ES456605A1 - Un procedimiento para la produccion de un compuesto de ami- dina sustituida. - Google Patents

Un procedimiento para la produccion de un compuesto de ami- dina sustituida.

Info

Publication number
ES456605A1
ES456605A1 ES456605A ES456605A ES456605A1 ES 456605 A1 ES456605 A1 ES 456605A1 ES 456605 A ES456605 A ES 456605A ES 456605 A ES456605 A ES 456605A ES 456605 A1 ES456605 A1 ES 456605A1
Authority
ES
Spain
Prior art keywords
reaction
disubstituted
naphthaleneacetamidines
naphthaleneacetamidine
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES456605A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dow Chemical Co
Original Assignee
Dow Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Chemical Co filed Critical Dow Chemical Co
Publication of ES456605A1 publication Critical patent/ES456605A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Un procedimiento para la producción de un compuesto de amidina sustituida correspondiente a la fórmula **(Fórmula)** donde R1 y R2 representan cada uno de ellos independientemente halógeno, alquilo C1-3 o alcoxi C1-3; m y n representan independientemente cada uno de ellos 0 ó 1 y R'' y R'''' representan independientemente cada uno de ellos alquilo C1-3, cuyo procedimiento consiste en hacer reaccionar un compuesto de naftalenacetonitrilo.
ES456605A 1974-10-02 1977-03-07 Un procedimiento para la produccion de un compuesto de ami- dina sustituida. Expired ES456605A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US510956A US3903163A (en) 1974-10-02 1974-10-02 N,N-Disubstituted naphthaleneacetamidines

Publications (1)

Publication Number Publication Date
ES456605A1 true ES456605A1 (es) 1978-01-16

Family

ID=24032883

Family Applications (1)

Application Number Title Priority Date Filing Date
ES456605A Expired ES456605A1 (es) 1974-10-02 1977-03-07 Un procedimiento para la produccion de un compuesto de ami- dina sustituida.

Country Status (14)

Country Link
US (1) US3903163A (es)
JP (1) JPS5817457B2 (es)
AR (1) AR211104A1 (es)
BE (1) BE834079A (es)
CA (1) CA1055960A (es)
CH (1) CH615153A5 (es)
DE (1) DE2542791C2 (es)
DK (2) DK154643C (es)
ES (1) ES456605A1 (es)
FR (1) FR2286644A1 (es)
GB (1) GB1463945A (es)
IE (1) IE42754B1 (es)
LU (1) LU73484A1 (es)
NL (1) NL184000C (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1121792B (it) * 1978-07-03 1986-04-23 Dow Chemical Co Un processo per preparare 2-naftalenetanimidamidi n,n'-di-sostituite e intermedi usati in questo processo
ATE182889T1 (de) * 1994-05-07 1999-08-15 Astra Ab Bicyclische amidinderivate als no-synthetase inhibitoren
US6025355A (en) * 1997-05-19 2000-02-15 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
US6242198B1 (en) 1996-07-25 2001-06-05 Cambridge Neuroscience, Inc. Methods of treatment of eye trauma and disorders
US6756389B2 (en) * 1996-08-09 2004-06-29 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use

Also Published As

Publication number Publication date
FR2286644B1 (es) 1980-05-16
AU8518775A (en) 1977-03-31
DK159266C (da) 1991-03-11
JPS5159844A (en) 1976-05-25
CH615153A5 (es) 1980-01-15
DK159266B (da) 1990-09-24
NL184000B (nl) 1988-10-17
DK289188A (da) 1988-05-26
IE42754B1 (en) 1980-10-08
DK154643C (da) 1989-05-08
FR2286644A1 (fr) 1976-04-30
GB1463945A (en) 1977-02-09
JPS5817457B2 (ja) 1983-04-07
BE834079A (fr) 1976-04-01
NL7511245A (nl) 1976-04-06
LU73484A1 (es) 1977-05-11
DK154643B (da) 1988-12-05
IE42754L (en) 1976-04-02
AR211104A1 (es) 1977-10-31
US3903163A (en) 1975-09-02
DK289188D0 (da) 1988-05-26
DK430475A (da) 1976-04-03
NL184000C (nl) 1989-03-16
DE2542791C2 (de) 1984-11-08
CA1055960A (en) 1979-06-05
DE2542791A1 (de) 1976-04-15

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