GB2006783A - Acylation of Lactone- substituted Aniline Compounds - Google Patents

Acylation of Lactone- substituted Aniline Compounds

Info

Publication number
GB2006783A
GB2006783A GB7842563A GB7842563A GB2006783A GB 2006783 A GB2006783 A GB 2006783A GB 7842563 A GB7842563 A GB 7842563A GB 7842563 A GB7842563 A GB 7842563A GB 2006783 A GB2006783 A GB 2006783A
Authority
GB
United Kingdom
Prior art keywords
substituted
acylation
lactone
substituted aniline
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7842563A
Other versions
GB2006783B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chevron USA Inc
Original Assignee
Chevron Research and Technology Co
Chevron Research Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chevron Research and Technology Co, Chevron Research Co filed Critical Chevron Research and Technology Co
Publication of GB2006783A publication Critical patent/GB2006783A/en
Application granted granted Critical
Publication of GB2006783B publication Critical patent/GB2006783B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/36—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A compound of the formula: <IMAGE> wherein Ar is a phenyl group which may be substituted by certain radicals, R<1> is alkyl, alkoxyalkyl or hydroxyalkyl (optionally substituted by halogen) or a phenyl or benzyl group which may be substituted by certain radicals, R<2> is hydrogen or a C1-4 alkyl group, R<3> is hydrogen a C1-4 alkyl group or a phenyl group which may be substituted by certain radicals and Y is -O- or -S-, is prepared by contacting, in the absence of an acid acceptor, an acyl halide of the general formula R'C=OX with an aniline substituted gamma-butyrolactone of the general formula: <IMAGE> in the presence of a non-basic organic solvent and at a temperature in the range from 50 to 200 DEG C.
GB7842563A 1977-11-01 1978-10-31 Acylation of lactone substituted aniline compounds Expired GB2006783B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US84750477A 1977-11-01 1977-11-01

Publications (2)

Publication Number Publication Date
GB2006783A true GB2006783A (en) 1979-05-10
GB2006783B GB2006783B (en) 1982-02-03

Family

ID=25300794

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7842563A Expired GB2006783B (en) 1977-11-01 1978-10-31 Acylation of lactone substituted aniline compounds

Country Status (7)

Country Link
JP (1) JPS5470260A (en)
BR (1) BR7807190A (en)
CH (1) CH639966A5 (en)
DE (1) DE2847075A1 (en)
FR (1) FR2408601A1 (en)
GB (1) GB2006783B (en)
IT (1) IT1100884B (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2469409A1 (en) * 1979-11-13 1981-05-22 Chevron Res PROCESS FOR THE PREPARATION OF A LACTONE-ANILINE
FR2491062A1 (en) * 1980-06-23 1982-04-02 Chevron Res 1-CARBOXY-1- (N-ARYL-N-ACYLAMINO) -3- (ALKYL, ALKENYL OR ARYLALKYL-THIO) -PROPANS POSSIBLY SUBSTITUTED, THEIR PREPARATION AND THEIR APPLICATION TO THE PREPARATION OF GAMMA-BUTYRO-THIO-LACTONS CORRESPONDING
US4721797A (en) * 1986-09-02 1988-01-26 Ciba-Geigy Corporation Process for the preparation of N-acyl-N-alkyl-2,6-dialkyl-3-chloroanilines
US4728669A (en) * 1977-11-01 1988-03-01 Chevron Research Company Fungicidal 3-(N-acyl-N-arylamino)-gamma-butyrolactones and gamma-butyrothiolactones

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH636093A5 (en) * 1978-01-28 1983-05-13 Ciba Geigy Ag MICROBICIDAL AGENTS.
EP0016985A1 (en) * 1979-03-16 1980-10-15 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Substituted anilides, processes for their preparation, fungicides containing such compounds, and use of such compounds or fungicides in combating plant fungi
DK13681A (en) * 1980-01-31 1981-08-01 Hoffmann La Roche SUBSTITUTED ANILIDES

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH587605A5 (en) * 1974-04-01 1977-05-13 Ciba Geigy Ag
US3933860A (en) * 1975-02-10 1976-01-20 Chevron Research Company 3-(N-acyl-N-arylamino) lactones
US4147792A (en) * 1977-02-04 1979-04-03 Ciba-Geigy Corporation Fungicidal compositions

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4728669A (en) * 1977-11-01 1988-03-01 Chevron Research Company Fungicidal 3-(N-acyl-N-arylamino)-gamma-butyrolactones and gamma-butyrothiolactones
FR2469409A1 (en) * 1979-11-13 1981-05-22 Chevron Res PROCESS FOR THE PREPARATION OF A LACTONE-ANILINE
FR2491062A1 (en) * 1980-06-23 1982-04-02 Chevron Res 1-CARBOXY-1- (N-ARYL-N-ACYLAMINO) -3- (ALKYL, ALKENYL OR ARYLALKYL-THIO) -PROPANS POSSIBLY SUBSTITUTED, THEIR PREPARATION AND THEIR APPLICATION TO THE PREPARATION OF GAMMA-BUTYRO-THIO-LACTONS CORRESPONDING
US4721797A (en) * 1986-09-02 1988-01-26 Ciba-Geigy Corporation Process for the preparation of N-acyl-N-alkyl-2,6-dialkyl-3-chloroanilines

Also Published As

Publication number Publication date
BR7807190A (en) 1979-06-12
DE2847075A1 (en) 1979-05-10
FR2408601B1 (en) 1983-08-12
JPS5470260A (en) 1979-06-05
GB2006783B (en) 1982-02-03
IT1100884B (en) 1985-09-28
IT7829299A0 (en) 1978-10-31
CH639966A5 (en) 1983-12-15
FR2408601A1 (en) 1979-06-08

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19971031