DK330880A - Fremgangsmaade til fremstilling af clavulansyrederivater - Google Patents

Fremgangsmaade til fremstilling af clavulansyrederivater

Info

Publication number
DK330880A
DK330880A DK330880A DK330880A DK330880A DK 330880 A DK330880 A DK 330880A DK 330880 A DK330880 A DK 330880A DK 330880 A DK330880 A DK 330880A DK 330880 A DK330880 A DK 330880A
Authority
DK
Denmark
Prior art keywords
group
alkyl
optionally substituted
preparation
procedure
Prior art date
Application number
DK330880A
Other languages
English (en)
Inventor
J B Harbridge
I Stirling
B P Clarke
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of DK330880A publication Critical patent/DK330880A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
DK330880A 1979-08-03 1980-07-31 Fremgangsmaade til fremstilling af clavulansyrederivater DK330880A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7927236 1979-08-03

Publications (1)

Publication Number Publication Date
DK330880A true DK330880A (da) 1981-02-04

Family

ID=10506994

Family Applications (1)

Application Number Title Priority Date Filing Date
DK330880A DK330880A (da) 1979-08-03 1980-07-31 Fremgangsmaade til fremstilling af clavulansyrederivater

Country Status (13)

Country Link
US (1) US4652560A (da)
EP (1) EP0025271B1 (da)
JP (1) JPS5649386A (da)
AT (1) ATE6652T1 (da)
AU (1) AU535481B2 (da)
CA (1) CA1170658A (da)
DE (1) DE3066974D1 (da)
DK (1) DK330880A (da)
ES (3) ES8105324A1 (da)
IE (1) IE50040B1 (da)
MY (1) MY8500998A (da)
NZ (1) NZ194535A (da)
ZA (1) ZA804670B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA804670B (en) * 1979-08-03 1981-07-29 Beecham Group Ltd Derivatives of clavulanic acid, a process for their preparation and their use
JPS58109455A (ja) * 1981-11-20 1983-06-29 Kureha Chem Ind Co Ltd Ｎ−ベンジルアミノ酸誘導体及びその製造法
EP0101199A1 (en) * 1982-07-22 1984-02-22 Beecham Group Plc Beta-lactam compounds
GB8521516D0 (en) * 1985-08-29 1985-10-02 Beecham Group Plc Compounds
GB0001833D0 (en) * 2000-01-26 2000-03-22 Isis Innovation Clavams

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR205682A1 (es) * 1970-06-11 1976-05-31 Philips Nv Metodo de produccion de ester (2-dimetilaminoetil) de acido (4-cloro-alfa - metilbenciliden) amino-oxiacetico y sus sales de adicion de acido formadas con acidos farmacologicamente aceptables
US4399142A (en) * 1973-05-03 1983-08-16 Smith Kline & French Laboratories Limited Pharmacologically active compounds
IE41109B1 (en) * 1974-04-20 1979-10-24 Beecham Group Ltd Novel -lactam antibiotic from streptomyces clavuligerus
AU503489B2 (en) * 1975-10-13 1979-09-06 Beecham Group Limited Substituted aminodeoxy clavulanic acid
GB1561290A (en) * 1975-10-16 1980-02-20 Nyegaard & Co As Pyrimid - 2 - ones
GB1515241A (en) * 1976-01-27 1978-06-21 Beecham Group Ltd Beta-lactam antibiotics
IL51267A (en) * 1976-01-31 1979-12-30 Beecham Group Ltd Clavulanic acid thioethers their preparation and pharmaceutical compositions containing them
BE858858A (fr) * 1976-10-16 1978-03-20 Fisons Ltd Composition de cromoglycate disodique
AT363181B (de) * 1976-10-25 1981-07-10 Glaxo Lab Ltd Verfahren zur herstellung von neuen clavulansaeurederivaten
GB1604822A (en) * 1977-04-22 1981-12-16 Beecham Group Ltd N-monosubstituted-9-amino-9-deoxyclavulanic acid derivative
GB1599907A (en) * 1977-04-26 1981-10-07 Glaxo Lab Ltd Isoindolines
EP0007152A1 (en) * 1978-04-28 1980-01-23 Beecham Group Plc Beta-lactam antibiotics, preparation and use
US4446146A (en) * 1978-07-26 1984-05-01 Beecham Group Limited β-Lactam containing compounds, their preparation and use
EP0007753B1 (en) * 1978-08-02 1982-08-25 Beecham Group Plc Beta-lactam antibacterial agents, a process for their preparation and pharmaceutical compositions containing them
DE2966065D1 (en) * 1978-09-09 1983-09-22 Beecham Group Plc Derivatives of clavulanic acid, a process for their preparation and their compositions
DE2966349D1 (en) * 1978-09-09 1983-12-01 Beecham Group Plc Derivatives of clavulanic acid, a process for their preparation and their use
US4405596A (en) * 1978-10-16 1983-09-20 Helbig Joachim W Pharmaceutical preparations for and treatment procedures involving increasing plasma bicarbonate level
DE2849646A1 (de) * 1978-11-16 1980-06-04 Hoechst Ag Thienylbenzoesaeurederivate und verfahren zu ihrer herstellung
EP0021840B1 (en) * 1979-06-29 1983-08-31 Glaxo Group Limited Heterocyclic compounds, processes for their preparation and compositions containing them
FI75578C (fi) * 1979-07-25 1988-07-11 Ciba Geigy Ag Analogifoerfarande foer framstaellning av farmakologiskt verkande lipofila fosfatidylmuramylpeptider.
ZA804670B (en) * 1979-08-03 1981-07-29 Beecham Group Ltd Derivatives of clavulanic acid, a process for their preparation and their use
US4315006A (en) * 1979-08-09 1982-02-09 Glaxo Group Limited Benzoxocin derivatives having anxiolytic and anti-convulsant activities
US4402949A (en) * 1979-11-12 1983-09-06 Sandoz Ltd. Stable solutions of hydrogenated ergotalkaloids
US4315935A (en) * 1980-04-14 1982-02-16 Smithkline Corporation N,N'-Bis[substituted-1,2,3,4-tetrahydroisoquinolinolyl]disulfonylimides and antiallergic compositions and method of use
US4317826A (en) * 1980-05-27 1982-03-02 Smithkline Corporation N,N'-Bis[substituted-1,2,3,4 tetrahydroisoquinolyl]disulfonylimides and antiallergic compositions and method of use
IT1150955B (it) * 1980-06-06 1986-12-17 Lepetit Spa Derivati 3h-naft(1.2-d)-imidazolici il procedimento per la loro preparazione, il loro uso come agenti antiinfiammatori e le composizioni farmaceutiche che li contengono
EP0043197A1 (en) * 1980-07-02 1982-01-06 Beecham Group Plc Beta-Lactam antibiotic, its preparation and use
US4321254A (en) * 1980-09-26 1982-03-23 Smithkline Corporation Antiallergic imidodisulfamides
US4385047A (en) * 1981-01-05 1983-05-24 Smithkline Beckman Corporation Antiallergic imidodisulfamides
US4350685A (en) * 1981-02-06 1982-09-21 Smithkline Corporation Antiallergic imidodisulfamides
US4341786A (en) * 1981-03-02 1982-07-27 Smithkline Corporation Pharmaceutical compositions and method of producing central alpha1 agonist activity utilizing octahydrobenzo[f]quinoline compounds
FR2502153A1 (fr) * 1981-03-19 1982-09-24 Rech Pharmaceutiq Medicale Acides (2-oxo-3-tetrahydrothienylcarbamoyl)-alkylthio) acetiques, leurs sels et leurs esters, leur procede de preparation et les compositions pharmaceutiques en contenant
US4401665A (en) * 1981-04-14 1983-08-30 Bristol-Myers Company Sleep-aid composition containing an analgesic and diphenhydramine dihydrogencitrate, and method of use
US4402976A (en) * 1981-04-24 1983-09-06 E. R. Squibb & Sons, Inc. Method for treating glaucoma with systemic nadolol compositions
US4402974A (en) * 1981-06-23 1983-09-06 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
US4352809A (en) * 1981-09-04 1982-10-05 Smithkline Corporation Method of producing alpha2 antagonism
US4396620A (en) * 1981-09-08 1983-08-02 Eli Lilly And Company Cephalosporin quinolinium betaines
US4382932A (en) * 1981-09-08 1983-05-10 Eli Lilly And Company Isoquinolinium substituted cephalosporins
US4406898A (en) * 1981-09-08 1983-09-27 Eli Lilly And Company Oxazole and oxadiazole cephalosporins
US4396619A (en) * 1981-09-08 1983-08-02 Eli Lilly And Company Cephalosporin betaines
US4388316A (en) * 1981-10-02 1983-06-14 Eli Lilly And Company Amino-substituted oxazole, oxadiazole and isoxazole-substituted cephalosporins
US4402955A (en) * 1981-10-02 1983-09-06 Eli Lilly And Company Dioximino cephalosporin antibiotics
US4379787A (en) * 1981-10-02 1983-04-12 Eli Lilly And Company Oximino-substituted cephalosporin compounds
US4401668A (en) * 1981-10-02 1983-08-30 Eli Lilly And Company Pyrazinium substituted cephalosporins
US4406899A (en) * 1982-03-04 1983-09-27 Bristol-Myers Company Cephalosporins
US4397845A (en) * 1982-05-19 1983-08-09 The Upjohn Company Lincomycin 3-(5'-adenylate) as anesthetic
EP0101199A1 (en) * 1982-07-22 1984-02-22 Beecham Group Plc Beta-lactam compounds

Also Published As

Publication number Publication date
IE801613L (en) 1981-02-03
IE50040B1 (en) 1986-02-05
MY8500998A (en) 1985-12-31
AU535481B2 (en) 1984-03-22
ATE6652T1 (de) 1984-03-15
ES493944A0 (es) 1981-06-01
ES499944A0 (es) 1982-02-01
ES8105324A1 (es) 1981-06-01
ES8202014A1 (es) 1982-01-01
CA1170658A (en) 1984-07-10
EP0025271B1 (en) 1984-03-14
ZA804670B (en) 1981-07-29
ES499943A0 (es) 1982-01-01
US4652560A (en) 1987-03-24
EP0025271A1 (en) 1981-03-18
JPS5649386A (en) 1981-05-02
DE3066974D1 (en) 1984-04-19
AU6100980A (en) 1981-02-05
NZ194535A (en) 1984-09-28
ES8202556A1 (es) 1982-02-01

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