ES474156A1 - Un procedimiento para preparar un compuesto seleccionado delgrupo formado por alquiltiofenoxipropanolamina - Google Patents
Un procedimiento para preparar un compuesto seleccionado delgrupo formado por alquiltiofenoxipropanolaminaInfo
- Publication number
- ES474156A1 ES474156A1 ES474156A ES474156A ES474156A1 ES 474156 A1 ES474156 A1 ES 474156A1 ES 474156 A ES474156 A ES 474156A ES 474156 A ES474156 A ES 474156A ES 474156 A1 ES474156 A1 ES 474156A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- alkylthiophenoxypropanolamines
- cycloalkyl
- administered
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000017531 blood circulation Effects 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 230000007812 deficiency Effects 0.000 abstract 1
- 210000002464 muscle smooth vascular Anatomy 0.000 abstract 1
- 230000000414 obstructive effect Effects 0.000 abstract 1
- 210000005259 peripheral blood Anatomy 0.000 abstract 1
- 239000011886 peripheral blood Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/31—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/32—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to an acyclic carbon atom of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Un procedimiento para preparar un compuesto seleccionado del grupo formado por una alquiltiofenoxipropanolamina de fórmula (* ver fórmula) y sus sales por adición de ácido correspondientes, donde A y B son hidrógeno, R está seleccionado, independientemente, de un grupo formado por hidrógeno y alquilo inferior de 1 a 4 átomos de carbón inclusive; R1 representa un grupo alquilo de 1 a 8 átomos de carbono, inclusive; R2 representa un grupo alquilo de 6 a 12 átomos de carbono, inclusive, o cicloalquilo, teniendo de 5 a 8 átomos de carbono en el anillo y de 2 a 6 átomos de carbono en la cadena alquilénica.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84116877A | 1977-10-11 | 1977-10-11 | |
| US94222278A | 1978-09-14 | 1978-09-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES474156A1 true ES474156A1 (es) | 1979-10-16 |
Family
ID=27126241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES474156A Expired ES474156A1 (es) | 1977-10-11 | 1978-10-11 | Un procedimiento para preparar un compuesto seleccionado delgrupo formado por alquiltiofenoxipropanolamina |
Country Status (21)
| Country | Link |
|---|---|
| JP (1) | JPS6049188B2 (es) |
| AR (2) | AR224239A1 (es) |
| AU (1) | AU520181B2 (es) |
| CA (1) | CA1116636A (es) |
| CH (1) | CH642349A5 (es) |
| DE (1) | DE2844353C2 (es) |
| DK (1) | DK146005C (es) |
| ES (1) | ES474156A1 (es) |
| FI (1) | FI70883C (es) |
| FR (1) | FR2405932A1 (es) |
| GB (1) | GB2006197B (es) |
| GR (1) | GR73919B (es) |
| IE (1) | IE47449B1 (es) |
| IL (1) | IL55695A (es) |
| IT (1) | IT1109310B (es) |
| LU (1) | LU80345A1 (es) |
| NL (1) | NL7810156A (es) |
| NO (1) | NO146161C (es) |
| PH (1) | PH15824A (es) |
| SE (1) | SE443782B (es) |
| YU (1) | YU41602B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4396629A (en) | 1980-12-29 | 1983-08-02 | Sterling Drug Inc. | Compositions, processes and method |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6504268A (es) * | 1965-04-03 | 1966-10-04 | ||
| DE2551141A1 (de) * | 1975-11-14 | 1977-05-18 | Dolorgiet Arzneimittelfabrik | Cyclododecylamin-derivate |
| DE2552266A1 (de) * | 1975-11-21 | 1977-05-26 | Dolorgiet Arzneimittelfabrik | Cyclohexylamin-derivate |
-
1978
- 1978-09-26 CA CA000312115A patent/CA1116636A/en not_active Expired
- 1978-09-26 GR GR57313A patent/GR73919B/el unknown
- 1978-10-02 GB GB7838985A patent/GB2006197B/en not_active Expired
- 1978-10-04 AU AU40393/78A patent/AU520181B2/en not_active Expired
- 1978-10-04 AR AR273952A patent/AR224239A1/es active
- 1978-10-06 YU YU2352/78A patent/YU41602B/xx unknown
- 1978-10-09 IL IL55695A patent/IL55695A/xx unknown
- 1978-10-09 NL NL7810156A patent/NL7810156A/xx not_active Application Discontinuation
- 1978-10-09 FI FI783068A patent/FI70883C/fi not_active IP Right Cessation
- 1978-10-10 DK DK450978A patent/DK146005C/da not_active IP Right Cessation
- 1978-10-10 FR FR7828916A patent/FR2405932A1/fr active Granted
- 1978-10-10 IT IT51437/78A patent/IT1109310B/it active
- 1978-10-10 PH PH21691A patent/PH15824A/en unknown
- 1978-10-10 LU LU80345A patent/LU80345A1/xx unknown
- 1978-10-10 IE IE2018/78A patent/IE47449B1/en unknown
- 1978-10-10 SE SE7810574A patent/SE443782B/sv not_active IP Right Cessation
- 1978-10-10 NO NO783416A patent/NO146161C/no unknown
- 1978-10-11 ES ES474156A patent/ES474156A1/es not_active Expired
- 1978-10-11 JP JP53124219A patent/JPS6049188B2/ja not_active Expired
- 1978-10-11 DE DE2844353A patent/DE2844353C2/de not_active Expired
- 1978-10-11 CH CH1056478A patent/CH642349A5/de not_active IP Right Cessation
-
1979
- 1979-10-31 AR AR278713A patent/AR223016A1/es active
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20001204 |