ES463484A1 - Un procedimiento de preparacion de derivados del acido aci- lamino-clavulanico. - Google Patents

Un procedimiento de preparacion de derivados del acido aci- lamino-clavulanico.

Info

Publication number
ES463484A1
ES463484A1 ES463484A ES463484A ES463484A1 ES 463484 A1 ES463484 A1 ES 463484A1 ES 463484 A ES463484 A ES 463484A ES 463484 A ES463484 A ES 463484A ES 463484 A1 ES463484 A1 ES 463484A1
Authority
ES
Spain
Prior art keywords
clavam
beta
positive
negative bacteria
antibiotics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES463484A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB44145/76A external-priority patent/GB1594934A/en
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Publication of ES463484A1 publication Critical patent/ES463484A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

Un procedimiento de preparación de derivados del ácido acilamino-clavulánico de la fórmula (I) ***(ver fórmula) donde R es un grupo monoacilamino o un grupo diacilamino cíclico, cuyos grupos acilo están unidos formando con el átomo de nitrógeno un anillo heterocíclico, y R1 es un grupo carboxilo o carboxilo esterificado, y las formas de sal de los mismos, que comprenden hacer reaccionar un compuesto de fórmula (I) en donde R es un grupo -NH2 con un agente acilante.
ES463484A 1976-10-25 1977-10-24 Un procedimiento de preparacion de derivados del acido aci- lamino-clavulanico. Expired ES463484A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB44145/76A GB1594934A (en) 1976-10-25 1976-10-25 Clavulanic acid derivatives
GB2267977 1977-05-30

Publications (1)

Publication Number Publication Date
ES463484A1 true ES463484A1 (es) 1978-11-16

Family

ID=26256057

Family Applications (1)

Application Number Title Priority Date Filing Date
ES463484A Expired ES463484A1 (es) 1976-10-25 1977-10-24 Un procedimiento de preparacion de derivados del acido aci- lamino-clavulanico.

Country Status (12)

Country Link
JP (1) JPS53116395A (es)
AT (1) AT363181B (es)
AU (1) AU517920B2 (es)
DE (1) DE2747599A1 (es)
DK (1) DK471577A (es)
ES (1) ES463484A1 (es)
FI (1) FI773157A (es)
FR (1) FR2368490A1 (es)
IT (1) IT1091113B (es)
NL (1) NL7711640A (es)
NZ (1) NZ185511A (es)
SE (1) SE7711961L (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK330880A (da) * 1979-08-03 1981-02-04 Beecham Group Ltd Fremgangsmaade til fremstilling af clavulansyrederivater
US4343807A (en) 1979-09-27 1982-08-10 Beecham Group Limited Derivatives of clavulanic acid, a process for their preparation and their use
ZA805850B (en) 1979-09-27 1981-09-30 Beecham Group Ltd Derivatives of clavulanic acid, a process for their preparation and their use
EP0068609A1 (en) * 1981-06-11 1983-01-05 Beecham Group Plc Derivatives of clavulanic acid, a process for their preparation and their use
EP0068617A1 (en) * 1981-06-12 1983-01-05 Beecham Group Plc Derivatives of clavulanic acid, a process for their preparation and their use
GB8521516D0 (en) * 1985-08-29 1985-10-02 Beecham Group Plc Compounds

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1529434A (en) * 1974-10-22 1978-10-18 Beecham Group Ltd Acyl derivatives of clavulanic acid methods for their preparation and compositions containing them
GB1501643A (en) * 1974-10-28 1978-02-22 Beecham Group Ltd Antibacterial substituted azetidinones
IE42370B1 (en) * 1974-12-18 1980-07-30 Beecham Group Ltd Isoclavulanic acid derivatives
PT64897B (en) * 1975-04-14 1977-08-18 Beecham Group Ltd Process for the preparation of novel antibacterial agents
GB1542405A (en) * 1975-04-15 1979-03-21 Beecham Group Ltd Clavulanic acid derivatives
GB1493197A (en) * 1975-07-04 1977-11-23 Beecham Group Ltd Amides of clavulanic acid
IL50080A (en) * 1975-07-29 1979-07-25 Beecham Group Ltd 4-oxa-1-azabicyclo(3.2.0)heptan-7-one-2-car boxylic acid derivatives and their preparation
AU503489B2 (en) * 1975-10-13 1979-09-06 Beecham Group Limited Substituted aminodeoxy clavulanic acid
GB1547169A (en) * 1975-10-13 1979-06-06 Beecham Group Ltd Clavulanic acid derivatives
GB1504426A (en) * 1975-10-13 1978-03-22 Beecham Group Ltd Clavulanic acid derivatives

Also Published As

Publication number Publication date
SE7711961L (sv) 1978-06-15
FR2368490B1 (es) 1981-02-06
FR2368490A1 (fr) 1978-05-19
IT1091113B (it) 1985-06-26
DE2747599A1 (de) 1978-04-27
DK471577A (da) 1978-04-26
FI773157A (fi) 1978-04-26
JPS53116395A (en) 1978-10-11
NZ185511A (en) 1980-12-19
AU3002177A (en) 1979-06-07
AT363181B (de) 1981-07-10
ATA758877A (de) 1980-12-15
NL7711640A (nl) 1978-04-27
AU517920B2 (en) 1981-09-03

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