ES535283A0 - Un procedimiento para la fabricacion de derivados de la guanina. - Google Patents

Un procedimiento para la fabricacion de derivados de la guanina.

Info

Publication number
ES535283A0
ES535283A0 ES535283A ES535283A ES535283A0 ES 535283 A0 ES535283 A0 ES 535283A0 ES 535283 A ES535283 A ES 535283A ES 535283 A ES535283 A ES 535283A ES 535283 A0 ES535283 A0 ES 535283A0
Authority
ES
Spain
Prior art keywords
procedure
manufacture
guanine derivatives
guanine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES535283A
Other languages
English (en)
Other versions
ES8602791A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838322199A external-priority patent/GB8322199D0/en
Priority claimed from GB838325271A external-priority patent/GB8325271D0/en
Priority claimed from GB848408322A external-priority patent/GB8408322D0/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES8602791A1 publication Critical patent/ES8602791A1/es
Publication of ES535283A0 publication Critical patent/ES535283A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/18—Polyhydroxylic acyclic alcohols
    • C07C31/22—Trihydroxylic alcohols, e.g. glycerol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
    • C07C43/1782—Unsaturated ethers containing hydroxy or O-metal groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/007—Esters of unsaturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
ES535283A 1983-08-18 1984-08-17 Un procedimiento para la fabricacion de derivados de la guanina. Granted ES535283A0 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB838322199A GB8322199D0 (en) 1983-08-18 1983-08-18 Pharmaceutical composition
GB838325271A GB8325271D0 (en) 1983-09-21 1983-09-21 Compounds
GB848408322A GB8408322D0 (en) 1984-03-30 1984-03-30 Compounds

Publications (2)

Publication Number Publication Date
ES8602791A1 ES8602791A1 (es) 1985-12-01
ES535283A0 true ES535283A0 (es) 1985-12-01

Family

ID=27262187

Family Applications (3)

Application Number Title Priority Date Filing Date
ES535283A Granted ES535283A0 (es) 1983-08-18 1984-08-17 Un procedimiento para la fabricacion de derivados de la guanina.
ES543213A Expired ES8603887A1 (es) 1983-08-18 1985-05-16 Un procedimiento para preparar derivados de la guanina
ES543214A Expired ES8603888A1 (es) 1983-08-18 1985-05-16 Un procedimiento para preparar derivados de la guanina

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES543213A Expired ES8603887A1 (es) 1983-08-18 1985-05-16 Un procedimiento para preparar derivados de la guanina
ES543214A Expired ES8603888A1 (es) 1983-08-18 1985-05-16 Un procedimiento para preparar derivados de la guanina

Country Status (14)

Country Link
US (3) US5075445A (es)
EP (1) EP0141927B1 (es)
JP (2) JP2519882B2 (es)
BG (1) BG61325B2 (es)
CA (1) CA1339818C (es)
CY (1) CY1746A (es)
CZ (1) CZ283182B6 (es)
DE (1) DE3485225D1 (es)
ES (3) ES535283A0 (es)
GR (1) GR80121B (es)
HK (1) HK126093A (es)
IE (1) IE58334B1 (es)
MX (1) MX160431A (es)
NZ (1) NZ209248A (es)

Families Citing this family (75)

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US5684153A (en) 1984-08-16 1997-11-04 Beecham Group Plc Process for the preparation of purine derivatives
DE3485225D1 (de) * 1983-08-18 1991-12-05 Beecham Group Plc Antivirale guanin-derivate.
IL73682A (en) * 1983-12-20 1991-08-16 Medivir Ab Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation
EP0152316B1 (en) * 1984-01-26 1989-07-26 Merck & Co. Inc. Substituted butyl guanines and their utilization in antiviral compositions
EP0182024B1 (en) * 1984-09-20 1991-04-03 Beecham Group Plc Purine derivatives and their pharmaceutical use
GB8507606D0 (en) 1985-03-23 1985-05-01 Beecham Group Plc Process
DE3671227D1 (de) 1985-07-27 1990-06-21 Beecham Group Plc 9-substituierte guaninmonohydrate.
GB8628826D0 (en) * 1986-12-02 1987-01-07 Beecham Group Plc Pharmaceutical products
US5175288A (en) * 1987-08-01 1992-12-29 Beecham Group P.L.C. Process for preparing purine derivatives and intermediates thereof
EP0302644B1 (en) * 1987-08-01 1997-01-29 Beecham Group Plc Purine compounds and their preparation
US5284837A (en) * 1988-05-06 1994-02-08 Medivir Ab Derivatives of purine, process for their preparation and a pharmaceutical preparation
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CA2009109A1 (en) * 1989-02-02 1990-08-02 John Hannah Antiviral acyclonucleosides and acyclonucleotides
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CN104086552B (zh) * 2014-07-31 2016-01-13 济南兆康医药科技有限公司 一种喷昔洛韦的精制方法
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CN108314685B (zh) * 2018-03-16 2020-08-25 上药康丽（常州）药业有限公司 一种2-氨基-6-氯-9-(4-乙酰氧基-3-乙酰氧甲基丁基)嘌呤的制备方法

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Also Published As

Publication number Publication date
US6573378B1 (en) 2003-06-03
GR80121B (en) 1984-12-17
ES8602791A1 (es) 1985-12-01
JP2543822B2 (ja) 1996-10-16
ES543214A0 (es) 1986-01-01
CZ391491A3 (en) 1993-01-13
CA1339818C (en) 1998-04-14
JP2519882B2 (ja) 1996-07-31
BG61325B2 (bg) 1997-05-30
JPH06293764A (ja) 1994-10-21
NZ209248A (en) 1988-01-08
MX160431A (es) 1990-02-22
CY1746A (en) 1994-06-03
IE58334B1 (en) 1993-09-08
EP0141927A2 (en) 1985-05-22
EP0141927A3 (en) 1986-03-12
CZ283182B6 (cs) 1998-01-14
IE842123L (en) 1985-02-18
JPS6058982A (ja) 1985-04-05
HK126093A (en) 1993-11-19
ES543213A0 (es) 1986-01-01
ES8603888A1 (es) 1986-01-01
US6579981B1 (en) 2003-06-17
ES8603887A1 (es) 1986-01-01
US5075445A (en) 1991-12-24
DE3485225D1 (de) 1991-12-05
EP0141927B1 (en) 1991-10-30

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Legal Events

Date Code Title Description
PC1A Transfer granted
FD1A Patent lapsed

Effective date: 20050704