ES471845A1 - Procedimiento de produccion de l-carnitina - Google Patents

Procedimiento de produccion de l-carnitina

Info

Publication number
ES471845A1
ES471845A1 ES471845A ES471845A ES471845A1 ES 471845 A1 ES471845 A1 ES 471845A1 ES 471845 A ES471845 A ES 471845A ES 471845 A ES471845 A ES 471845A ES 471845 A1 ES471845 A1 ES 471845A1
Authority
ES
Spain
Prior art keywords
carnitine
coenzyme
enzymatic synthesis
dehydrocarnitine
dehydrogenase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES471845A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IFP Energies Nouvelles IFPEN
Original Assignee
IFP Energies Nouvelles IFPEN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IFP Energies Nouvelles IFPEN filed Critical IFP Energies Nouvelles IFPEN
Publication of ES471845A1 publication Critical patent/ES471845A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/007—Carnitine; Butyrobetaine; Crotonobetaine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01108—Carnitine 3-dehydrogenase (1.1.1.108)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/874—Pseudomonas
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/874—Pseudomonas
    • Y10S435/875—Pseudomonas aeruginosa
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/874—Pseudomonas
    • Y10S435/876—Pseudomonas fluorescens
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/874—Pseudomonas
    • Y10S435/877—Pseudomonas putida

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Procedimiento de producción de L-carnitina, que consiste en someter la 3-deshidrocarnitina o una de sus sales a la acción simultánea, en medio acuoso, de: a) la carnitina deshidrogenasa, b) un coenzima utilizable por la deshidrocarnitina y c) un agente reductor del coenzima utilizado.
ES471845A 1977-07-18 1978-07-18 Procedimiento de produccion de l-carnitina Expired ES471845A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7722183A FR2398046A1 (fr) 1977-07-18 1977-07-18 Synthese enzymatique de la l-carnitine

Publications (1)

Publication Number Publication Date
ES471845A1 true ES471845A1 (es) 1979-02-01

Family

ID=9193544

Family Applications (1)

Application Number Title Priority Date Filing Date
ES471845A Expired ES471845A1 (es) 1977-07-18 1978-07-18 Procedimiento de produccion de l-carnitina

Country Status (5)

Country Link
US (1) US4221869A (es)
CH (1) CH634878A5 (es)
ES (1) ES471845A1 (es)
FR (1) FR2398046A1 (es)
IT (1) IT1097009B (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2930087A1 (de) * 1979-07-25 1981-02-26 Biotechnolog Forschung Gmbh Verfahren zur kontinuierlichen enzymatischen umwandlung von wasserloeslichen alpha -ketocarbonsaeuren in die entsprechenden alpha -hydroxycarbonsaeuren
DE2930070A1 (de) * 1979-07-25 1981-02-19 Biotechnolog Forschung Gmbh Verfahren zur kontinuierlichen enzymatischen umwandlung von wasserloeslichen alpha -ketocarbonsaeuren in die entsprechenden aminosaeuren
IT1142201B (it) * 1980-06-24 1986-10-08 Sigma Tau Ind Farmaceuti Procedimento per la produzione enzimatica di l-carnitina
FR2526442B1 (fr) * 1982-05-06 1985-09-27 Inst Francais Du Petrole Production de glucose deshydrogenase et utilisation de l'enzyme obtenu dans la synthese enzymatique de la l-carnitine
JPS59192095A (ja) * 1983-04-13 1984-10-31 Ajinomoto Co Inc Ｌ−カルニチンの製造法
DE3326546A1 (de) * 1983-07-22 1985-02-07 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., 8000 München Verfahren zur kontinuierlichen enzymatischen herstellung von gluconsaeure oder ihren derivaten und sorbit und/oder mannit
ZA852808B (en) * 1984-04-20 1985-11-27 Wisconsin Alumni Res Found Process for preparing l-carnitine
US4751182A (en) * 1984-04-20 1988-06-14 Wisconsin Alumni Research Foundation Process for preparing L-carnitine from DL-carnitine
FR2605316B1 (fr) * 1986-04-04 1990-05-18 Elf Aquitaine Procede perfectionne de preparation de l-carnitine.
FR2596756B1 (fr) * 1986-04-04 1988-07-22 Elf Aquitaine Procede de purification de la carnitine
FR2621325B1 (fr) * 1987-10-02 1990-03-30 Elf Aquitaine Procede perfectionne de preparation de l-carnitine
FR2623520B1 (fr) * 1987-11-23 1990-04-20 Sanofi Sa Procede enzymatique continu de preparation de la l-carnitine
JP3059735B2 (ja) * 1989-10-13 2000-07-04 旭化成工業株式会社 Ｌ―カルニチンデヒドロゲナーゼおよびその製造法
JPH0673478B2 (ja) * 1990-01-11 1994-09-21 旭化成工業株式会社 Ｌ―カルニチンの高感度測定法および測定用組成物
JP2850515B2 (ja) * 1990-09-25 1999-01-27 東洋紡績株式会社 グルコースデヒドロゲナーゼおよびその製造法
JP2684238B2 (ja) * 1990-10-09 1997-12-03 旭化成工業株式会社 アシルカルニチンエステラーゼ及びその製造法
US5316917A (en) * 1992-11-04 1994-05-31 Duke University Automated analysis of free l-carnitine and total short-chain acylcarnitine
US5807926A (en) * 1996-10-11 1998-09-15 Mcgill University Immobilized cofactor-dependent enzymes
US6599723B1 (en) * 1999-03-11 2003-07-29 Eastman Chemical Company Enzymatic reductions with dihydrogen via metal catalyzed cofactor regeneration
US20030162241A1 (en) * 2000-04-17 2003-08-28 Fritz Pittner Method for determining the concentration of carnitine in fluids
US7407778B2 (en) 2002-02-07 2008-08-05 Pettegrew Jay W Compounds, compositions and methods for treating neuropsychiatric disorders
US7700074B2 (en) * 2002-02-07 2010-04-20 Pettegrew Jay W Method and system for diagnosis of neuropsychiatric disorders including chronic alcoholism
US20060257842A1 (en) * 2003-05-29 2006-11-16 Pettegrew Jay W Cryopreservation media and molecules
DE602004022301D1 (de) * 2003-05-29 2009-09-10 Jay W Pettegrew Glycerophosphocholin und derivate davon zur medizinischen abbildung von neuropsychiatrischen erkrankungen
KR100713103B1 (ko) * 2005-07-07 2007-05-02 씨제이 주식회사 뉴로스포라 크라사 유래 ｌ-카르니틴 생합성 관련 유전자를포함하는 엔테로박테리아세 속 미생물 및 이를 이용한ｌ-카르니틴의 제조방법
DE602005022120D1 (de) 2005-07-19 2010-08-12 Cj Cheiljedang Corp Mikroorganismus der gattung enterobacteriacae mit genen in zusammenhang mit der biosynthese von l-carnitin sowie verfahren zur produktion von l-carnitin mit dem mikroorganismus
CN101903528A (zh) * 2007-12-10 2010-12-01 巴斯夫欧洲公司 使用烯醇还原酶酶促还原α-和β-脱氢氨基酸的方法
CN104030934B (zh) * 2014-07-04 2016-06-15 东北制药集团股份有限公司 一种左卡尼汀化合物的制备方法

Also Published As

Publication number Publication date
US4221869A (en) 1980-09-09
FR2398046B1 (es) 1980-01-04
FR2398046A1 (fr) 1979-02-16
IT1097009B (it) 1985-08-26
IT7825551A0 (it) 1978-07-11
CH634878A5 (fr) 1983-02-28

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