ES534098A0 - Procedimiento para la obtencion de eglinas b o c modificadas - Google Patents

Procedimiento para la obtencion de eglinas b o c modificadas

Info

Publication number
ES534098A0
ES534098A0 ES534098A ES534098A ES534098A0 ES 534098 A0 ES534098 A0 ES 534098A0 ES 534098 A ES534098 A ES 534098A ES 534098 A ES534098 A ES 534098A ES 534098 A0 ES534098 A0 ES 534098A0
Authority
ES
Spain
Prior art keywords
eglins
procedure
obtaining modified
compounds
modified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES534098A
Other languages
English (en)
Spanish (es)
Other versions
ES8601108A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES8601108A1 publication Critical patent/ES8601108A1/es
Publication of ES534098A0 publication Critical patent/ES534098A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Paper (AREA)
ES534098A 1983-07-07 1984-07-06 Procedimiento para la obtencion de eglinas b o c modificadas Granted ES534098A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3324534A DE3324534A1 (de) 1983-07-07 1983-07-07 Modifizierte protease-inhibitoren, verfahren zu ihrer herstellung und daraus bereitete pharmazeutische mittel

Publications (2)

Publication Number Publication Date
ES8601108A1 ES8601108A1 (es) 1985-10-16
ES534098A0 true ES534098A0 (es) 1985-10-16

Family

ID=6203414

Family Applications (1)

Application Number Title Priority Date Filing Date
ES534098A Granted ES534098A0 (es) 1983-07-07 1984-07-06 Procedimiento para la obtencion de eglinas b o c modificadas

Country Status (10)

Country Link
US (1) US4636489A (en, 2012)
EP (1) EP0134479B1 (en, 2012)
JP (1) JPH0670077B2 (en, 2012)
AT (1) ATE32728T1 (en, 2012)
CA (1) CA1230069A (en, 2012)
DE (2) DE3324534A1 (en, 2012)
DK (1) DK165988C (en, 2012)
ES (1) ES534098A0 (en, 2012)
GR (1) GR82243B (en, 2012)
IE (1) IE57698B1 (en, 2012)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6342373B1 (en) * 1983-11-21 2002-01-29 Ucp Gen-Pharma Ag Process for preparing recombinant eglin, protease inhibitor
DE3506992A1 (de) * 1985-02-27 1986-08-28 Plantorgan Werk Heinrich G.E. Christensen, KG, 2903 Bad Zwischenahn Modifizierte hirudine, verfahren zu deren herstellung und pharmazeutische mittel, die diese wirkstoffe enthalten
US5166134A (en) * 1986-12-24 1992-11-24 John Lezdey Treatment of allergic rhinitis
EP0332576B1 (de) * 1988-03-07 1994-04-06 Ciba-Geigy Ag Modifizierte Proteine
US5180667A (en) * 1988-03-07 1993-01-19 Ciba-Geigy Corporation Genes encoding eglin C mutants
US5114921A (en) * 1988-05-27 1992-05-19 The Children's Hospital Of Philadelphia Amphiphilic peptides and use thereof
ATE115146T1 (de) * 1988-05-27 1994-12-15 Philadelphia Children Hospital Amphiphile peptide und deren verwendung.
US5268296A (en) * 1988-06-11 1993-12-07 Ciba-Geigy Corporation DNA vector and recombinant host cell for production of hirullin P6 and P18
DE58907266T2 (de) * 1988-06-11 1994-09-29 Ciba Geigy Ag Polypeptide mit einer die Koagulierung hemmenden Wirkung.
US5254535A (en) * 1989-04-17 1993-10-19 The Children's Hospital Of Pennsylvania Composition and treatment with biologically active peptides and antibiotic
EP0514464A4 (en) * 1990-02-08 1993-04-28 Magainin Sciences, Inc. Biologically active amphiphilic peptides and method of inhibiting growth of target cells, virus or virally-infected cell
US5459237A (en) * 1990-02-08 1995-10-17 Magainin Pharmaceuticals Inc. Peptide compositions and uses therefor
US5792831A (en) * 1990-02-08 1998-08-11 Magainin Pharmaceuticals Inc. Analogues of magainin peptides containing D-amino acids
EP0533795A4 (en) * 1990-05-14 1993-10-20 Magainin Sciences, Inc. Composition of and treatment with biologically active peptides having d-amino acid residues
US5208220A (en) * 1990-06-27 1993-05-04 Magainin Pharmaceuticals, Inc. Composition and treatment with biologically active peptides and antibiotics which inhibit DNA gyrase
WO1992000090A1 (en) * 1990-06-27 1992-01-09 Magainin Pharmaceuticals Inc. Composition and treatment with biologically active peptides and antibiotics which inhibit dna gyrase
HU217612B (hu) * 1991-05-23 2000-03-28 Merrel Dow Pharmaceuticals Inc. Eljárás elasztáz és katepszin G inhibitor hatású peptidek előállítására
US5478811A (en) * 1991-08-22 1995-12-26 Merrell Dow Pharmaceuticals Inc. Orally-active elastase inhibitors
US5714470A (en) * 1991-08-22 1998-02-03 Merrell Pharmaceuticals, Inc. Orally-active elastase inhibitors
JPH07500342A (ja) * 1991-10-16 1995-01-12 ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィア 生物学的活性ペプチドおよび抗生物質を有する組成物およびこれを用いた治療
CA2191844C (en) * 1994-06-02 2001-07-24 Norton P. Peet Acylated enol derivatives as prodrugs of elastase inhibitors
FI964789A0 (fi) * 1994-06-02 1996-11-29 Merrell Pharma Inc Elastaasin pefluorialkyyliketoni-inhibiittoreita ja menetelmiä niiden valmistamiseksi
US5948886A (en) * 1996-11-20 1999-09-07 Hoechst Marion Roussel, Inc. Acylated enol derivatives of α-ketoesters and α-ketoamides
US6172044B1 (en) 1995-12-01 2001-01-09 Aventis Pharmaceuticals Inc. Acylated enol derivative of α-ketoesters and α-ketoamides
DK0929577T3 (da) 1996-09-24 2003-10-06 Procter & Gamble Stabiliserede proteinholdige protease-inhibitorer og varianter deraf
US7001884B2 (en) * 2001-06-18 2006-02-21 Regents Of The University Of Michigan Eglin c based drugs for treatment of disease
DE102005007313A1 (de) * 2005-02-17 2006-08-24 Wacker Chemie Ag Verfahren zur Herstellung von Entschäumerformulierungen
KR101237116B1 (ko) * 2010-11-12 2013-02-25 대한유화공업 주식회사 내충격성 및 내압특성이 우수한 폴리프로필렌 조성물
CN110551707A (zh) * 2019-10-17 2019-12-10 山西大学 一种纯化中性或碱性蛋白酶的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2808396C2 (de) * 1978-02-27 1984-04-19 Plantorgan Werk Heinrich G.E. Christensen, KG, 2903 Bad Zwischenahn Protease-Inhibitoren
US4250086A (en) * 1979-11-19 1981-02-10 Ortho Pharmaceutical Corporation Method and composition for preparation of H-SAR-LYS-SAR-GLN-NH2

Also Published As

Publication number Publication date
DE3469534D1 (en) 1988-04-07
ATE32728T1 (de) 1988-03-15
ES8601108A1 (es) 1985-10-16
DK332684D0 (da) 1984-07-06
IE841734L (en) 1985-01-07
CA1230069A (en) 1987-12-08
DE3324534A1 (de) 1985-01-17
GR82243B (en, 2012) 1984-12-13
DK165988B (da) 1993-02-22
DK332684A (da) 1985-01-08
JPH0670077B2 (ja) 1994-09-07
EP0134479A1 (de) 1985-03-20
US4636489A (en) 1987-01-13
IE57698B1 (en) 1993-03-10
EP0134479B1 (de) 1988-03-02
DK165988C (da) 1993-07-26
JPS60105699A (ja) 1985-06-11

Similar Documents

Publication Publication Date Title
ES534098A0 (es) Procedimiento para la obtencion de eglinas b o c modificadas
DK250181A (da) Fremgangsmaade til fremstilling af vinblastinderivater
ES2036737T3 (es) Procedimiento para la obtencion de mezclas farmaceuticas.
EE02962B1 (et) Mometasoonfuroaadi monohüdraat, selle valmistamismeetod ja farmatseutilised kompositsioonid
ES8801318A1 (es) Un procedimiento para la produccion de un peptido.
AU578050B2 (en) Desulfatohirudins, the preparation thereof and pharmaceutical compositions containing them
ES520988A0 (es) Procedimiento para la preparacion de nuevos 6,11-dihidro-dibenzo-(b,e)-tiepin-11-n-alcohilnorescopin-eteres.
ES518133A0 (es) Procedimiento para la preparacion de derivados de aminoacidos.
NO830110L (no) 6-substituert-s-triazolo(3,4-a)ftalazinderivater og fremgangsmaate for deres fremstilling
DK173883D0 (da) Substituerede 8-phenylxanthiner
PT79840B (en) Process for the preparation of polipeptides with alpha-amilase inhibiting action and pharmaceutical compositions therewith
IL64292A (en) D-homoandrostane-17alpha-carboxylic acids,derivatives thereof and 17alpha-spiroethers,their manufacture and pharmaceutical compositions containing them
ES519944A0 (es) Procedimiento para la preparacion de proteinas succiniladas que contienen hierro.
SE8505488D0 (sv) Isosilybinfri silibinin
FR2651435B1 (en, 2012)
PT71408A (de) Verfahren zur herstellung von 1-alkadien-2,4-yl-2-hidroxymethyl-3,4,5-trimydroxypiperidinen mit wirkung uber die kohlehydraten und/oder fettwechsel und von diesen verbindungen enthaltenden pharmazeutischen und/oder tierartzleichen praparaten
BG90414A (bg) 2-азабицикло (2,2,1)-хепт-5- ен-2-оцетна киселина и нейни производни, метод за получаване и приложението им
ES550285A0 (es) Procedimiento para preparar derivados de acidos aziridin-2- carboxilicos substituidos en n
NO160436C (no) Analogifremgangsmaate til fremstilling av farmasoeytisk anvendbare substituerte benzofenoner.
IT8348067A0 (it) Cianoguanidine, procedimento per ottenerle e composizioni farmaceutiche che le contengono
DE3162674D1 (en) A purified polypeptide, a process for its preparation, its use and pharmaceutical compositions containing it
FI810866A7 (fi) Substituoituja alkyylitioasyyliaminohappoja, niiden valmistusmenetelmiä ja farmaseuttfarmaseuttisia seoksia.
IT8323052A0 (it) N-(2-mercaptopropionil)glicina, derivati della procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.
JPS51136602A (en) Process for preparation of amino acid or peptide
MX154554A (es) Procedimiento para la preparacion de proteinas succiniladas que contienen hierro

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401