ES481129A1 - Procedimiento para la preparacion de nuevos derivados fenil-piperazinicos. - Google Patents
Procedimiento para la preparacion de nuevos derivados fenil-piperazinicos.Info
- Publication number
- ES481129A1 ES481129A1 ES481129A ES481129A ES481129A1 ES 481129 A1 ES481129 A1 ES 481129A1 ES 481129 A ES481129 A ES 481129A ES 481129 A ES481129 A ES 481129A ES 481129 A1 ES481129 A1 ES 481129A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- new substituted
- phenylpiperazine derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedimiento para la preparación de nuevos derivados finilpiperazínicos de la fórmula **(Fórmula)** donde R1 significa hidrógeno o un grupo alcohico C1-C6, R2 significa hidrógeno o uno o varios sustituyentes, iguales o diferentes, con el siguiente significado; alcohilo C1-C6, alcoxi C1-C6, halógeno, trifluorometilo, hidroxi, nitro, amino, metilendioxi, R3 significa hidrógeno, hidroxi, alcanoiloxi C1-C6, así como sus sales fisiológicamente compatibles y n significa 1 ó 2.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19782824677 DE2824677A1 (de) | 1978-06-06 | 1978-06-06 | Neue substituierte phenylpiperazinderivate und verfahren zu deren herstellung |
DE19782853996 DE2853996A1 (de) | 1978-12-14 | 1978-12-14 | Neue substituierte phenylpiperazinderivate und verfahren zu deren herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
ES481129A1 true ES481129A1 (es) | 1979-11-16 |
Family
ID=25774636
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES481126A Expired ES481126A1 (es) | 1978-06-06 | 1979-05-31 | Procedimiento para la preparacion de nuevos derivados fe- nilpiperazinicos. |
ES481128A Expired ES481128A1 (es) | 1978-06-06 | 1979-05-31 | Procedimiento para la preparacion de nuevos derivados fenil-piperazinicos. |
ES481129A Expired ES481129A1 (es) | 1978-06-06 | 1979-05-31 | Procedimiento para la preparacion de nuevos derivados fenil-piperazinicos. |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES481126A Expired ES481126A1 (es) | 1978-06-06 | 1979-05-31 | Procedimiento para la preparacion de nuevos derivados fe- nilpiperazinicos. |
ES481128A Expired ES481128A1 (es) | 1978-06-06 | 1979-05-31 | Procedimiento para la preparacion de nuevos derivados fenil-piperazinicos. |
Country Status (5)
Country | Link |
---|---|
US (1) | US4234584A (es) |
EP (1) | EP0005828B1 (es) |
AU (1) | AU4776179A (es) |
DE (1) | DE2960178D1 (es) |
ES (3) | ES481126A1 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS54130587A (en) * | 1978-03-30 | 1979-10-09 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivative |
EP0025111B1 (en) * | 1979-08-10 | 1984-07-25 | Sandoz Ag | 3-aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them |
PH17194A (en) * | 1980-03-06 | 1984-06-19 | Otsuka Pharma Co Ltd | Novel carbostyril derivatives,and pharmaceutical composition containing the same |
DE3200304A1 (de) * | 1981-01-16 | 1982-08-26 | Sandoz-Patent-GmbH, 7850 Lörrach | 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel |
DE3424685A1 (de) * | 1984-07-05 | 1986-02-06 | Beiersdorf Ag, 2000 Hamburg | Neue substituierte phenylpiperazinyl-propanole, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen |
DE3426419A1 (de) * | 1984-07-18 | 1986-01-23 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue oxindol-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und zwischenprodukte |
GB2163150B (en) * | 1984-07-19 | 1988-05-25 | Sandoz Ltd | 3-aminopropoxyaryl derivatives |
CN85108214A (zh) * | 1984-11-22 | 1986-08-20 | 赫彻斯特股份公司 | 新的取代的苯基哌嗪衍生物及其药物的制造方法 |
DE3529994A1 (de) * | 1985-08-22 | 1987-02-26 | Hoechst Ag | Indolinonderivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung |
FR2589863B1 (fr) * | 1985-11-12 | 1988-07-29 | Sanofi Sa | Derives d'hydroxy-4 indole, leur procede de preparation et leur utilisation |
US5006528A (en) * | 1988-10-31 | 1991-04-09 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
MX2007012083A (es) * | 2005-04-01 | 2007-11-20 | Warner Lambert Co | Tetrahidro-piridoazepin-8-onas y compuestos relacionados para el tratamiento de la esquizofrenia. |
TWI320783B (en) | 2005-04-14 | 2010-02-21 | Otsuka Pharma Co Ltd | Heterocyclic compound |
AR055203A1 (es) * | 2005-08-31 | 2007-08-08 | Otsuka Pharma Co Ltd | Derivados de benzotiofeno con propiedades antipsicoticas |
CA2722776A1 (en) * | 2008-05-09 | 2009-11-12 | Emory University | Nmda receptor antagonists for the treatment of neuropsychiatric disorders |
HRP20171415T4 (hr) | 2009-06-25 | 2023-03-03 | Alkermes Pharma Ireland Limited | Heterociklični spojevi za liječenje neuroloških i psiholoških poremećaja |
ES2834973T3 (es) | 2010-05-04 | 2021-06-21 | Alkermes Pharma Ireland Ltd | Procedimiento de síntesis de compuestos de lactama oxidada |
EP2585066B1 (en) | 2010-06-24 | 2018-09-26 | Alkermes Pharma Ireland Limited | Prodrugs of nh-acidic compounds: ester, carbonate, carbamate and phosphonate derivatives |
JP7384812B2 (ja) | 2018-03-05 | 2023-11-21 | アルカームス ファーマ アイルランド リミテッド | アリピプラゾール投与戦略 |
TWI820847B (zh) * | 2021-08-05 | 2023-11-01 | 大陸商上海樞境生物科技有限公司 | 含三并環類衍生物調節劑、其製備方法和應用 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH534687A (de) * | 1968-07-05 | 1973-03-15 | Cassella Farbwerke Mainkur Ag | Verfahren zur Herstellung von Derivaten des 2-Oxo-1,2-dihydro-chinolins |
JPS48103590A (es) * | 1972-04-13 | 1973-12-25 | ||
US3910924A (en) * | 1972-04-13 | 1975-10-07 | Otsuka Pharma Co Ltd | 3,4-Dihydrocarbostyril derivatives and a process for preparing the same |
DE2263211A1 (de) * | 1972-12-23 | 1974-07-04 | Boehringer Sohn Ingelheim | Neue arylpiperazine und verfahren zu ihrer herstellung |
DE2337461A1 (de) * | 1973-07-24 | 1975-02-06 | Boehringer Mannheim Gmbh | Neue indolderivate und verfahren zu deren herstellung |
DE2525656A1 (de) * | 1974-06-19 | 1976-01-15 | Sandoz Ag | Verfahren zur herstellung neuer heterocyclischer verbindungen |
DE2719562C2 (de) * | 1976-05-08 | 1986-05-07 | Otsuka Pharmaceutical Co. Ltd., Tokio/Tokyo | 3, 4-Dihydrocarbostyrilderivate, Verfahren zu deren Herstellung und Arzneimittel, welche diese enthalten |
DE2737630A1 (de) * | 1977-08-20 | 1979-03-01 | Boehringer Mannheim Gmbh | Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
-
1979
- 1979-05-30 EP EP79101654A patent/EP0005828B1/de not_active Expired
- 1979-05-30 DE DE7979101654T patent/DE2960178D1/de not_active Expired
- 1979-05-31 ES ES481126A patent/ES481126A1/es not_active Expired
- 1979-05-31 ES ES481128A patent/ES481128A1/es not_active Expired
- 1979-05-31 ES ES481129A patent/ES481129A1/es not_active Expired
- 1979-06-04 US US06/044,948 patent/US4234584A/en not_active Expired - Lifetime
- 1979-06-05 AU AU47761/79A patent/AU4776179A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP0005828B1 (de) | 1981-03-11 |
AU4776179A (en) | 1979-12-13 |
ES481128A1 (es) | 1979-11-16 |
US4234584A (en) | 1980-11-18 |
EP0005828A1 (de) | 1979-12-12 |
ES481126A1 (es) | 1979-11-16 |
DE2960178D1 (en) | 1981-04-09 |
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