ES456605A1 - Un procedimiento para la produccion de un compuesto de ami- dina sustituida. - Google Patents
Un procedimiento para la produccion de un compuesto de ami- dina sustituida.Info
- Publication number
- ES456605A1 ES456605A1 ES456605A ES456605A ES456605A1 ES 456605 A1 ES456605 A1 ES 456605A1 ES 456605 A ES456605 A ES 456605A ES 456605 A ES456605 A ES 456605A ES 456605 A1 ES456605 A1 ES 456605A1
- Authority
- ES
- Spain
- Prior art keywords
- reaction
- disubstituted
- naphthaleneacetamidines
- naphthaleneacetamidine
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 N,N-Disubstituted naphthaleneacetamidines Chemical class 0.000 title abstract 2
- 150000003973 alkyl amines Chemical class 0.000 abstract 2
- LPCWDVLDJVZIHA-UHFFFAOYSA-N 2-naphthalen-2-ylacetonitrile Chemical class C1=CC=CC2=CC(CC#N)=CC=C21 LPCWDVLDJVZIHA-UHFFFAOYSA-N 0.000 abstract 1
- 125000005210 alkyl ammonium group Chemical group 0.000 abstract 1
- 230000000049 anti-anxiety effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 239000002249 anxiolytic agent Substances 0.000 abstract 1
- 230000001914 calming effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- NAHCWQNNENHGNH-UHFFFAOYSA-N n,n'-dimethyl-2-naphthalen-2-ylethanimidamide Chemical compound C1=CC=CC2=CC(CC(NC)=NC)=CC=C21 NAHCWQNNENHGNH-UHFFFAOYSA-N 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
- C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US510956A US3903163A (en) | 1974-10-02 | 1974-10-02 | N,N-Disubstituted naphthaleneacetamidines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES456605A1 true ES456605A1 (es) | 1978-01-16 |
Family
ID=24032883
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES456605A Expired ES456605A1 (es) | 1974-10-02 | 1977-03-07 | Un procedimiento para la produccion de un compuesto de ami- dina sustituida. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US3903163A (en, 2012) |
| JP (1) | JPS5817457B2 (en, 2012) |
| AR (1) | AR211104A1 (en, 2012) |
| BE (1) | BE834079A (en, 2012) |
| CA (1) | CA1055960A (en, 2012) |
| CH (1) | CH615153A5 (en, 2012) |
| DE (1) | DE2542791C2 (en, 2012) |
| DK (2) | DK154643C (en, 2012) |
| ES (1) | ES456605A1 (en, 2012) |
| FR (1) | FR2286644A1 (en, 2012) |
| GB (1) | GB1463945A (en, 2012) |
| IE (1) | IE42754B1 (en, 2012) |
| LU (1) | LU73484A1 (en, 2012) |
| NL (1) | NL184000C (en, 2012) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1121792B (it) * | 1978-07-03 | 1986-04-23 | Dow Chemical Co | Un processo per preparare 2-naftalenetanimidamidi n,n'-di-sostituite e intermedi usati in questo processo |
| CA2188680A1 (en) * | 1994-05-07 | 1996-01-25 | James Edwin Macdonald | Bicyclic amidine derivatives as inhibitors of nitric oxide synthetase |
| US6025355A (en) | 1997-05-19 | 2000-02-15 | Cambridge Neuroscience, Inc. | Pharmaceutically active compounds and methods of use |
| US6242198B1 (en) | 1996-07-25 | 2001-06-05 | Cambridge Neuroscience, Inc. | Methods of treatment of eye trauma and disorders |
| US6756389B2 (en) * | 1996-08-09 | 2004-06-29 | Cambridge Neuroscience, Inc. | Pharmaceutically active compounds and methods of use |
-
1974
- 1974-10-02 US US510956A patent/US3903163A/en not_active Expired - Lifetime
-
1975
- 1975-09-24 NL NLAANVRAGE7511245,A patent/NL184000C/xx not_active IP Right Cessation
- 1975-09-25 DE DE2542791A patent/DE2542791C2/de not_active Expired
- 1975-09-25 DK DK430475A patent/DK154643C/da not_active IP Right Cessation
- 1975-09-25 CA CA236,376A patent/CA1055960A/en not_active Expired
- 1975-09-26 FR FR7529528A patent/FR2286644A1/fr active Granted
- 1975-09-26 GB GB3959975A patent/GB1463945A/en not_active Expired
- 1975-09-29 AR AR260600A patent/AR211104A1/es active
- 1975-09-30 IE IE2140/75A patent/IE42754B1/en not_active IP Right Cessation
- 1975-09-30 LU LU73484A patent/LU73484A1/xx unknown
- 1975-09-30 JP JP50118188A patent/JPS5817457B2/ja not_active Expired
- 1975-10-01 BE BE160595A patent/BE834079A/xx not_active IP Right Cessation
- 1975-10-02 CH CH1281275A patent/CH615153A5/de not_active IP Right Cessation
-
1977
- 1977-03-07 ES ES456605A patent/ES456605A1/es not_active Expired
-
1988
- 1988-05-26 DK DK289188A patent/DK159266C/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NL184000C (nl) | 1989-03-16 |
| DK289188D0 (da) | 1988-05-26 |
| BE834079A (fr) | 1976-04-01 |
| CA1055960A (en) | 1979-06-05 |
| IE42754L (en) | 1976-04-02 |
| DK289188A (da) | 1988-05-26 |
| IE42754B1 (en) | 1980-10-08 |
| AR211104A1 (es) | 1977-10-31 |
| NL7511245A (nl) | 1976-04-06 |
| AU8518775A (en) | 1977-03-31 |
| DK154643B (da) | 1988-12-05 |
| GB1463945A (en) | 1977-02-09 |
| DK154643C (da) | 1989-05-08 |
| DE2542791C2 (de) | 1984-11-08 |
| JPS5817457B2 (ja) | 1983-04-07 |
| CH615153A5 (en, 2012) | 1980-01-15 |
| DK159266C (da) | 1991-03-11 |
| FR2286644B1 (en, 2012) | 1980-05-16 |
| FR2286644A1 (fr) | 1976-04-30 |
| JPS5159844A (en) | 1976-05-25 |
| DK159266B (da) | 1990-09-24 |
| LU73484A1 (en, 2012) | 1977-05-11 |
| DK430475A (da) | 1976-04-03 |
| DE2542791A1 (de) | 1976-04-15 |
| NL184000B (nl) | 1988-10-17 |
| US3903163A (en) | 1975-09-02 |
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