ES482002A1 - Procedimiento para la preparacion de nuevos derivados 5-fe- nilpirazolicos. - Google Patents

Procedimiento para la preparacion de nuevos derivados 5-fe- nilpirazolicos.

Info

Publication number
ES482002A1
ES482002A1 ES482002A ES482002A ES482002A1 ES 482002 A1 ES482002 A1 ES 482002A1 ES 482002 A ES482002 A ES 482002A ES 482002 A ES482002 A ES 482002A ES 482002 A1 ES482002 A1 ES 482002A1
Authority
ES
Spain
Prior art keywords
preparation
nilpirazolicos
procedure
phenyl
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES482002A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AbbVie Pharmaceuticals GmbH
Original Assignee
Kali Chemie Pharma GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Pharma GmbH filed Critical Kali Chemie Pharma GmbH
Publication of ES482002A1 publication Critical patent/ES482002A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C07D231/20—One oxygen atom attached in position 3 or 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C07D231/20—One oxygen atom attached in position 3 or 5
    • C07D231/22—One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procedimiento para la preparación de nuevos derivados 5- fenilpirazólicos de la fórmula I **(Fórmula)** en donde R1 y R2 pueden ser iguales o diferentes y significan un átomo de hidrógeno o de cloro o un grupo trifluorometilo, R3 es un átomo de hidrógeno, un radical fenilo, bencilo o alcohilo con 1 hasta 6 átomos de carbono, que puedo ser de cadena recta, ramificado o cíclico, R4 es un átomo de hidrógeno o radical metilo, R5 es un radical alcohilo con 1 hasta 4 átomos de carbono, de cadena recta o ramificado, y A es carboxilo, alcoxicarbonilo.
ES482002A 1978-06-29 1979-06-28 Procedimiento para la preparacion de nuevos derivados 5-fe- nilpirazolicos. Expired ES482002A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782828529 DE2828529A1 (de) 1978-06-29 1978-06-29 Neue 5-phenylpyrazol-derivate, verfahren zu deren herstellung und arzneimittel

Publications (1)

Publication Number Publication Date
ES482002A1 true ES482002A1 (es) 1980-03-01

Family

ID=6043086

Family Applications (2)

Application Number Title Priority Date Filing Date
ES482004A Expired ES482004A1 (es) 1978-06-29 1979-06-28 Procedimiento para la preparacion de nuevos derivados 5-fe- nilpirazolicos.
ES482002A Expired ES482002A1 (es) 1978-06-29 1979-06-28 Procedimiento para la preparacion de nuevos derivados 5-fe- nilpirazolicos.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES482004A Expired ES482004A1 (es) 1978-06-29 1979-06-28 Procedimiento para la preparacion de nuevos derivados 5-fe- nilpirazolicos.

Country Status (6)

Country Link
EP (1) EP0007019A1 (es)
JP (1) JPS559078A (es)
DE (1) DE2828529A1 (es)
DK (1) DK273479A (es)
ES (2) ES482004A1 (es)
PT (1) PT69821A (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3132915A1 (de) * 1981-08-20 1983-03-03 Kali-Chemie Pharma Gmbh, 3000 Hannover 1,5-diphenylpyrazolin-3-on-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
FR2513996A1 (fr) * 1981-10-02 1983-04-08 Nativelle Sa Ets Derives du pyrazole, procede pour leur preparation et application en therapeutique
FR2529786A1 (fr) * 1982-07-12 1984-01-13 Nativelle Sa Ets Compositions pharmaceutiques a base de derives de la pyrazolone-5, nouveaux produits et procede de preparation
US4550119A (en) * 1983-05-23 1985-10-29 Warner-Lambert Company 2,4-Dihydro-5-[(substituted)phenyl]-4,4-disubstituted-3H-pyrazol-3-ones
DE3424586A1 (de) * 1984-07-04 1986-01-09 Kali-Chemie Pharma Gmbh, 3000 Hannover 3-aminocarbonylmethoxy-5-phenyl-pyrazol-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
FR2659655B1 (fr) * 1990-03-19 1992-07-24 Union Pharma Scient Appl Nouveaux derives d'oxypyrazole antagonistes des recepteurs a l'angiotensine ii ; leurs procedes de preparation, compositions pharmaceutiques les contenant.
US5547967A (en) * 1993-12-08 1996-08-20 Kali-Chemie Pharma Gmbh (Phenylalkylaminoalkyloxy)-heteroaryl-compounds, processes and intermediates for their production and pharmaceutical compositions containing them
DE4341749A1 (de) * 1993-12-08 1995-06-14 Kali Chemie Pharma Gmbh 3-(Phenylalkylaminoalkyloxy)-5-phenylpyrazol- Verbindungen sowie Verfahren und Zwischenprodukte zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
FR2773153A1 (fr) * 1997-12-29 1999-07-02 Rhone Poulenc Agrochimie Nouveaux composes fongicides
CN102093344B (zh) * 2011-03-17 2012-09-26 南京工业大学 一种含噻唑硫酮或噁唑烷酮的n-取代乙酰氧吡唑类化合物、制备方法及用途
CN114071999B (zh) 2019-06-03 2024-08-27 拜耳公司 1-苯基-5-吖嗪基吡唑基-3-氧基烷基酸及其用于控制不需要的植物生长的用途
BR112022007577A2 (pt) 2019-11-26 2022-07-12 Bayer Ag Derivados de ácido [(1,5-difenil-1h-1,2,4-triazol-3-il)óxi]acético e sais dos mesmos, composições de proteção de culturas compreendendo-os, métodos para produzi-los e uso dos mesmos para agentes de proteção
CA3164811A1 (en) 2019-12-19 2021-06-24 Bayer Aktiengesellschaft 1,5-diphenylpyrazolyl-3-oxyalkyl acids and 1-phenyl-5-thienylpyrazolyl-3-oxyalkyl acids and the use thereof for control of undesired plant growth
CA3181349A1 (en) 2020-04-29 2021-11-04 Bayer Aktiengesellschaft 1-pyrazinylpyrazolyl-3-oxyalkyl acids and their derivatives, and their use for control of undesired plant growth
CA3199303A1 (en) * 2020-10-23 2022-04-28 Bayer Aktiengesellschaft 1-(pyridyl)-5-azinylpyrazole derivatives, and their use for control of undesired plant growth
AU2021375253A1 (en) 2020-11-05 2023-06-08 Bayer Aktiengesellschaft [(5-phenyl-1-heteroaryl-1h-triazol-3-yl)oxy] acetic acid derivatives as safeners for the protection of useful plants and crop plants
ES3019943T3 (en) 2020-11-05 2025-05-21 Bayer Ag Derivatives of [(5-phenyl-1-heteroaryl-1h-pyrazol-3-yl)oxy]acetic acid as safeners for the protection of cultivated plants
US12606542B2 (en) 2020-11-05 2026-04-21 Bayer Aktiengesellschaft [(1,5-diheteroaryl-1H-1,2,4-triazol-3-yl)oxy] acetic acid derivatives as safeners for the protection of useful plants and crop plants
WO2022096450A1 (de) 2020-11-05 2022-05-12 Bayer Aktiengesellschaft Verwendung von [(1,5-diphenyl-1h-pyrazol-3-yl)oxy]essigsäure-derivaten und deren salze sowie diese enthaltende mittel, zur reduktion phytotoxischer wirkungen von agrochemikalien, insbesondere von herbiziden, in nutz- oder kulturpflanzen.
JP2023548352A (ja) 2020-11-05 2023-11-16 バイエル・アクチエンゲゼルシヤフト 有用植物および作物植物の保護のための毒性緩和剤としての［（１－フェニル－５－（ヘテロアリール）－１ｈ－１，２，４－トリアゾール－３－イル）オキシ］酢酸誘導体
CN116709916B (zh) 2020-11-05 2026-03-24 拜耳公司 作为保护有用植物和作物植物的安全剂的[(1-苯基-5-杂芳基-1h-吡唑-3-基)氧基]乙酸衍生物
WO2022268933A1 (de) 2021-06-25 2022-12-29 Bayer Aktiengesellschaft (1,4,5-trisubstituierte-1h-pyrazol-3-yl)oxy-2-alkoxy-alkylsäuren und -alkylsäure-derivate, deren salze und ihre verwendung als herbizide wirkstoffe
US20250026724A1 (en) 2021-12-01 2025-01-23 Bayer Aktiengesellschaft (1,4,5-trisubstituted 1h-pyrazol-3-yl)oxy-2-alkylthioalkyl acids and -alkyl acid derivatives, salts thereof and use thereof as active herbicidal ingredients
WO2024078871A1 (de) 2022-10-14 2024-04-18 Bayer Aktiengesellschaft 1-pyridyl-5-phenylpyrazolyl-3-oxy- und -3-thioalkylsäuren und derivate und deren verwendung zur bekämpfung unerwünschten pflanzenwachstums

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2347015C2 (de) * 1973-09-14 1985-12-12 Schering AG, 1000 Berlin und 4709 Bergkamen Neue Pyrazolyloxyessigsäurederivate, Verfahren zu ihrer Herstellung und diese enthaltende Mittel
DD118638A1 (es) * 1975-04-10 1976-03-12
DE2809183C2 (de) * 1977-03-14 1984-12-06 Akademie Der Wissenschaften Der Ddr, Ddr 1199 Berlin 3-(1-Carboxy-alkoxy)-pyrazol-Derivate und Verfahren zu ihrer Herstellung
DD135487A2 (de) * 1977-03-14 1979-05-09 Helmut Dorn Verfahren zur herstellung neuer 3-(1-carboxy-alkoxy)-pyrazol-derivate

Also Published As

Publication number Publication date
DK273479A (da) 1980-02-04
EP0007019A1 (de) 1980-01-23
PT69821A (en) 1979-07-01
JPS559078A (en) 1980-01-22
DE2828529A1 (de) 1980-01-17
ES482004A1 (es) 1980-03-01

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