ES543214A0 - Un procedimiento para preparar derivados de la guanina - Google Patents

Un procedimiento para preparar derivados de la guanina

Info

Publication number
ES543214A0
ES543214A0 ES543214A ES543214A ES543214A0 ES 543214 A0 ES543214 A0 ES 543214A0 ES 543214 A ES543214 A ES 543214A ES 543214 A ES543214 A ES 543214A ES 543214 A0 ES543214 A0 ES 543214A0
Authority
ES
Spain
Prior art keywords
prepare
procedure
guanine derivatives
guanine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES543214A
Other languages
English (en)
Other versions
ES8603888A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838322199A external-priority patent/GB8322199D0/en
Priority claimed from GB838325271A external-priority patent/GB8325271D0/en
Priority claimed from GB848408322A external-priority patent/GB8408322D0/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES8603888A1 publication Critical patent/ES8603888A1/es
Publication of ES543214A0 publication Critical patent/ES543214A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/18—Polyhydroxylic acyclic alcohols
    • C07C31/22—Trihydroxylic alcohols, e.g. glycerol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
    • C07C43/1782—Unsaturated ethers containing hydroxy or O-metal groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/007—Esters of unsaturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
ES543214A 1983-08-18 1985-05-16 Un procedimiento para preparar derivados de la guanina Granted ES543214A0 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB838322199A GB8322199D0 (en) 1983-08-18 1983-08-18 Pharmaceutical composition
GB838325271A GB8325271D0 (en) 1983-09-21 1983-09-21 Compounds
GB848408322A GB8408322D0 (en) 1984-03-30 1984-03-30 Compounds

Publications (2)

Publication Number Publication Date
ES8603888A1 ES8603888A1 (es) 1986-01-01
ES543214A0 true ES543214A0 (es) 1986-01-01

Family

ID=27262187

Family Applications (3)

Application Number Title Priority Date Filing Date
ES535283A Granted ES535283A0 (es) 1983-08-18 1984-08-17 Un procedimiento para la fabricacion de derivados de la guanina.
ES543214A Granted ES543214A0 (es) 1983-08-18 1985-05-16 Un procedimiento para preparar derivados de la guanina
ES543213A Expired ES8603887A1 (es) 1983-08-18 1985-05-16 Un procedimiento para preparar derivados de la guanina

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES535283A Granted ES535283A0 (es) 1983-08-18 1984-08-17 Un procedimiento para la fabricacion de derivados de la guanina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES543213A Expired ES8603887A1 (es) 1983-08-18 1985-05-16 Un procedimiento para preparar derivados de la guanina

Country Status (14)

Country Link
US (3) US5075445A (es)
EP (1) EP0141927B1 (es)
JP (2) JP2519882B2 (es)
BG (1) BG61325B2 (es)
CA (1) CA1339818C (es)
CY (1) CY1746A (es)
CZ (1) CZ283182B6 (es)
DE (1) DE3485225D1 (es)
ES (3) ES535283A0 (es)
GR (1) GR80121B (es)
HK (1) HK126093A (es)
IE (1) IE58334B1 (es)
MX (1) MX160431A (es)
NZ (1) NZ209248A (es)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0141927B1 (en) * 1983-08-18 1991-10-30 Beecham Group Plc Antiviral guanine derivatives
US5684153A (en) 1984-08-16 1997-11-04 Beecham Group Plc Process for the preparation of purine derivatives
IL73682A (en) * 1983-12-20 1991-08-16 Medivir Ab Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation
DE3571810D1 (en) * 1984-01-26 1989-08-31 Merck & Co Inc Substituted butyl guanines and their utilization in antiviral compositions
EP0182024B1 (en) * 1984-09-20 1991-04-03 Beecham Group Plc Purine derivatives and their pharmaceutical use
GB8507606D0 (en) 1985-03-23 1985-05-01 Beecham Group Plc Process
DE3671227D1 (de) * 1985-07-27 1990-06-21 Beecham Group Plc 9-substituierte guaninmonohydrate.
GB8628826D0 (en) * 1986-12-02 1987-01-07 Beecham Group Plc Pharmaceutical products
US5175288A (en) * 1987-08-01 1992-12-29 Beecham Group P.L.C. Process for preparing purine derivatives and intermediates thereof
ES2098219T3 (es) * 1987-08-01 1997-05-01 Beecham Group Plc Compuestos de purina y su preparacion.
US5284837A (en) * 1988-05-06 1994-02-08 Medivir Ab Derivatives of purine, process for their preparation and a pharmaceutical preparation
GB8817607D0 (en) * 1988-07-23 1988-09-01 Beecham Group Plc Novel process
US4966895A (en) * 1989-02-02 1990-10-30 Merck & Co. Inc. Cyclic monophosphates of purine and pyrimidine acyclonucleosides as anti-retroviral agents
CA2009109A1 (en) * 1989-02-02 1990-08-02 John Hannah Antiviral acyclonucleosides and acyclonucleotides
GB8904855D0 (en) * 1989-03-03 1989-04-12 Beecham Group Plc Pharmaceutical treatment
GB8917959D0 (en) * 1989-08-05 1989-09-20 Beecham Group Plc Pharmaceutical formulation
GB9001886D0 (en) * 1990-01-26 1990-03-28 Beecham Group Plc Pharmaceutical formulation
US6469015B1 (en) 1990-01-26 2002-10-22 Novartis International Pharmaceutical Ltd Pharmaceutical formulation
GB9004647D0 (en) * 1990-03-01 1990-04-25 Beecham Group Plc Pharmaceuticals
GB9015051D0 (en) * 1990-07-07 1990-08-29 Beecham Group Plc Pharmaceutical treatment
US5674869A (en) * 1990-07-07 1997-10-07 Beecham Group Plc Pharmaceutical treatment
GB9102127D0 (en) * 1991-01-31 1991-03-13 Smithkline Beecham Plc Pharmaceuticals
CA2076886C (en) * 1991-11-22 2002-06-11 Masami Igi Method for production of 2-amino-6-halogenopurine and synthesis intermediate therefor
GB9201961D0 (en) 1992-01-30 1992-03-18 Smithkline Beecham Plc Pharmaceuticals
IL111138A (en) * 1993-10-05 1997-04-15 Smithkline Beecham Plc Pharmaceutical compositions comprising penciclovir and/or its bioprecursor and/or its derivatives for the treatment and prophylaxis of post-herpetic neuralgia
US6124304A (en) * 1993-10-05 2000-09-26 Smithkline Beecham Plc Penciclovir for the treatment of zoster associated pain
GB9326177D0 (en) * 1993-12-22 1994-02-23 Smithkline Beecham Plc Pharmaceuticals
US6683084B1 (en) 1993-11-12 2004-01-27 Novartis International Pharmaceutical Ltd. Use of 2-amino purine derivatives for the treatment and prophylaxis of human herpes virus 6 infections
GB9323404D0 (en) * 1993-11-12 1994-01-05 Smithkline Beecham Plc Pharmaceuticals
GB9323403D0 (en) * 1993-11-12 1994-01-05 Smithkline Beecham Plc Pharmaceuticals
GB9402161D0 (en) * 1994-02-04 1994-03-30 Wellcome Found Chloropyrimidine intermediates
GB9407698D0 (en) * 1994-04-19 1994-06-15 Smithkline Beecham Plc Pharmaceuticals
US5525606A (en) 1994-08-01 1996-06-11 The United States Of America As Represented By The Department Of Health And Human Services Substituted 06-benzylguanines and 6(4)-benzyloxypyrimidines
US5840763A (en) * 1994-12-12 1998-11-24 Smithkline Beecham Plc Treatment of a latent infection of herpes viruses
KR100382707B1 (ko) * 1994-12-12 2003-08-19 노파르티스 인터내셔널 파마슈티칼 리미티드 잠재적허피스바이러스감염의치료및예방을위한아미노퓨린항바이러스제의용도
US5559114A (en) * 1994-12-16 1996-09-24 Exley; Ray W. Treatment of autoimmune disease using 2-amino purine derivatives
GB9504497D0 (en) * 1995-03-07 1995-04-26 Smithkline Beecham Plc Pharmaceuticals
CA2249598A1 (en) * 1996-03-26 1997-10-02 Paul Joseph Gilligan Aryloxy- and arylthio-fused pyridines and pyrimidines and derivatives
GB9615253D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
GB9615276D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
GB9615275D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
AT412211B (de) * 1996-07-20 2004-11-25 Novartis Int Pharm Ltd Verfahren zur herstellung von penciclovir und famciclovir
KR19980028023A (ko) * 1996-10-19 1998-07-15 김준웅 Ο-아실-ο-아미노산 9-(4-하이드록시-3-하이드록시메틸부트-1-일구아닌 에스테르 유도체
US6060458A (en) * 1998-02-13 2000-05-09 The United States Of America As Represented By The Department Of Health And Human Services Oligodeoxyribonucleotides comprising O6 -benzylguanine and their use
GB9807116D0 (en) 1998-04-02 1998-06-03 Smithkline Beecham Plc Novel process
ATE287268T1 (de) 1998-11-02 2005-02-15 Gilead Sciences Inc Kombinationstherapie zur behandlung von hepatitis b infektionen
US6407077B1 (en) 1998-11-05 2002-06-18 Emory University β-L nucleosides for the treatment of HIV infection
US6107303A (en) * 1999-03-15 2000-08-22 Demarco; Charlene C. Treatment of Epstein Barr infection
AUPQ806700A0 (en) * 2000-06-08 2000-07-06 Commonwealth Scientific And Industrial Research Organisation Antiviral agents
CA2690137C (en) 2001-03-01 2012-11-13 Gilead Sciences, Inc. Polymorphic and other crystalline forms of cis-ftc
ITMI20021533A1 (it) * 2002-07-12 2004-01-12 Recordati Chem Pharm Processo per la preparazione di 2-acetossimetil-4-alo-but-1-il acetati
ATE398455T1 (de) * 2003-01-14 2008-07-15 Gilead Sciences Inc Zusammensetzungen und verfahren zur antiviralen kombinationstherapie
MX2007006387A (es) * 2004-12-03 2007-06-20 Hoffmann La Roche Derivados de piridina 3-substituidos como antagonistas h3.
BRPI0517032A (pt) * 2004-12-16 2008-09-30 Hoffmann La Roche compostos, processo para a sua manufatura, composições farmacêuticas que os compreendem, método para o tratamento e/ou prevenção de enfermidades e utilização desses compostos
AU2006230269A1 (en) 2005-03-30 2006-10-05 Novartis Ag Penciclovir or famciclovir for the treatment of recurrent genital herpes with a one-day application
GB2426247A (en) * 2005-05-20 2006-11-22 Arrow Int Ltd Methods of preparing purine derivatives such as famciclovir
TWI375560B (en) * 2005-06-13 2012-11-01 Gilead Sciences Inc Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
EP2170840A1 (en) * 2007-06-21 2010-04-07 Aurobindo Pharma Ltd An improved process for preparing purine derivative
WO2009067630A1 (en) 2007-11-21 2009-05-28 Exley Ray W 2-amino purine derivatives and their use as anti-herpetic agents
WO2009120358A1 (en) * 2008-03-27 2009-10-01 Nektar Therapeutics Oligomer-nitrogenous base conjugates
WO2009129385A1 (en) * 2008-04-16 2009-10-22 Abbott Laboratories Cationic lipids and uses thereof
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
WO2010075517A2 (en) * 2008-12-23 2010-07-01 Pharmasset, Inc. Nucleoside analogs
CL2009002207A1 (es) 2008-12-23 2011-02-18 Gilead Pharmasset Llc Compuestos derivados de 3-hidroxi-5-(9h-purin-9-il)tetrahidrofuran-2-il, inhibidor de la replicacion de arn viral dependiente de arn; composicion farmaceutica; uso para el tratamiento de hepatitis c.
SG172363A1 (en) 2008-12-23 2011-07-28 Pharmasset Inc Synthesis of purine nucleosides
WO2011035120A2 (en) * 2009-09-17 2011-03-24 Gk Ventures, L.L.C. Therapeutic composition to treat lesions caused by herpes simplex virus
AP3515A (en) 2010-03-31 2016-01-11 Gilead Pharmasset Llc Nucleoside phosphoramidates
AU2013257951A1 (en) 2012-05-11 2015-01-22 Akron Molecules Ag Use of compounds for the treatment of pain
US9474400B2 (en) 2012-07-27 2016-10-25 Anthony C. Farris Combination bracket and garment hanger system and assembly mountable to an overhead trim piece associated with a doorway such as for rotatably supporting a garment during steam cleaning
US10342372B2 (en) 2012-07-27 2019-07-09 Anthony C. Farris Combination bracket and garment hanger system and assembly mountable to an overhead trim piece associated with a doorway such as for rotatably supporting a garment during steam cleaning
US9227990B2 (en) 2012-10-29 2016-01-05 Cipla Limited Antiviral phosphonate analogues and process for preparation thereof
CN104086552B (zh) * 2014-07-31 2016-01-13 济南兆康医药科技有限公司 一种喷昔洛韦的精制方法
SI3504210T1 (sl) * 2016-08-29 2021-08-31 F. Hoffmann-La Roche Ag 7-substituirane sulfonimidoilpurinonske spojine za zdravljenje virusne okužbe in zaščito pred njo
CN108314685B (zh) * 2018-03-16 2020-08-25 上药康丽（常州）药业有限公司 一种2-氨基-6-氯-9-(4-乙酰氧基-3-乙酰氧甲基丁基)嘌呤的制备方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3624251A (en) * 1970-01-16 1971-11-30 Diagnostic Data Inc Orgotein purification process by heating above 65{20 {0 c.
US3706181A (en) * 1970-11-20 1972-12-19 Tenneco Chem Process for the safe handling of c{11 {11 and c{11 {11 acetylenic hydrocarbons
US3688438A (en) * 1970-12-28 1972-09-05 Texaco Development Corp Production of a methane-rich synthesis gas
US3790365A (en) * 1971-06-21 1974-02-05 Ethyl Corp Method of making metal foams by sequential expansion
US4146715A (en) * 1975-08-27 1979-03-27 Burroughs Wellcome Co. 2-amido-9-(2-acyloxyethoxymethyl)hypoxanthines
IL64501A (en) * 1980-12-22 1985-07-31 Astra Laekemedel Ab 9-substituted 4-hydroxybutyl guanine derivatives,their preparation and antiviral use
US4507305A (en) * 1981-05-21 1985-03-26 Syntex (U.S.A.) Inc. 9-(1,3-Dihydroxy-2-propoxymethyl)guanine as antiviral agent
ES8403128A1 (es) * 1981-08-11 1983-10-01 Wellcome Found "un procedimiento para preparar derivados de purina".
US4451478A (en) * 1982-03-12 1984-05-29 Newport Pharmaceuticals International, Inc. Imidazole compounds
US4461757A (en) * 1983-02-23 1984-07-24 Ens Bio Logicals Inc. Dimethylaminomethylenated anti-herpes compounds
EP0141927B1 (en) * 1983-08-18 1991-10-30 Beecham Group Plc Antiviral guanine derivatives
IL73682A (en) * 1983-12-20 1991-08-16 Medivir Ab Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation
US4565867A (en) * 1984-01-05 1986-01-21 Melamine Chemicals, Inc. Anhydrous high-pressure melamine synthesis
US4845084A (en) * 1984-01-26 1989-07-04 Merck & Co., Inc. Phosphate derivatives of substituted butyl guanines, antiviral compositions containing them, and methods of treating viral infections with them
DE3571810D1 (en) * 1984-01-26 1989-08-31 Merck & Co Inc Substituted butyl guanines and their utilization in antiviral compositions
US4689129A (en) * 1985-07-16 1987-08-25 The Dow Chemical Company Process for the preparation of submicron-sized titanium diboride
DE3671227D1 (de) * 1985-07-27 1990-06-21 Beecham Group Plc 9-substituierte guaninmonohydrate.
US4714787A (en) * 1985-09-03 1987-12-22 Mobil Oil Corporation Production of ethers from linear olefins
US4910035A (en) * 1989-03-08 1990-03-20 Consolidated Flavor Corporation Process and product for making flavored milk
US5401861A (en) * 1992-06-22 1995-03-28 Eli Lilly And Company Low temperature process for preparing alpha-anomer enriched 2-deoxy-2,2-difluoro-D-ribofuranosyl sulfonates
US5185365A (en) * 1992-06-24 1993-02-09 Cornell Research Foundation, Inc. Insect deterrent azamcrolides
US5670668A (en) * 1996-07-03 1997-09-23 Eastman Chemical Company Crystalline tocotrienol esters

Also Published As

Publication number Publication date
CZ283182B6 (cs) 1998-01-14
JPS6058982A (ja) 1985-04-05
NZ209248A (en) 1988-01-08
BG61325B2 (bg) 1997-05-30
IE842123L (en) 1985-02-18
CA1339818C (en) 1998-04-14
JP2519882B2 (ja) 1996-07-31
ES8603888A1 (es) 1986-01-01
IE58334B1 (en) 1993-09-08
ES543213A0 (es) 1986-01-01
EP0141927A2 (en) 1985-05-22
EP0141927B1 (en) 1991-10-30
GR80121B (en) 1984-12-17
MX160431A (es) 1990-02-22
JPH06293764A (ja) 1994-10-21
JP2543822B2 (ja) 1996-10-16
CY1746A (en) 1994-06-03
ES8602791A1 (es) 1985-12-01
ES8603887A1 (es) 1986-01-01
DE3485225D1 (de) 1991-12-05
EP0141927A3 (en) 1986-03-12
CZ391491A3 (en) 1993-01-13
US6579981B1 (en) 2003-06-17
HK126093A (en) 1993-11-19
ES535283A0 (es) 1985-12-01
US6573378B1 (en) 2003-06-03
US5075445A (en) 1991-12-24

Similar Documents

Publication Publication Date Title
ES543213A0 (es) Un procedimiento para preparar derivados de la guanina
ES540812A0 (es) Un procedimiento para la preparacion de nuevos derivados delaminometil-oxooxazolidinil-benceno
ES537440A0 (es) Un procedimiento para preparar 1-amino-4-nitro-acridinonas sustituidas
ES548671A0 (es) Un procedimiento para la preparacion de un derivado de dihi-dropiridina
ES539883A0 (es) Procedimiento para preparar nuevas 1-bencil-aminoalquil-pi- rrolidinonas
ES539136A0 (es) Un procedimiento para la preparacion de derivados de glicerina
ES541229A0 (es) Un procedimiento para la preparacion de nuevos derivados delcromano
ES540003A0 (es) Un procedimiento para preparar un derivado de octahidrobenzo(f) quinoleina
ES543646A0 (es) Un procedimiento para la preparacion de derivados esteroida-les
ES550241A0 (es) Procedimiento para preparar nuevos derivados imidazo
ES533842A0 (es) Un procedimiento para la obtencion de derivados de amino-pirimidina
ES529462A0 (es) Un procedimiento para la preparacion de nuevos derivados de benzotiazina
ES550240A0 (es) Procedimiento para preparar nuevos derivados imidazo
ES537650A0 (es) Un procedimiento para preparar nuevos derivados de milbemicinas.
AR240816A1 (es) Procedimiento para producir nuevos derivados de la cumarina
ES533673A0 (es) Procedimiento para la obtencion de un derivado de fenilsulfonilguanidina
ES532172A0 (es) Un procedimiento para la preparacion de derivados de pirimidona
ES544117A0 (es) Procedimiento para preparar nuevos bencimidazoles
ES549804A0 (es) Procedimiento para preparar nuevos derivados imidazo
ES547599A0 (es) Un procedimiento para preparar nuevos derivados de ciano-2- bencimidazol
ES535392A0 (es) Un procedimiento para la preparacion de derivados de imidazobenzodiacepina
ES546645A0 (es) Procedimiento para preparar un pseudooligosacarido
ES545777A0 (es) Un procedimiento para la preparacion de nuevos derivados de feniletanamina
ES557313A0 (es) Procedimiento para preparar derivados de fenilpirazina
ES531498A0 (es) Un procedimiento para la preparacion de derivados de pirimidinatriona

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20051003