ES482002A1 - Procedimiento para la preparacion de nuevos derivados 5-fe- nilpirazolicos. - Google Patents
Procedimiento para la preparacion de nuevos derivados 5-fe- nilpirazolicos.Info
- Publication number
- ES482002A1 ES482002A1 ES482002A ES482002A ES482002A1 ES 482002 A1 ES482002 A1 ES 482002A1 ES 482002 A ES482002 A ES 482002A ES 482002 A ES482002 A ES 482002A ES 482002 A1 ES482002 A1 ES 482002A1
- Authority
- ES
- Spain
- Prior art keywords
- phenyl
- preparation
- salts
- processes
- pyrazole derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- OEDUIFSDODUDRK-UHFFFAOYSA-N 5-phenyl-1h-pyrazole Chemical class N1N=CC=C1C1=CC=CC=C1 OEDUIFSDODUDRK-UHFFFAOYSA-N 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- -1 alkyl radical Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 210000004185 liver Anatomy 0.000 abstract 1
- 230000007774 longterm Effects 0.000 abstract 1
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical compound [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
- C07D231/20—One oxygen atom attached in position 3 or 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
- C07D231/20—One oxygen atom attached in position 3 or 5
- C07D231/22—One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Procedimiento para la preparación de nuevos derivados 5- fenilpirazólicos de la fórmula I **(Fórmula)** en donde R1 y R2 pueden ser iguales o diferentes y significan un átomo de hidrógeno o de cloro o un grupo trifluorometilo, R3 es un átomo de hidrógeno, un radical fenilo, bencilo o alcohilo con 1 hasta 6 átomos de carbono, que puedo ser de cadena recta, ramificado o cíclico, R4 es un átomo de hidrógeno o radical metilo, R5 es un radical alcohilo con 1 hasta 4 átomos de carbono, de cadena recta o ramificado, y A es carboxilo, alcoxicarbonilo.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19782828529 DE2828529A1 (de) | 1978-06-29 | 1978-06-29 | Neue 5-phenylpyrazol-derivate, verfahren zu deren herstellung und arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES482002A1 true ES482002A1 (es) | 1980-03-01 |
Family
ID=6043086
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES482002A Expired ES482002A1 (es) | 1978-06-29 | 1979-06-28 | Procedimiento para la preparacion de nuevos derivados 5-fe- nilpirazolicos. |
| ES482004A Expired ES482004A1 (es) | 1978-06-29 | 1979-06-28 | Procedimiento para la preparacion de nuevos derivados 5-fe- nilpirazolicos. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES482004A Expired ES482004A1 (es) | 1978-06-29 | 1979-06-28 | Procedimiento para la preparacion de nuevos derivados 5-fe- nilpirazolicos. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0007019A1 (es) |
| JP (1) | JPS559078A (es) |
| DE (1) | DE2828529A1 (es) |
| DK (1) | DK273479A (es) |
| ES (2) | ES482002A1 (es) |
| PT (1) | PT69821A (es) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3132915A1 (de) * | 1981-08-20 | 1983-03-03 | Kali-Chemie Pharma Gmbh, 3000 Hannover | 1,5-diphenylpyrazolin-3-on-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| FR2513996A1 (fr) * | 1981-10-02 | 1983-04-08 | Nativelle Sa Ets | Derives du pyrazole, procede pour leur preparation et application en therapeutique |
| FR2529786A1 (fr) * | 1982-07-12 | 1984-01-13 | Nativelle Sa Ets | Compositions pharmaceutiques a base de derives de la pyrazolone-5, nouveaux produits et procede de preparation |
| US4550119A (en) * | 1983-05-23 | 1985-10-29 | Warner-Lambert Company | 2,4-Dihydro-5-[(substituted)phenyl]-4,4-disubstituted-3H-pyrazol-3-ones |
| DE3424586A1 (de) * | 1984-07-04 | 1986-01-09 | Kali-Chemie Pharma Gmbh, 3000 Hannover | 3-aminocarbonylmethoxy-5-phenyl-pyrazol-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| FR2659655B1 (fr) * | 1990-03-19 | 1992-07-24 | Union Pharma Scient Appl | Nouveaux derives d'oxypyrazole antagonistes des recepteurs a l'angiotensine ii ; leurs procedes de preparation, compositions pharmaceutiques les contenant. |
| DE4341749A1 (de) * | 1993-12-08 | 1995-06-14 | Kali Chemie Pharma Gmbh | 3-(Phenylalkylaminoalkyloxy)-5-phenylpyrazol- Verbindungen sowie Verfahren und Zwischenprodukte zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| US5547967A (en) * | 1993-12-08 | 1996-08-20 | Kali-Chemie Pharma Gmbh | (Phenylalkylaminoalkyloxy)-heteroaryl-compounds, processes and intermediates for their production and pharmaceutical compositions containing them |
| FR2773153A1 (fr) * | 1997-12-29 | 1999-07-02 | Rhone Poulenc Agrochimie | Nouveaux composes fongicides |
| CN102093344B (zh) * | 2011-03-17 | 2012-09-26 | 南京工业大学 | 一种含噻唑硫酮或噁唑烷酮的n-取代乙酰氧吡唑类化合物、制备方法及用途 |
| BR112021020565A2 (pt) | 2019-06-03 | 2021-12-21 | Bayer Ag | Ácidos 1-fenil-5-azinil pirazolil-3-oxialquílicos e seu uso para o controle do crescimento indesejado de plantas |
| BR112022011766A2 (pt) | 2019-12-19 | 2022-08-30 | Bayer Ag | Ácidos de 1,5-difenilpirazolil-3-oxialquila e ácidos de 1-fenil-5-tienilpirazolil-3-oxialquila e uso dos mesmos para controle de crescimento indesejado de planta |
| CA3181349A1 (en) | 2020-04-29 | 2021-11-04 | Bayer Aktiengesellschaft | 1-pyrazinylpyrazolyl-3-oxyalkyl acids and their derivatives, and their use for control of undesired plant growth |
| MX2023004617A (es) * | 2020-10-23 | 2023-05-09 | Bayer Ag | Derivados de 1-(piridil)-5-azinilpirazol y su uso para el combate del crecimiento de plantas no deseado. |
| ES3018232T3 (en) | 2020-11-05 | 2025-05-14 | Bayer Ag | Derivatives of [(1-phenyl-5-heteroaryl-1h-pyrazol-3-yl)oxy]acetic acid as safeners for the protection of cultivated plants |
| US20230389542A1 (en) * | 2020-11-05 | 2023-12-07 | Bayer Aktiengesellschaft | Use of [(1,5-diphenyl-1h-pyrazol-3-yl)oxy] acetic acid derivatives and their salts and compositions containing them, for reducing phytotoxic effects of agrochemicals, in particular of herbicides, in useful plants and crop plants |
| BR112023025695A2 (pt) | 2021-06-25 | 2024-02-27 | Bayer Ag | Ácidos (1,4,5-trissubstituídos-1h-pirazol-3-il)óxi-2-alcoxialquílicos e derivados dos mesmos, sais dos mesmos e uso dos mesmos como agentes herbicidas |
| EP4440314A1 (de) | 2021-12-01 | 2024-10-09 | Bayer Aktiengesellschaft | (1,4,5-trisubstituierte-1h-pyrazol-3-yl)oxy-2-alkylthio-alkylsäuren und -alkylsäure-derivate, deren salze und ihre verwendung als herbizide wirkstoffe |
| WO2024078871A1 (de) | 2022-10-14 | 2024-04-18 | Bayer Aktiengesellschaft | 1-pyridyl-5-phenylpyrazolyl-3-oxy- und -3-thioalkylsäuren und derivate und deren verwendung zur bekämpfung unerwünschten pflanzenwachstums |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2347015C2 (de) * | 1973-09-14 | 1985-12-12 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue Pyrazolyloxyessigsäurederivate, Verfahren zu ihrer Herstellung und diese enthaltende Mittel |
| DD118638A1 (es) * | 1975-04-10 | 1976-03-12 | ||
| DD135487A2 (de) * | 1977-03-14 | 1979-05-09 | Helmut Dorn | Verfahren zur herstellung neuer 3-(1-carboxy-alkoxy)-pyrazol-derivate |
| DE2809183C2 (de) * | 1977-03-14 | 1984-12-06 | Akademie Der Wissenschaften Der Ddr, Ddr 1199 Berlin | 3-(1-Carboxy-alkoxy)-pyrazol-Derivate und Verfahren zu ihrer Herstellung |
-
1978
- 1978-06-29 DE DE19782828529 patent/DE2828529A1/de not_active Withdrawn
-
1979
- 1979-01-26 PT PT69821A patent/PT69821A/pt unknown
- 1979-06-19 EP EP79102022A patent/EP0007019A1/de not_active Withdrawn
- 1979-06-28 DK DK273479A patent/DK273479A/da unknown
- 1979-06-28 ES ES482002A patent/ES482002A1/es not_active Expired
- 1979-06-28 ES ES482004A patent/ES482004A1/es not_active Expired
- 1979-06-29 JP JP8155879A patent/JPS559078A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DK273479A (da) | 1980-02-04 |
| PT69821A (en) | 1979-07-01 |
| EP0007019A1 (de) | 1980-01-23 |
| JPS559078A (en) | 1980-01-22 |
| ES482004A1 (es) | 1980-03-01 |
| DE2828529A1 (de) | 1980-01-17 |
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