ES507043A0 - Un procedimiento para la preparacion de derivados de 2,4-diaminoquinazolina. - Google Patents
Un procedimiento para la preparacion de derivados de 2,4-diaminoquinazolina.Info
- Publication number
- ES507043A0 ES507043A0 ES507043A ES507043A ES507043A0 ES 507043 A0 ES507043 A0 ES 507043A0 ES 507043 A ES507043 A ES 507043A ES 507043 A ES507043 A ES 507043A ES 507043 A0 ES507043 A0 ES 507043A0
- Authority
- ES
- Spain
- Prior art keywords
- diaminoquinazoline
- derivatives
- procedure
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/44—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by —CHO groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C205/59—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/42—Oxygen atoms attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- C07D239/96—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/10—Seven-membered rings having the hetero atoms in positions 1 and 4 not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9031379A | 1979-11-01 | 1979-11-01 | |
US06/126,838 US4287341A (en) | 1979-11-01 | 1980-03-03 | Alkoxy-substituted-6-chloro-quinazoline-2,4-diones |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8207520A1 ES8207520A1 (es) | 1982-10-01 |
ES507043A0 true ES507043A0 (es) | 1982-10-01 |
Family
ID=26782146
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES496442A Expired ES8202334A1 (es) | 1979-11-01 | 1980-10-31 | Un procedimiento para la preparacion de derivados de 2,4-diaminoquinazolina |
ES507043A Granted ES507043A0 (es) | 1979-11-01 | 1981-11-11 | Un procedimiento para la preparacion de derivados de 2,4-diaminoquinazolina. |
ES507042A Expired ES8206491A1 (es) | 1979-11-01 | 1981-11-11 | Un procedimiento para la preparacion de derivados de 2,4-diaminoquinazolina. |
ES507041A Expired ES8303360A1 (es) | 1979-11-01 | 1981-11-11 | Un procedimiento para la preparacion de derivados de 2,4-diaminoquinazolina. |
ES516286A Expired ES8400415A1 (es) | 1979-11-01 | 1982-10-06 | "un procedimiento para la preparacion de derivados de 2,4-diaminoquinazolina". |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES496442A Expired ES8202334A1 (es) | 1979-11-01 | 1980-10-31 | Un procedimiento para la preparacion de derivados de 2,4-diaminoquinazolina |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES507042A Expired ES8206491A1 (es) | 1979-11-01 | 1981-11-11 | Un procedimiento para la preparacion de derivados de 2,4-diaminoquinazolina. |
ES507041A Expired ES8303360A1 (es) | 1979-11-01 | 1981-11-11 | Un procedimiento para la preparacion de derivados de 2,4-diaminoquinazolina. |
ES516286A Expired ES8400415A1 (es) | 1979-11-01 | 1982-10-06 | "un procedimiento para la preparacion de derivados de 2,4-diaminoquinazolina". |
Country Status (15)
Country | Link |
---|---|
US (1) | US4287341A (es) |
EP (1) | EP0028473B1 (es) |
AR (1) | AR227650A1 (es) |
AU (1) | AU520344B2 (es) |
CA (1) | CA1146546A (es) |
DE (1) | DE3069944D1 (es) |
DK (1) | DK153399C (es) |
ES (5) | ES8202334A1 (es) |
FI (1) | FI77455C (es) |
GR (1) | GR70728B (es) |
IE (1) | IE50366B1 (es) |
IL (1) | IL61375A (es) |
PH (3) | PH17552A (es) |
PT (1) | PT72007B (es) |
YU (1) | YU41745B (es) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4607034A (en) * | 1979-10-29 | 1986-08-19 | Mitsubishi Yuka Pharmaceutical Co., Ltd. | Quinazoline derivatives and pharmaceutical composition thereof |
GB2068961B (en) | 1980-02-13 | 1983-11-30 | Sankyo Co | Quinazoline derivatives |
US4351832A (en) * | 1980-04-18 | 1982-09-28 | American Home Products Corporation | 2-(Piperazinyl)-4-pyrimidinamines |
FI70411C (fi) | 1980-12-29 | 1986-09-19 | Pfizer | Foerfarande foer framstaellning av nya antihypertensiva 4-amino-6,7-dimetoxi-2-piperazinokinazolin derivat |
ES515338A0 (es) * | 1981-09-09 | 1983-11-01 | Orion Yhtymae Oy | "metodo para la preparacion de piperidinilquinazolidinas substituidas". |
GR79603B (es) * | 1982-07-24 | 1984-10-31 | Pfizer | |
CH651027A5 (de) * | 1982-11-12 | 1985-08-30 | Sandoz Ag | Heterocyclische verbindungen, ihre herstellung und verwendung. |
CS236097B1 (en) * | 1983-06-01 | 1985-05-15 | Jan Koenig | Acylderivatives of 2-piperazinochinazoline and method of their preparation |
US4933460A (en) * | 1983-08-22 | 1990-06-12 | Hoechst-Roussel Pharmaceuticals Inc. | Piperdine substituted phenyl hydrazones |
US4634769A (en) * | 1984-09-25 | 1987-01-06 | Ortho Pharmaceutical Corporation | Process for the preparation of 8-halo-5,6-dialkoxyquinazoline-2,4-diones and their salts |
FR2582513B1 (fr) * | 1985-05-28 | 1988-08-05 | Synthelabo | Compositions pharmaceutiques contenant de l'alfuzosine |
AT384218B (de) * | 1985-12-04 | 1987-10-12 | Gerot Pharmazeutika | Verfahren zur herstellung von neuen chinazolin-derivaten |
US4672116A (en) * | 1985-12-20 | 1987-06-09 | Ortho Pharmaceutical Corporation | Substituted 5,6-dialkoxyquinazoline derivatives |
US4668787A (en) * | 1985-12-20 | 1987-05-26 | Ortho Pharmaceutical Corporation | 5,6-dialkoxy-4-imino-2(1H)quinazolinone derivatives |
IL88507A (en) * | 1987-12-03 | 1993-02-21 | Smithkline Beckman Intercredit | 2,4-diaminoquinazolines, process for their preparation and pharmaceutical compositions comprising them |
EP0360936A1 (de) * | 1988-09-29 | 1990-04-04 | Siemens Aktiengesellschaft Österreich | Verfahren zur Wandlung des Abtastsignals eines analogen Eingangssignals |
EP0367888A1 (en) * | 1988-11-08 | 1990-05-16 | ISTITUTO LUSO FARMACO D'ITALIA S.p.A. | 2,2-Disubstituted 2,3-dihydro-1,4-benzodioxin derivatives having hypotensive activity |
GB8910722D0 (en) * | 1989-05-10 | 1989-06-28 | Smithkline Beckman Intercredit | Compounds |
CA2015981A1 (en) * | 1989-05-10 | 1990-11-10 | Thomas H. Brown | Compounds |
HUT64533A (en) * | 1990-11-06 | 1994-01-28 | Pfizer | Method for producing quinazoline derivatives for improving anti-tumoric activity and preparations containing said compounds |
PT100905A (pt) * | 1991-09-30 | 1994-02-28 | Eisai Co Ltd | Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem |
US5494908A (en) * | 1992-11-23 | 1996-02-27 | Hoechst-Roussel Pharmaceutical Incorporated | Substituted 3-(aminoalkylamino)-1,2-benzisoxazoles and related compounds |
IL108630A0 (en) * | 1993-02-18 | 1994-05-30 | Fmc Corp | Insecticidal substituted 2,4-diaminoquinazolines |
DE4429978A1 (de) * | 1994-08-24 | 1996-02-29 | Bayer Ag | Verfahren zur Herstellung von Chinazolin-2,4-dionen |
US5747490A (en) * | 1995-09-29 | 1998-05-05 | Merck & Co., Inc. | Alpha 1b adrenergic receptor antagonists |
WO1997020823A2 (en) * | 1995-12-01 | 1997-06-12 | Novartis Ag | 2-amino quinazoline derivatives as npy receptor antagonists |
CA2173408C (en) * | 1996-04-03 | 2001-09-04 | K.S. Keshava Murthy | Process for the manufacture of intermediates suitable to make doxazosin,terazosin, prazosin, tiodazosin and related antihypertensive medicines |
IT1286302B1 (it) * | 1996-04-10 | 1998-07-08 | Rotta Research Lab | Chinazoline-4-amino-2-(piperidino-1-il-4-sostituite) ad attivita' anti-ipertensiva, procedimento per la loro preparazione e loro uso |
GB9708917D0 (en) * | 1997-05-01 | 1997-06-25 | Pfizer Ltd | Compounds useful in therapy |
DZ3415A1 (fr) * | 2000-08-31 | 2002-03-07 | Chiron Corp | Guanidinobenzamides comme mc4-r agonistes. |
EP1385823B1 (en) * | 2001-04-09 | 2006-12-13 | Chiron Corporation | Guanidino compounds as melanocortin-4 receptor (mc4-r) agonists |
EP1487474A4 (en) * | 2002-02-25 | 2006-11-29 | Chiron Corp | INTRANASAL ADMINISTRATION OF MC4-R AGONISTS |
PT1551834E (pt) | 2002-05-23 | 2010-09-30 | Novartis Vaccines & Diagnostic | Compostos de quinazolinona substituídos |
EP1539754A4 (en) | 2002-08-23 | 2009-02-25 | Novartis Vaccines & Diagnostic | BENZIMIDAZOLE QUINOLINONES AND USES THEREOF |
PT2042504E (pt) | 2002-09-30 | 2011-09-07 | Bayer Schering Pharma Ag | Derivados da azolepirimidina fundida |
US6608200B1 (en) * | 2002-10-07 | 2003-08-19 | Council Of Scientific & Industrial Research | Process for the preparation of N-(2,3-Dihydrobenzo[1,4]dioxin-2-carbonyl)piperazine |
WO2004112793A1 (en) * | 2003-05-23 | 2004-12-29 | Chiron Corporation | Guanidino-substituted quinazolinone compounds as mc4-r agonists |
WO2005046589A2 (en) | 2003-11-07 | 2005-05-26 | Chiron Corporation | Pharmaceutically acceptable salts of quinolinone compounds having improved pharmaceutical properties |
KR20060105785A (ko) * | 2003-11-19 | 2006-10-11 | 카이론 코포레이션 | 감소된 생체축적을 갖는 퀴나졸리논 화합물 |
WO2006046593A1 (ja) * | 2004-10-27 | 2006-05-04 | Daiichi Sankyo Company, Limited | 2以上の置換基を有するベンゼン化合物 |
US8609672B2 (en) | 2010-08-27 | 2013-12-17 | University Of The Pacific | Piperazinylpyrimidine analogues as protein kinase inhibitors |
EP2640366A2 (en) | 2010-11-15 | 2013-09-25 | Exelixis, Inc. | Benzoxazepines as inhibitors of pi3k/mtor and methods of their use and manufacture |
GB202006382D0 (en) | 2020-04-30 | 2020-06-17 | Spermatech As | Use |
CN113105350B (zh) * | 2021-04-06 | 2023-11-24 | 利尔化学股份有限公司 | 制备2-氨基-3-烷基-5-氯苯甲酸的方法 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1117130B (de) * | 1959-10-14 | 1961-11-16 | Basf Ag | Verfahren zur Herstellung von 2, 4-Dihydroxychinazolinen |
US3511836A (en) * | 1967-12-13 | 1970-05-12 | Pfizer & Co C | 2,4,6,7-tetra substituted quinazolines |
US3669968A (en) * | 1970-05-21 | 1972-06-13 | Pfizer | Trialkoxy quinazolines |
DE2027645A1 (de) * | 1970-06-05 | 1971-12-09 | Byk Gulden Lomberg Chemische Fa bnk GmbH, 7750 Konstanz | Piperazinylalkyl chinazolon (4) den vate, Verfahren zu deren Herstellung und sie enthaltende Arzneimittel |
GB1334633A (en) * | 1972-04-07 | 1973-10-24 | Parke Davis & Co | Quinazoline compounds and methods for their production |
JPS4966691A (es) * | 1972-10-30 | 1974-06-27 | ||
US4026894A (en) * | 1975-10-14 | 1977-05-31 | Abbott Laboratories | Antihypertensive agents |
US4001237A (en) * | 1976-02-18 | 1977-01-04 | Bristol-Myers Company | Oxazole, isoxazole, thiazole and isothiazole amides |
US4060615A (en) * | 1976-02-18 | 1977-11-29 | Mead Johnson & Company | 2-Piperazinyl-6,7-dimethoxyquinazolines |
US4001238A (en) * | 1976-02-18 | 1977-01-04 | Bristol-Myers Company | 1,3,4-oxadiazole amides |
US4101548A (en) * | 1977-02-22 | 1978-07-18 | Bristol-Myers Company | 1,2,3-Thiadiazole amides |
US4102885A (en) * | 1977-06-20 | 1978-07-25 | Bristol-Myers Company | Process for preparing 2,4-dihaloquinazolines |
US4098788A (en) * | 1977-06-20 | 1978-07-04 | Bristol-Myers Company | Process for preparing quinazolines |
-
1980
- 1980-03-03 US US06/126,838 patent/US4287341A/en not_active Expired - Lifetime
- 1980-10-16 DE DE8080303658T patent/DE3069944D1/de not_active Expired
- 1980-10-16 EP EP80303658A patent/EP0028473B1/en not_active Expired
- 1980-10-29 PH PH24784A patent/PH17552A/en unknown
- 1980-10-29 AR AR283044A patent/AR227650A1/es active
- 1980-10-30 YU YU2775/80A patent/YU41745B/xx unknown
- 1980-10-30 FI FI803397A patent/FI77455C/fi not_active IP Right Cessation
- 1980-10-30 IL IL61375A patent/IL61375A/xx unknown
- 1980-10-30 CA CA000363579A patent/CA1146546A/en not_active Expired
- 1980-10-30 GR GR63246A patent/GR70728B/el unknown
- 1980-10-31 PT PT72007A patent/PT72007B/pt unknown
- 1980-10-31 ES ES496442A patent/ES8202334A1/es not_active Expired
- 1980-10-31 IE IE2258/80A patent/IE50366B1/en unknown
- 1980-10-31 AU AU63896/80A patent/AU520344B2/en not_active Ceased
- 1980-10-31 DK DK462380A patent/DK153399C/da not_active IP Right Cessation
-
1981
- 1981-11-11 ES ES507043A patent/ES507043A0/es active Granted
- 1981-11-11 ES ES507042A patent/ES8206491A1/es not_active Expired
- 1981-11-11 ES ES507041A patent/ES8303360A1/es not_active Expired
-
1982
- 1982-10-06 ES ES516286A patent/ES8400415A1/es not_active Expired
- 1982-10-08 PH PH27964A patent/PH20061A/en unknown
- 1982-10-08 PH PH27963A patent/PH18321A/en unknown
Also Published As
Publication number | Publication date |
---|---|
ES507041A0 (es) | 1983-02-01 |
YU277580A (en) | 1983-06-30 |
FI77455B (fi) | 1988-11-30 |
DK153399C (da) | 1988-12-19 |
EP0028473A1 (en) | 1981-05-13 |
GR70728B (es) | 1983-01-24 |
PT72007A (en) | 1980-11-01 |
EP0028473B1 (en) | 1985-01-09 |
FI803397L (fi) | 1981-05-02 |
ES8207520A1 (es) | 1982-10-01 |
PT72007B (en) | 1981-08-31 |
FI77455C (fi) | 1989-03-10 |
ES8303360A1 (es) | 1983-02-01 |
ES507042A0 (es) | 1982-08-16 |
ES8206491A1 (es) | 1982-08-16 |
DK153399B (da) | 1988-07-11 |
PH17552A (en) | 1984-09-20 |
YU41745B (en) | 1987-12-31 |
ES496442A0 (es) | 1982-01-16 |
IE802258L (en) | 1981-05-01 |
CA1146546A (en) | 1983-05-17 |
ES516286A0 (es) | 1983-10-16 |
AU6389680A (en) | 1981-05-07 |
PH18321A (en) | 1985-05-29 |
IE50366B1 (en) | 1986-04-02 |
AU520344B2 (en) | 1982-01-28 |
AR227650A1 (es) | 1982-11-30 |
ES8400415A1 (es) | 1983-10-16 |
DE3069944D1 (en) | 1985-02-21 |
IL61375A0 (en) | 1980-12-31 |
DK462380A (da) | 1981-05-02 |
IL61375A (en) | 1986-09-30 |
PH20061A (en) | 1986-09-18 |
ES8202334A1 (es) | 1982-01-16 |
US4287341A (en) | 1981-09-01 |
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