IT8620761A1 - PROCEDIMENTO PER LA PREPARAZIONE DI 2-BROMO-α -ERGOCRIPTINA - Google Patents
PROCEDIMENTO PER LA PREPARAZIONE DI 2-BROMO-α -ERGOCRIPTINAInfo
- Publication number
- IT8620761A1 IT8620761A1 IT1986A20761A IT2076186A IT8620761A1 IT 8620761 A1 IT8620761 A1 IT 8620761A1 IT 1986A20761 A IT1986A20761 A IT 1986A20761A IT 2076186 A IT2076186 A IT 2076186A IT 8620761 A1 IT8620761 A1 IT 8620761A1
- Authority
- IT
- Italy
- Prior art keywords
- ergocryptine
- bromo
- procedure
- preparation
- Prior art date
Links
- OZVBMTJYIDMWIL-AYFBDAFISA-N bromocriptine Chemical compound C1=CC(C=2[C@H](N(C)C[C@@H](C=2)C(=O)N[C@]2(C(=O)N3[C@H](C(N4CCC[C@H]4[C@]3(O)O2)=O)CC(C)C)C(C)C)C2)=C3C2=C(Br)NC3=C1 OZVBMTJYIDMWIL-AYFBDAFISA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/02—Ergot alkaloids of the cyclic peptide type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU852300A HU193317B (en) | 1985-06-12 | 1985-06-12 | Process for producing 2-bromo-alpha-ergochristin |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IT8620761A0 IT8620761A0 (it) | 1986-06-11 |
| IT8620761A1 true IT8620761A1 (it) | 1987-12-11 |
| IT1191806B IT1191806B (it) | 1988-03-23 |
Family
ID=10958743
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT20761/86A IT1191806B (it) | 1985-06-12 | 1986-06-11 | Procedimento per la preparazione di 2-bromo-alfa-ergocriptina |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4697017A (it) |
| JP (1) | JPS61286390A (it) |
| BE (1) | BE904897A (it) |
| CA (1) | CA1256103A (it) |
| CH (1) | CH667092A5 (it) |
| CS (1) | CS262670B2 (it) |
| DE (1) | DE3619617A1 (it) |
| ES (1) | ES8707236A1 (it) |
| FR (1) | FR2583419B1 (it) |
| GB (1) | GB2176479B (it) |
| HU (1) | HU193317B (it) |
| IT (1) | IT1191806B (it) |
| YU (1) | YU100886A (it) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU196394B (en) * | 1986-06-27 | 1988-11-28 | Richter Gedeon Vegyeszet | Process for preparing 2-halogenated ergoline derivatives |
| GB9218242D0 (en) * | 1992-08-27 | 1992-10-14 | Ici Plc | Chemical process |
| ATE336999T1 (de) * | 1995-06-07 | 2006-09-15 | Pliva D D | Verfahren zur inhibition einer neoplastischen krankheit in saeugetieren |
| CN103073387A (zh) * | 2013-02-08 | 2013-05-01 | 天津师范大学 | 一种9，10-二溴蒽的制备方法 |
| CN105646547B (zh) * | 2014-12-03 | 2019-05-17 | 四川海思科制药有限公司 | 一种甲磺酸溴隐亭化合物 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH507249A (de) * | 1968-05-31 | 1971-05-15 | Sandoz Ag | Verfahren zur Herstellung von 2-Brom-a-ergokryptin |
| CH573431A5 (en) * | 1972-06-13 | 1976-03-15 | Sandoz Ag | Dibromo-dihydro-lysergic acid prepn. - by bromination of 9,10-dihydro-lysergic acid in inert solvent, pref. glacial alcoholic or propionic acid |
| DE2330912C3 (de) * | 1972-06-22 | 1979-01-11 | Societa Farmaceutici Italia S.P.A., Mailand (Italien) | Verfahren zur Herstellung von Bromergolinverbindungen |
| DE2656344A1 (de) * | 1975-12-23 | 1977-07-07 | Sandoz Ag | Ergolinderivate, ihre verwendung und herstellung |
| YU216177A (en) * | 1977-09-09 | 1984-02-29 | Rudolf Rucman | Process for preparing 2-bromo ergosine |
| US4609731A (en) * | 1979-10-10 | 1986-09-02 | Sandoz Ltd. | Process for brominating ergot alkaloids |
| DE3101535A1 (de) * | 1981-01-14 | 1982-08-12 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue (2-halogen-ergolinyl)-n'.n'-diethyl-harnstoffderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel |
| CH649300A5 (de) * | 1981-08-07 | 1985-05-15 | Sandoz Ag | Ergopeptinderivate, ihre herstellung und verwendung. |
| DE3340025C2 (de) * | 1983-11-03 | 1986-01-09 | Schering AG, 1000 Berlin und 4709 Bergkamen | Verfahren zur Herstellung von 2-Brom-8-ergolinyl-Verbindungen |
-
1985
- 1985-06-12 HU HU852300A patent/HU193317B/hu not_active IP Right Cessation
-
1986
- 1986-05-30 US US06/869,203 patent/US4697017A/en not_active Expired - Fee Related
- 1986-06-10 BE BE0/216763A patent/BE904897A/fr not_active IP Right Cessation
- 1986-06-11 ES ES555932A patent/ES8707236A1/es not_active Expired
- 1986-06-11 YU YU01008/86A patent/YU100886A/xx unknown
- 1986-06-11 CH CH2364/86A patent/CH667092A5/de not_active IP Right Cessation
- 1986-06-11 IT IT20761/86A patent/IT1191806B/it active
- 1986-06-11 CA CA000511286A patent/CA1256103A/en not_active Expired
- 1986-06-11 JP JP61133952A patent/JPS61286390A/ja active Pending
- 1986-06-11 DE DE19863619617 patent/DE3619617A1/de not_active Withdrawn
- 1986-06-12 CS CS864358A patent/CS262670B2/cs unknown
- 1986-06-12 GB GB08614342A patent/GB2176479B/en not_active Expired
- 1986-06-12 FR FR868608487A patent/FR2583419B1/fr not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA1256103A (en) | 1989-06-20 |
| US4697017A (en) | 1987-09-29 |
| HUT40445A (en) | 1986-12-28 |
| CH667092A5 (de) | 1988-09-15 |
| GB8614342D0 (en) | 1986-07-16 |
| CS262670B2 (en) | 1989-03-14 |
| IT1191806B (it) | 1988-03-23 |
| JPS61286390A (ja) | 1986-12-16 |
| CS435886A2 (en) | 1988-08-16 |
| BE904897A (fr) | 1986-12-10 |
| ES555932A0 (es) | 1987-07-16 |
| ES8707236A1 (es) | 1987-07-16 |
| GB2176479A (en) | 1986-12-31 |
| DE3619617A1 (de) | 1986-12-18 |
| HU193317B (en) | 1987-09-28 |
| IT8620761A0 (it) | 1986-06-11 |
| YU100886A (en) | 1988-04-30 |
| FR2583419B1 (fr) | 1990-01-12 |
| GB2176479B (en) | 1988-12-14 |
| FR2583419A1 (fr) | 1986-12-19 |
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