ATE46172T1 - Verbindungen, diese enthaltende pharmazeutische zusammensetzungen und verfahren zur herstellung. - Google Patents

Verbindungen, diese enthaltende pharmazeutische zusammensetzungen und verfahren zur herstellung.

Info

Publication number
ATE46172T1
ATE46172T1 AT83111894T AT83111894T ATE46172T1 AT E46172 T1 ATE46172 T1 AT E46172T1 AT 83111894 T AT83111894 T AT 83111894T AT 83111894 T AT83111894 T AT 83111894T AT E46172 T1 ATE46172 T1 AT E46172T1
Authority
AT
Austria
Prior art keywords
compounds
manufacture
pharmaceutical compositions
compositions containing
substituents
Prior art date
Application number
AT83111894T
Other languages
English (en)
Inventor
Huang Fu-Chih
Howard Jones
Chan Wan-Kit
Original Assignee
Rorer Int Overseas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rorer Int Overseas filed Critical Rorer Int Overseas
Application granted granted Critical
Publication of ATE46172T1 publication Critical patent/ATE46172T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C241/00—Preparation of compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C241/02—Preparation of hydrazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/26—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C243/34—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a carbon skeleton further substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/80—Antihypertensive peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Earth Drilling (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT83111894T 1982-11-29 1983-11-28 Verbindungen, diese enthaltende pharmazeutische zusammensetzungen und verfahren zur herstellung. ATE46172T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/445,117 US4482544A (en) 1982-11-29 1982-11-29 Compounds for treating hypertension
EP83111894A EP0112511B1 (de) 1982-11-29 1983-11-28 Verbindungen, diese enthaltende pharmazeutische Zusammensetzungen und Verfahren zur Herstellung

Publications (1)

Publication Number Publication Date
ATE46172T1 true ATE46172T1 (de) 1989-09-15

Family

ID=23767670

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83111894T ATE46172T1 (de) 1982-11-29 1983-11-28 Verbindungen, diese enthaltende pharmazeutische zusammensetzungen und verfahren zur herstellung.

Country Status (15)

Country Link
US (1) US4482544A (de)
EP (1) EP0112511B1 (de)
JP (1) JPS59108752A (de)
KR (1) KR840007563A (de)
AT (1) ATE46172T1 (de)
AU (1) AU2176183A (de)
CA (1) CA1249394A (de)
DE (1) DE3380517D1 (de)
ES (1) ES527854A0 (de)
FI (1) FI834362A (de)
IL (1) IL70342A0 (de)
NO (1) NO834387L (de)
NZ (1) NZ206433A (de)
PH (1) PH19870A (de)
ZA (1) ZA838855B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4666906A (en) * 1983-03-16 1987-05-19 Usv Pharmaceutical Corporation Compounds for treating hypertension
US4596791A (en) * 1983-03-16 1986-06-24 Usv Pharmaceutical Corp. Compounds for treating hypertension
AU2859984A (en) * 1983-05-23 1984-11-29 Usv Pharmaceutical Corp. Compounds for treating hypertension
EP0137746A3 (de) * 1983-09-22 1986-01-08 FISONS plc Stickstoffhaltige substituierte Inhibitoren vom Angiotensin-Umwandlungs-Enzym
DE3569368D1 (en) * 1984-11-30 1989-05-18 Fisons Plc Angiotensin converting enzyme inhibitors and their production and use as pharmaceuticals
SE8803847A0 (sv) * 1988-10-27 1990-04-28 Kabigen Ab Neuromodulerande peptid
US5989440A (en) * 1996-11-28 1999-11-23 Kurita Water Industries Ltd. Method of using oxygen scavenger and removing oxygen from water

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
AU556932B2 (en) * 1981-03-30 1986-11-27 Usv Pharmaceutical Corp. Dipetide with heterocyclic groiup
US4820729A (en) * 1981-03-30 1989-04-11 Rorer Pharmaceutical Corporation N-substituted-amido-amino acids
FI841052A (fi) * 1983-03-16 1984-09-17 Usv Pharma Corp Foereningar foer behandling av blodtryckssjukdomar.

Also Published As

Publication number Publication date
EP0112511B1 (de) 1989-09-06
CA1249394A (en) 1989-01-24
KR840007563A (ko) 1984-12-08
AU2176183A (en) 1984-06-07
US4482544A (en) 1984-11-13
ES8507472A1 (es) 1985-10-01
EP0112511A3 (en) 1985-11-13
DE3380517D1 (en) 1989-10-12
EP0112511A2 (de) 1984-07-04
NO834387L (no) 1984-05-30
FI834362A (fi) 1984-05-30
NZ206433A (en) 1986-07-11
JPS59108752A (ja) 1984-06-23
ES527854A0 (es) 1985-10-01
FI834362A0 (fi) 1983-11-29
ZA838855B (en) 1984-07-25
IL70342A0 (en) 1984-02-29
PH19870A (en) 1986-08-13

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties