EP EP86303000A patent/EP0214708B1/en not_active Expired
- 1986-04-21 AT AT88121486T patent/ATE121097T1/de not_active IP Right Cessation
-
1987
- 1987-05-21 ES ES557558A patent/ES8801664A1/es not_active Expired
- 1987-05-21 ES ES557560A patent/ES8801666A1/es not_active Expired
- 1987-05-21 ES ES557559A patent/ES8801665A1/es not_active Expired
-
1993
- 1993-09-30 US US08/130,154 patent/US5498819A/en not_active Expired - Fee Related
-
1994
- 1994-10-06 US US08/319,413 patent/US5760042A/en not_active Expired - Fee Related
-
1995
- 1995-05-09 US US08/437,634 patent/US5556975A/en not_active Expired - Fee Related
- 1995-05-09 US US08/437,632 patent/US5532369A/en not_active Expired - Fee Related
- 1995-05-09 US US08/437,644 patent/US5616600A/en not_active Expired - Fee Related
-
1998
- 1998-06-03 HK HK98104840A patent/HK1005739A1/xx not_active IP Right Cessation
- 1998-06-03 HK HK98104838A patent/HK1005738A1/xx not_active IP Right Cessation
Also Published As
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