ES555932A0 - Procedimiento para preparar 2-bromo-<-ergocriptina y sus sales acidas complementarias - Google Patents

Procedimiento para preparar 2-bromo-<-ergocriptina y sus sales acidas complementarias

Info

Publication number
ES555932A0
ES555932A0 ES555932A ES555932A ES555932A0 ES 555932 A0 ES555932 A0 ES 555932A0 ES 555932 A ES555932 A ES 555932A ES 555932 A ES555932 A ES 555932A ES 555932 A0 ES555932 A0 ES 555932A0
Authority
ES
Spain
Prior art keywords
acidal
ergocriptine
bromine
complementary
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES555932A
Other languages
English (en)
Other versions
ES8707236A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of ES555932A0 publication Critical patent/ES555932A0/es
Publication of ES8707236A1 publication Critical patent/ES8707236A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/02Ergot alkaloids of the cyclic peptide type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ES555932A 1985-06-12 1986-06-11 Procedimiento para preparar 2-bromo-<-ergocriptina y sus sales acidas complementarias Expired ES8707236A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU852300A HU193317B (en) 1985-06-12 1985-06-12 Process for producing 2-bromo-alpha-ergochristin

Publications (2)

Publication Number Publication Date
ES555932A0 true ES555932A0 (es) 1987-07-16
ES8707236A1 ES8707236A1 (es) 1987-07-16

Family

ID=10958743

Family Applications (1)

Application Number Title Priority Date Filing Date
ES555932A Expired ES8707236A1 (es) 1985-06-12 1986-06-11 Procedimiento para preparar 2-bromo-<-ergocriptina y sus sales acidas complementarias

Country Status (13)

Country Link
US (1) US4697017A (es)
JP (1) JPS61286390A (es)
BE (1) BE904897A (es)
CA (1) CA1256103A (es)
CH (1) CH667092A5 (es)
CS (1) CS262670B2 (es)
DE (1) DE3619617A1 (es)
ES (1) ES8707236A1 (es)
FR (1) FR2583419B1 (es)
GB (1) GB2176479B (es)
HU (1) HU193317B (es)
IT (1) IT1191806B (es)
YU (1) YU100886A (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU196394B (en) * 1986-06-27 1988-11-28 Richter Gedeon Vegyeszet Process for preparing 2-halogenated ergoline derivatives
GB9218242D0 (en) * 1992-08-27 1992-10-14 Ici Plc Chemical process
ATE336999T1 (de) * 1995-06-07 2006-09-15 Pliva D D Verfahren zur inhibition einer neoplastischen krankheit in saeugetieren
CN103073387A (zh) * 2013-02-08 2013-05-01 天津师范大学 一种9,10-二溴蒽的制备方法
CN105646547B (zh) * 2014-12-03 2019-05-17 四川海思科制药有限公司 一种甲磺酸溴隐亭化合物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH507249A (de) * 1968-05-31 1971-05-15 Sandoz Ag Verfahren zur Herstellung von 2-Brom-a-ergokryptin
CH573431A5 (en) * 1972-06-13 1976-03-15 Sandoz Ag Dibromo-dihydro-lysergic acid prepn. - by bromination of 9,10-dihydro-lysergic acid in inert solvent, pref. glacial alcoholic or propionic acid
DE2330912C3 (de) * 1972-06-22 1979-01-11 Societa Farmaceutici Italia S.P.A., Mailand (Italien) Verfahren zur Herstellung von Bromergolinverbindungen
DE2656344A1 (de) * 1975-12-23 1977-07-07 Sandoz Ag Ergolinderivate, ihre verwendung und herstellung
YU216177A (en) * 1977-09-09 1984-02-29 Rudolf Rucman Process for preparing 2-bromo ergosine
US4609731A (en) * 1979-10-10 1986-09-02 Sandoz Ltd. Process for brominating ergot alkaloids
DE3101535A1 (de) * 1981-01-14 1982-08-12 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue (2-halogen-ergolinyl)-n'.n'-diethyl-harnstoffderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
CH649300A5 (de) * 1981-08-07 1985-05-15 Sandoz Ag Ergopeptinderivate, ihre herstellung und verwendung.
DE3340025C2 (de) * 1983-11-03 1986-01-09 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur Herstellung von 2-Brom-8-ergolinyl-Verbindungen

Also Published As

Publication number Publication date
CS435886A2 (en) 1988-08-16
HU193317B (en) 1987-09-28
IT8620761A1 (it) 1987-12-11
CA1256103A (en) 1989-06-20
CS262670B2 (en) 1989-03-14
IT1191806B (it) 1988-03-23
CH667092A5 (de) 1988-09-15
BE904897A (fr) 1986-12-10
DE3619617A1 (de) 1986-12-18
FR2583419A1 (fr) 1986-12-19
HUT40445A (en) 1986-12-28
GB8614342D0 (en) 1986-07-16
JPS61286390A (ja) 1986-12-16
YU100886A (en) 1988-04-30
US4697017A (en) 1987-09-29
IT8620761A0 (it) 1986-06-11
GB2176479A (en) 1986-12-31
FR2583419B1 (fr) 1990-01-12
ES8707236A1 (es) 1987-07-16
GB2176479B (en) 1988-12-14

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960506