ES458264A1 - Procedimiento para la preparacion de nuevos compuestos ana- logos a prostaglandinas. - Google Patents
Procedimiento para la preparacion de nuevos compuestos ana- logos a prostaglandinas.Info
- Publication number
- ES458264A1 ES458264A1 ES458264A ES458264A ES458264A1 ES 458264 A1 ES458264 A1 ES 458264A1 ES 458264 A ES458264 A ES 458264A ES 458264 A ES458264 A ES 458264A ES 458264 A1 ES458264 A1 ES 458264A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- manufacutre
- pyrrolidones
- hydrocarbonate
- hydrocarbonate radical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19762619638 DE2619638A1 (de) | 1976-05-04 | 1976-05-04 | Pyrrolidone und verfahren zu ihrer herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
ES458264A1 true ES458264A1 (es) | 1978-07-16 |
Family
ID=5977020
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES458264A Expired ES458264A1 (es) | 1976-05-04 | 1977-04-28 | Procedimiento para la preparacion de nuevos compuestos ana- logos a prostaglandinas. |
Country Status (9)
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4320136A (en) | 1980-08-11 | 1982-03-16 | E. I. Du Pont De Nemours And Company | 8-Aza-16,16-difluoroprostanoids |
US4321201A (en) | 1980-09-22 | 1982-03-23 | E. I. Du Pont De Nemours And Company | Optically active tert-alkyl 7-(2-oxo-5-carbonyloxypyrrolidinyl) heptanoates |
JPH03500534A (ja) * | 1988-04-22 | 1991-02-07 | 2 モスコフスキ ゴスダルストベンニ メディツィンスキ インスティテュト イメニ エヌー.イー.ピロゴバ | ラクタム‐1‐酢酸カルボアルコキシメチルエステル及びその製造方法 |
CZ20022048A3 (cs) | 1999-12-22 | 2004-03-17 | Pfizer Products Inc. | Selektivní agonisty receptoru EP4 při léčení osteoporosy |
AU2001290250A1 (en) * | 2000-09-21 | 2002-04-02 | Ono Pharmaceutical Co. Ltd. | Ep4 receptor agonists containing 8-azaprostaglandin derivatives as the active ingredient |
CN1476429A (zh) | 2000-11-27 | 2004-02-18 | �Ʒ� | 治疗骨质疏松的ep4受体选择性激动剂 |
PL215425B1 (pl) | 2001-07-16 | 2013-12-31 | Ono Pharmaceutical Co | Pochodna pirolidonu, srodek farmaceutyczny zawierajacy te pochodna i jej zastosowanie |
MXPA04000456A (es) | 2001-07-16 | 2004-03-18 | Hoffmann La Roche | Analogos de prostaglandina como agonistas del receptor ep4. |
CN101921220B (zh) | 2001-07-23 | 2013-05-22 | 小野药品工业株式会社 | 治疗与骨质损失有关的疾病的含有ep4激动剂作为活性成分的药物组合物 |
JP4547912B2 (ja) | 2002-03-05 | 2010-09-22 | 小野薬品工業株式会社 | 8−アザプロスタグランジン誘導体化合物およびその化合物を有効成分として含有する薬剤 |
WO2003103604A2 (en) * | 2002-06-01 | 2003-12-18 | Applied Research Systems Ars Holding N.V | Gamma lactams as prostaglandin agonists and use thereof |
CN1735597A (zh) | 2003-01-10 | 2006-02-15 | 霍夫曼-拉罗奇有限公司 | 作为前列腺素激动剂的2-哌啶酮衍生物 |
WO2004065365A1 (ja) * | 2003-01-21 | 2004-08-05 | Ono Pharmaceutical Co., Ltd. | 8−アザプロスタグランジン誘導体およびその医薬用途 |
US7179820B2 (en) | 2003-06-06 | 2007-02-20 | Allergan, Inc. | Piperidinyl prostaglandin E analogs |
WO2006043655A1 (ja) * | 2004-10-22 | 2006-04-27 | Ono Pharmaceutical Co., Ltd. | 吸入用医薬組成物 |
PT2875022T (pt) | 2012-07-19 | 2016-12-22 | Cayman Chemical Co Inc | Compostos de difluorolactama como agonistas seletivos quanto ao recetor ep4 para uso no tratamento de doença e condições mediadas por ep4 |
DK2989098T3 (en) | 2013-03-15 | 2017-08-28 | Cayman Chemical Co Inc | LACTAM RELATIONS AS EP4 RECEPTOR SELECTIVE AGONISTS FOR USING THE TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS |
JP6368351B2 (ja) | 2013-03-15 | 2018-08-01 | ケイマン ケミカル カンパニー, インコーポレーテッド | ジフルオロラクタムアナログを合成する方法 |
WO2014144610A1 (en) * | 2013-03-15 | 2014-09-18 | Cayman Chemical Company, Inc. | Lactam compounds as ep4 receptor-selective agonists for use in the treatment of ep4-mediated diseases and conditions |
AU2014290512A1 (en) | 2013-07-19 | 2015-11-12 | Cayman Chemical Company, Inc. | Methods, systems, and compositions for promoting bone growth |
-
1976
- 1976-05-04 DE DE19762619638 patent/DE2619638A1/de active Pending
-
1977
- 1977-04-28 ES ES458264A patent/ES458264A1/es not_active Expired
- 1977-04-29 NL NL7704739A patent/NL7704739A/xx not_active Application Discontinuation
- 1977-05-02 IT IT23096/77A patent/IT1086223B/it active
- 1977-05-03 DK DK194377A patent/DK194377A/da unknown
- 1977-05-03 GB GB18427/77A patent/GB1583163A/en not_active Expired
- 1977-05-04 FR FR7713518A patent/FR2372806A1/fr active Granted
- 1977-05-04 JP JP5194577A patent/JPS52133975A/ja active Pending
- 1977-05-04 BE BE177278A patent/BE854268A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
JPS52133975A (en) | 1977-11-09 |
BE854268A (fr) | 1977-11-04 |
DK194377A (da) | 1977-11-05 |
GB1583163A (en) | 1981-01-21 |
DE2619638A1 (de) | 1977-11-17 |
NL7704739A (nl) | 1977-11-08 |
FR2372806B1 (US06811534-20041102-M00003.png) | 1980-02-29 |
IT1086223B (it) | 1985-05-28 |
FR2372806A1 (fr) | 1978-06-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES458264A1 (es) | Procedimiento para la preparacion de nuevos compuestos ana- logos a prostaglandinas. | |
ES458176A1 (es) | Procedimiento para la preparacion de derivados de indazolil-(4)-oxi-propanolamina. | |
ES462849A1 (es) | Un procedimiento para la preparacion de nuevos derivados de 3,5-diona-4,4-dimetil-pirrolidina. | |
ES476452A1 (es) | Un procedimiento para la produccion de una ciclohex-3-en-1- ona | |
ES445263A1 (es) | Un procedimiento para preparar un nuevo derivado de dimer- captoetileter. | |
ES445981A1 (es) | Procedimiento para la preparacion de un compuesto intermedioen la sintesis de 9 alfa-halogeno-16 beta-metil-prednisolo- na. | |
ES462437A1 (es) | Procedimiento para preparar nuevos 2,2-dimetil-19-nor-este- roides. | |
ES438725A1 (es) | Un procedimiento de preparacion de derivados sustituidos del acido prostanoico. | |
ES459871A1 (es) | Procedimiento para la obtencion de sales de hidrocarbil-tio-etilaminas. | |
ES433723A1 (es) | Procedimiento de obtencion de un derivado de 2-pirrolidi- nona. | |
ES458389A1 (es) | Procedimiento para preparar derivados de prostaglandina. | |
JPS5231448A (en) | Gripper | |
ES464851A1 (es) | Procedimiento para la preparacion de derivados de acidos 3- carboxifenilaceticos. | |
FR2407925B1 (US06811534-20041102-M00003.png) | ||
ES460297A1 (es) | Un compuesto. | |
JPS5246233A (en) | Carburetor | |
ES458806A1 (es) | Un procedimiento para preparar fenilalquilaminas. | |
ES478050A1 (es) | Procedimiento para la preparacion de 1-metil-isoguanosina. | |
ES452702A1 (es) | Un procedimiento para la preparacion de 2-alquilamino-1-(2- tiemil)-etanoles. | |
ES461324A1 (es) | Un procedimiento para la preparacion de d-homoesteroides. | |
ES459948A1 (es) | Un procedimiento para la preparacion de alfa-mecaptopropio- nilglicinato de arginina. | |
ES458835A1 (es) | Procedimiento para preparar 5-n-propilbencimidazolcarbamato de metilo. | |
ES460411A2 (es) | Procedimiento de preparacion de derivados arilamino-pirimi- dinicos. | |
JPS548642A (en) | Improvement in anticorrosion of electrodeposit coating film | |
JPS51121208A (en) | Pcm regenerative repeators |