ES468447A1 - Metodo de preparacion de pirido (2,1-b) quinazolin-onas. - Google Patents

Metodo de preparacion de pirido (2,1-b) quinazolin-onas.

Info

Publication number
ES468447A1
ES468447A1 ES468447A ES468447A ES468447A1 ES 468447 A1 ES468447 A1 ES 468447A1 ES 468447 A ES468447 A ES 468447A ES 468447 A ES468447 A ES 468447A ES 468447 A1 ES468447 A1 ES 468447A1
Authority
ES
Spain
Prior art keywords
quinazolin
pyrido
preparation
methods
ones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES468447A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Publication of ES468447A1 publication Critical patent/ES468447A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Método de preparación Pirido [2, 1-b] quinazolín-onas, que responden a la fórmula general: **(Fórmula)** en la que se selecciona R1-R4 a partir del grupo consistente en hidrógeno, halógeno, ciano, alcoxi, alquilo, alquenilo, aminoalcoxi, hidroxialcoxi, hidroxi, aralquiloxi, trifluorometilo, nitro, amino, monoalquilamino, dialquilamino, aralquilamino, acilamino, sulfonilamino, carboxi, carboalcoxi, carboxamido, carboxamido N-sustituido, metilsulfinilo, metilsulfonilo, arilsulfinilo, arilsufonilo, sulfonamido, ácido sulfónico, ciano, ácido acrílico, ácido oxiacético, tetrazolilo, N-(tetrazolil)-carboxamido y tetrazoliletileno, o mezclas de los mismos; R5 es seleccionado de un grupo consistente en hidrógeno, hidroxi, hidroxialquilo, hidroxialcoxi, carboxi, carboalcoxi, carboxamido y carboxamido N-sustituido, tetrazolilo, N-tetrazolilocarboxamido, tetrazoliletileno, sulfonamido y ácido sulfónico, ácido acrílico, ciano, ácido oxiacético y oximetiltetrazolilo que aparece opcionalmente en las posiciones 6-9 del anillo pirido; y R6 es seleccionado de un grupo consistente en hidrógeno, hidrófilo, alcoxi y radicales alquilo.
ES468447A 1975-10-07 1978-03-31 Metodo de preparacion de pirido (2,1-b) quinazolin-onas. Expired ES468447A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/620,471 US4033961A (en) 1975-10-07 1975-10-07 Pyrido[2-1-b]quinazolin-ones and their methods of preparation

Publications (1)

Publication Number Publication Date
ES468447A1 true ES468447A1 (es) 1978-12-16

Family

ID=24486085

Family Applications (3)

Application Number Title Priority Date Filing Date
ES452441A Expired ES452441A1 (es) 1975-10-07 1976-10-15 Metodo de preparacion de pirido (2,1-b) quinazolin-onas.
ES468448A Expired ES468448A1 (es) 1975-10-07 1978-03-31 Metodo de preparacion de pirido (2,1-b) quinazolin-onas.
ES468447A Expired ES468447A1 (es) 1975-10-07 1978-03-31 Metodo de preparacion de pirido (2,1-b) quinazolin-onas.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES452441A Expired ES452441A1 (es) 1975-10-07 1976-10-15 Metodo de preparacion de pirido (2,1-b) quinazolin-onas.
ES468448A Expired ES468448A1 (es) 1975-10-07 1978-03-31 Metodo de preparacion de pirido (2,1-b) quinazolin-onas.

Country Status (15)

Country Link
US (2) US4033961A (es)
JP (1) JPS5246099A (es)
AU (1) AU500196B2 (es)
BE (1) BE847011A (es)
CA (1) CA1197843A (es)
CH (1) CH605954A5 (es)
DE (1) DE2645110C2 (es)
DK (1) DK450776A (es)
ES (3) ES452441A1 (es)
FR (1) FR2326924A1 (es)
GB (1) GB1512299A (es)
IE (1) IE46232B1 (es)
LU (1) LU75943A1 (es)
NL (1) NL7611126A (es)
SE (1) SE434398B (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2557425C2 (de) * 1975-12-19 1987-03-19 C.H. Boehringer Sohn, 6507 Ingelheim 11-Oxo-11-H-pyrido[2,1-b]-chinazolin-2-carbonsäure und ihre Salze, Verfahren zu ihrer Herstellung und Arzneimittel
US4066767A (en) * 1976-11-01 1978-01-03 Warner-Lambert Company 8-(1H-Tetrazol-5-yl)-11H-pyrido[2,1-b]quinazolin-11-ones and method of treating bronchial asthma using them
DE2720085A1 (de) * 1977-05-05 1978-11-16 Hoechst Ag Pyrimido(6,1-a)isochinolin-2-on- derivate
DE2812585A1 (de) * 1977-03-24 1978-09-28 Hoffmann La Roche Chinazolin-derivate
HU182009B (en) * 1977-08-19 1983-12-28 Chinoin Gyogyszer Es Vegyeszet Process for producing substituted pirido-square bracket-1,2-a-square bracket closed-pyrimidines, pyrrolo-square bracket-1,2-a-square bracket closed-pyrimidines
DE2739020A1 (de) 1977-08-26 1979-03-01 Schering Ag Pyrido eckige klammer auf 2,1-b eckige klammer zu -chinazolinon-derivate, ihre herstellung und verwendung
US4127720A (en) * 1977-09-21 1978-11-28 Bristol-Myers Company Pyrimido[2,1-a]isoquinoline derivatives having antiallergy activity
US4348396A (en) * 1978-01-23 1982-09-07 Hoffmann-La Roche Inc. Substituted 11-oxo-11H-pyrido[2,1-b]quinazolines and method of inhibiting allergic reactions with them
US4491587A (en) * 1978-05-05 1985-01-01 Mead Johnson & Company Tetrazole derivatives
US4223031A (en) * 1978-05-05 1980-09-16 Mead Johnson & Company Azolopyrimidinones
DE2845766A1 (de) * 1978-10-18 1980-04-30 Schering Ag Pyrido eckige klammer auf 2,1-b eckige klammer zu -chinazolinon-derivate, ihre herstellung und verwendung
US4261996A (en) * 1980-01-11 1981-04-14 Warner-Lambert Company Pyrazolo[5,1-b]quinazolin-9-(4H)-ones and anti-allergic pharmaceutical compositions containing them
US4247555A (en) * 1980-01-11 1981-01-27 Warner-Lambert Company 4,9-Dihydro-9-oxo-N-1H-tetrazol-5-yl-pyrazolo[5,1-b]-quinazoline-2-carboxamides and antiallergic compositions and methods using them
US4261997A (en) * 1980-01-11 1981-04-14 Warner-Lambert Company 4-Alkyl-pyrazolo[5,1-b]-quinazolin-9(4H)-ones and anti-allergic compositions containing them
JPS55134807A (en) * 1979-04-06 1980-10-21 Hitachi Ltd Production of color filter
JPS55138839A (en) * 1979-04-17 1980-10-30 Nec Kyushu Ltd Method of fabricating semiconductor device
JPS574012A (en) * 1980-06-09 1982-01-09 Canon Inc Production of color filter
JPS587608A (ja) * 1981-07-08 1983-01-17 Hitachi Ltd カラ−フイルタの製造方法
US4395549A (en) 1981-10-02 1983-07-26 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. 6-Hydrazono-pyrido[2,1-b] quinazoline-11 ones
ES8406476A1 (es) * 1982-04-29 1984-07-01 Erba Farmitalia Procedimiento para preparar derivados cicloalifaticos condensados de pirido(1,2-a)pirimidinas sustituidas.
US4551460A (en) * 1982-05-10 1985-11-05 Hoffmann-La Roche Inc. Pyrido[2,1-b]quinazoline derivatives useful as agents for treatment of allergic conditions and vascular disorders involving thrombosis
ES8501397A1 (es) * 1982-08-05 1984-11-16 Erba Farmitalia "procedimiento para preparar derivados de quinazolina"
JPS5950411A (ja) * 1982-09-17 1984-03-23 Matsushita Electric Ind Co Ltd 色フイルタの製造方法
FR2533567A1 (fr) * 1982-09-23 1984-03-30 Ki I Farmakologii 2-(orthocarboxyphenylamino)-6h-pyrimido (2,1-b)-quinazolone-6 et ses derives, leur procede de preparation et leur application therapeutique
DE3300477A1 (de) * 1983-01-08 1984-07-12 Boehringer Ingelheim KG, 6507 Ingelheim Neue heterocyclische verbindungen, ihre herstellung und verwendung
GB8331228D0 (en) * 1983-11-23 1983-12-29 Fujisawa Pharmaceutical Co Pyrimidoisoquinoline derivatives
US5908840A (en) * 1996-11-26 1999-06-01 American Cyanamid Company Hetero-biaryl-pyridoquinazolinone derivatives as anti-cancer agents
US5914327A (en) * 1996-11-26 1999-06-22 American Cyanamid Company Biaryl-pyridoquinazolinone derivatives as anti-cancer agents
JP2018019062A (ja) * 2016-07-27 2018-02-01 サムソン エレクトロ−メカニックス カンパニーリミテッド． インダクタ

Also Published As

Publication number Publication date
US4104389A (en) 1978-08-01
JPS5526144B2 (es) 1980-07-11
ES468448A1 (es) 1978-12-16
GB1512299A (en) 1978-06-01
FR2326924A1 (fr) 1977-05-06
IE46232B1 (en) 1983-04-06
DE2645110C2 (de) 1982-11-18
CA1197843A (en) 1985-12-10
FR2326924B1 (es) 1980-07-04
CH605954A5 (es) 1978-10-13
DK450776A (da) 1977-04-08
ES452441A1 (es) 1978-08-16
AU1842076A (en) 1978-04-13
US4033961A (en) 1977-07-05
JPS5246099A (en) 1977-04-12
BE847011A (fr) 1977-04-06
NL7611126A (nl) 1977-04-13
AU500196B2 (en) 1979-05-10
IE46232L (en) 1977-04-07
SE7611169L (sv) 1977-04-08
LU75943A1 (es) 1977-05-06
SE434398B (sv) 1984-07-23
DE2645110A1 (de) 1977-04-21

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