ZA838855B - Compounds for treating hypertension - Google Patents

Compounds for treating hypertension

Info

Publication number
ZA838855B
ZA838855B ZA838855A ZA838855A ZA838855B ZA 838855 B ZA838855 B ZA 838855B ZA 838855 A ZA838855 A ZA 838855A ZA 838855 A ZA838855 A ZA 838855A ZA 838855 B ZA838855 B ZA 838855B
Authority
ZA
South Africa
Prior art keywords
compounds
treating hypertension
substituents
pharmaceutically
image
Prior art date
Application number
ZA838855A
Other languages
English (en)
Inventor
Fu-Chih Huang
Howard Jones
Wan-Kit Chan
Original Assignee
Usv Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Usv Pharma Corp filed Critical Usv Pharma Corp
Publication of ZA838855B publication Critical patent/ZA838855B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C241/00—Preparation of compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C241/02—Preparation of hydrazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/26—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C243/34—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a carbon skeleton further substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/80—Antihypertensive peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Earth Drilling (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ZA838855A 1982-11-29 1983-11-28 Compounds for treating hypertension ZA838855B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/445,117 US4482544A (en) 1982-11-29 1982-11-29 Compounds for treating hypertension

Publications (1)

Publication Number Publication Date
ZA838855B true ZA838855B (en) 1984-07-25

Family

ID=23767670

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA838855A ZA838855B (en) 1982-11-29 1983-11-28 Compounds for treating hypertension

Country Status (15)

Country Link
US (1) US4482544A (de)
EP (1) EP0112511B1 (de)
JP (1) JPS59108752A (de)
KR (1) KR840007563A (de)
AT (1) ATE46172T1 (de)
AU (1) AU2176183A (de)
CA (1) CA1249394A (de)
DE (1) DE3380517D1 (de)
ES (1) ES8507472A1 (de)
FI (1) FI834362A (de)
IL (1) IL70342A0 (de)
NO (1) NO834387L (de)
NZ (1) NZ206433A (de)
PH (1) PH19870A (de)
ZA (1) ZA838855B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4596791A (en) * 1983-03-16 1986-06-24 Usv Pharmaceutical Corp. Compounds for treating hypertension
US4666906A (en) * 1983-03-16 1987-05-19 Usv Pharmaceutical Corporation Compounds for treating hypertension
ZA843899B (en) * 1983-05-23 1984-12-24 Usv Pharma Corp Compounds for treating hypertension
EP0137746A3 (de) * 1983-09-22 1986-01-08 FISONS plc Stickstoffhaltige substituierte Inhibitoren vom Angiotensin-Umwandlungs-Enzym
DE3569368D1 (en) * 1984-11-30 1989-05-18 Fisons Plc Angiotensin converting enzyme inhibitors and their production and use as pharmaceuticals
SE8803847A0 (sv) * 1988-10-27 1990-04-28 Kabigen Ab Neuromodulerande peptid
US5989440A (en) * 1996-11-28 1999-11-23 Kurita Water Industries Ltd. Method of using oxygen scavenger and removing oxygen from water

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
US4820729A (en) * 1981-03-30 1989-04-11 Rorer Pharmaceutical Corporation N-substituted-amido-amino acids
AU556932B2 (en) * 1981-03-30 1986-11-27 Usv Pharmaceutical Corp. Dipetide with heterocyclic groiup
FI841052A (fi) * 1983-03-16 1984-09-17 Usv Pharma Corp Foereningar foer behandling av blodtryckssjukdomar.

Also Published As

Publication number Publication date
DE3380517D1 (en) 1989-10-12
PH19870A (en) 1986-08-13
ES527854A0 (es) 1985-10-01
EP0112511B1 (de) 1989-09-06
FI834362A (fi) 1984-05-30
US4482544A (en) 1984-11-13
NZ206433A (en) 1986-07-11
NO834387L (no) 1984-05-30
AU2176183A (en) 1984-06-07
ES8507472A1 (es) 1985-10-01
EP0112511A3 (en) 1985-11-13
CA1249394A (en) 1989-01-24
JPS59108752A (ja) 1984-06-23
IL70342A0 (en) 1984-02-29
FI834362A0 (fi) 1983-11-29
KR840007563A (ko) 1984-12-08
ATE46172T1 (de) 1989-09-15
EP0112511A2 (de) 1984-07-04

Similar Documents

Publication Publication Date Title
ES8206440A1 (es) Un procedimiento para la preparacion del enantiomero (-) de la n-metil-3-(2metilfenoxi)-3-fenilpropilamina.
CS650083A2 (en) Herbicidni prostredek a zpusob vyroby ucinne slozky
ES525692A0 (es) Procedimiento para la obtencion de dihidropirimidinas
AU561450B2 (en) 2-amino-3-acylamino-6-benzylamino pyridine derivatives
PH19870A (en) Compounds for treating hypertension
ES8602631A1 (es) Procedimiento de producir compuestos para tratar la hipertension
ES2018208B3 (es) Derivados de hidroxipirazol, procedimiento para su obtencion y su aplicacion contra microorganismos.
ES8405779A1 (es) Un procedimiento para preparar derivados de 1-fenoxi-3-(4-fenilpiperazino)-2-propanol.
EP0127124A3 (de) Verbindungen zur Behandlung von hohem Blutdruck
ES538576A0 (es) Procedimiento para la obtencion de derivados de arilamina
AU555274B2 (en) N-2 substituted derivatives of 2,4-diamino-5-benzyl- pyrimidine
CS127484A2 (en) Zpusob vyroby n ( trifluormethylfenyl) n propargylpipera zinu
ZA8312B (en) Substituted 1-benzoyl-2-phenyliminiomidazolidine derivatives
DE3460024D1 (en) Aminopropanol derivatives of 1-(2-hydroxyphenyl)-3-phenyl propanols, method for their manufacture and therapeutic agents containing these compounds
SE8403112D0 (sv) 1-phenoxy-3-hydroxylindolylalkylamino-3-propanols and preparation
DE3674060D1 (de) Pharmacologisch aktive propionylanilide.