ES453508A1 - Un procedimiento para la preparacion de nuevas sustancias antibioticas desacetil-89oa1 y desacetil-89oa2. - Google Patents
Un procedimiento para la preparacion de nuevas sustancias antibioticas desacetil-89oa1 y desacetil-89oa2.Info
- Publication number
- ES453508A1 ES453508A1 ES453508A ES453508A ES453508A1 ES 453508 A1 ES453508 A1 ES 453508A1 ES 453508 A ES453508 A ES 453508A ES 453508 A ES453508 A ES 453508A ES 453508 A1 ES453508 A1 ES 453508A1
- Authority
- ES
- Spain
- Prior art keywords
- antibiatics
- desacetyl
- deacetyl
- thienamycin
- antibiotics
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
- C12P17/184—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system containing a beta-lactam ring, e.g. thienamycin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63456075A | 1975-11-24 | 1975-11-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES453508A1 true ES453508A1 (es) | 1978-03-01 |
Family
ID=24544292
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES453508A Expired ES453508A1 (es) | 1975-11-24 | 1976-11-19 | Un procedimiento para la preparacion de nuevas sustancias antibioticas desacetil-89oa1 y desacetil-89oa2. |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPS5265295A (enExample) |
| AR (1) | AR224224A1 (enExample) |
| AU (1) | AU510252B2 (enExample) |
| BE (1) | BE848349A (enExample) |
| CH (1) | CH625803A5 (enExample) |
| DE (1) | DE2652678A1 (enExample) |
| DK (1) | DK497476A (enExample) |
| ES (1) | ES453508A1 (enExample) |
| FR (1) | FR2351979A1 (enExample) |
| GB (1) | GB1561108A (enExample) |
| GR (1) | GR61407B (enExample) |
| HU (1) | HU175266B (enExample) |
| NL (1) | NL7612932A (enExample) |
| PT (1) | PT65845B (enExample) |
| SE (1) | SE7612295L (enExample) |
| ZA (1) | ZA766986B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7800958A (nl) * | 1977-02-11 | 1978-08-15 | Merck & Co Inc | Antibioticum desacetyl-dihydro 890 a9, werkwijze ter bereiding daarvan en farmaceutisch preparaat dat dit antibioticum bevat. |
| SE7800978L (sv) * | 1977-02-11 | 1978-08-12 | Merck & Co Inc | Antibiotikum |
| US4162193A (en) * | 1977-08-19 | 1979-07-24 | Merck & Co., Inc. | Enzymatic cleavage of N-acyl-thienamycins |
| NZ190994A (en) | 1978-07-24 | 1981-10-19 | Merck & Co Inc | Z-2-acylamino-3-monosubstituted propenoates |
| DE2965923D1 (en) * | 1979-08-28 | 1983-08-25 | Merck & Co Inc | Process for purifying thienamycin |
| DE3146190A1 (de) * | 1981-11-21 | 1983-06-16 | Hoechst Ag, 6230 Frankfurt | Isolierung von chemisch instabilen antibiotika aus fermentationsloesungen |
| WO2017132321A1 (en) * | 2016-01-29 | 2017-08-03 | The Johns Hopkins University | Novel inhibitors of bacterial growth |
-
1976
- 1976-11-03 DK DK497476A patent/DK497476A/da not_active Application Discontinuation
- 1976-11-04 SE SE7612295A patent/SE7612295L/xx not_active Application Discontinuation
- 1976-11-15 AU AU19645/76A patent/AU510252B2/en not_active Expired
- 1976-11-16 PT PT65845A patent/PT65845B/pt unknown
- 1976-11-16 BE BE172363A patent/BE848349A/xx not_active IP Right Cessation
- 1976-11-16 AR AR265526A patent/AR224224A1/es active
- 1976-11-18 HU HUME002031 patent/HU175266B/hu unknown
- 1976-11-19 GB GB48233/76A patent/GB1561108A/en not_active Expired
- 1976-11-19 NL NL7612932A patent/NL7612932A/xx not_active Application Discontinuation
- 1976-11-19 ES ES453508A patent/ES453508A1/es not_active Expired
- 1976-11-19 CH CH1459976A patent/CH625803A5/de not_active IP Right Cessation
- 1976-11-19 DE DE19762652678 patent/DE2652678A1/de not_active Withdrawn
- 1976-11-19 FR FR7634889A patent/FR2351979A1/fr active Granted
- 1976-11-20 GR GR52224A patent/GR61407B/el unknown
- 1976-11-22 JP JP51139656A patent/JPS5265295A/ja active Pending
- 1976-11-23 ZA ZA00766986A patent/ZA766986B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SE7612295L (sv) | 1977-05-25 |
| FR2351979A1 (fr) | 1977-12-16 |
| PT65845A (en) | 1976-12-01 |
| ZA766986B (en) | 1978-06-28 |
| JPS5265295A (en) | 1977-05-30 |
| PT65845B (en) | 1978-10-10 |
| AU510252B2 (en) | 1980-06-19 |
| AU1964576A (en) | 1978-05-25 |
| GB1561108A (en) | 1980-02-13 |
| FR2351979B1 (enExample) | 1982-08-13 |
| NL7612932A (nl) | 1977-05-26 |
| BE848349A (fr) | 1977-05-16 |
| GR61407B (en) | 1978-11-11 |
| CH625803A5 (en) | 1981-10-15 |
| AR224224A1 (es) | 1981-11-13 |
| DK497476A (da) | 1977-05-25 |
| DE2652678A1 (de) | 1977-06-02 |
| HU175266B (hu) | 1980-06-28 |
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