JPS51133489A - Process for producing microbial components of pseudomonas aeruginosa h aving antimicrobial and antitumor activities - Google Patents

Process for producing microbial components of pseudomonas aeruginosa h aving antimicrobial and antitumor activities

Info

Publication number
JPS51133489A
JPS51133489A JP50055979A JP5597975A JPS51133489A JP S51133489 A JPS51133489 A JP S51133489A JP 50055979 A JP50055979 A JP 50055979A JP 5597975 A JP5597975 A JP 5597975A JP S51133489 A JPS51133489 A JP S51133489A
Authority
JP
Japan
Prior art keywords
aving
antimicrobial
pseudomonas aeruginosa
producing microbial
antitumor activities
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP50055979A
Other languages
Japanese (ja)
Other versions
JPS6123167B2 (en
Inventor
Son Honma
Chiyoji Abe
Kenichi Tanamoto
Kazuo Taruya
Akio Hoshi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Tokyo NUC
Original Assignee
University of Tokyo NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Tokyo NUC filed Critical University of Tokyo NUC
Priority to JP50055979A priority Critical patent/JPS51133489A/en
Priority to GB5938/76A priority patent/GB1537509A/en
Priority to SE7601841A priority patent/SE434701B/en
Priority to NO760646A priority patent/NO148338C/en
Priority to CA246,619A priority patent/CA1060797A/en
Priority to FR7605759A priority patent/FR2311093A1/en
Priority to DE2610504A priority patent/DE2610504C2/en
Priority to US05/668,564 priority patent/US4079126A/en
Publication of JPS51133489A publication Critical patent/JPS51133489A/en
Publication of JPS6123167B2 publication Critical patent/JPS6123167B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/104—Pseudomonadales, e.g. Pseudomonas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/874—Pseudomonas
    • Y10S435/875—Pseudomonas aeruginosa

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

PURPOSE:To elevate remarkably activities such as antitumor, antiviral and specific or non-specific infection protecting activities, etc.
JP50055979A 1975-03-12 1975-05-14 Process for producing microbial components of pseudomonas aeruginosa h aving antimicrobial and antitumor activities Granted JPS51133489A (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP50055979A JPS51133489A (en) 1975-05-14 1975-05-14 Process for producing microbial components of pseudomonas aeruginosa h aving antimicrobial and antitumor activities
GB5938/76A GB1537509A (en) 1975-05-14 1976-02-16 Method of preparing a component consisting of sugar lipid and protein derived from pseudomonas aeruginosa which possesses anti-tumor and interferon-inducing properties
SE7601841A SE434701B (en) 1975-05-14 1976-02-18 SET TO MAKE TUMOR COMBINING INFECTION PREVENTION AND INTERFERON-INducing BACTERIA COMPONENT FROM PSEUDOMONAS AERUGINOSA
NO760646A NO148338C (en) 1975-03-12 1976-02-26 PROCEDURE FOR THE PREPARATION OF ENDOTOXIN PROTEIN FROM THE CELL SLEEVE OF PSEUDOMONAS AERUGINOSA
CA246,619A CA1060797A (en) 1975-05-14 1976-02-26 Isolation of original protein endotoxin from pseudomonas aeruginosa
FR7605759A FR2311093A1 (en) 1975-05-14 1976-03-01 PROCESS FOR THE PREPARATION OF A COMPONENT CONSISTING OF A SUGAR, A LIPID, A PROTEIN, DERIVED FROM PSEUDOMONAS AERUGINOSA WHICH HAS ANTI-TUMOR AND INTERVENTION INDUCTIVE PROPERTIES
DE2610504A DE2610504C2 (en) 1975-05-14 1976-03-12 A sugar, lipoid and protein component derived from Pseudomonas aeruginosa, with anti-tumor and interferon-forming properties
US05/668,564 US4079126A (en) 1975-05-14 1976-03-19 Method of preparing a component consisting of sugar, lipid and protein derived from Pseudomonas aeruginosa which possess anti-tumor and interferon inducing properties

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP50055979A JPS51133489A (en) 1975-05-14 1975-05-14 Process for producing microbial components of pseudomonas aeruginosa h aving antimicrobial and antitumor activities

Publications (2)

Publication Number Publication Date
JPS51133489A true JPS51133489A (en) 1976-11-19
JPS6123167B2 JPS6123167B2 (en) 1986-06-04

Family

ID=13014183

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50055979A Granted JPS51133489A (en) 1975-03-12 1975-05-14 Process for producing microbial components of pseudomonas aeruginosa h aving antimicrobial and antitumor activities

Country Status (7)

Country Link
US (1) US4079126A (en)
JP (1) JPS51133489A (en)
CA (1) CA1060797A (en)
DE (1) DE2610504C2 (en)
FR (1) FR2311093A1 (en)
GB (1) GB1537509A (en)
SE (1) SE434701B (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5296729A (en) * 1976-02-05 1977-08-13 Shionogi & Co Ltd Mixed vaccin for cyanomycosis
CA1085293A (en) * 1976-02-05 1980-09-09 Yuzuru Homma Toxoids derived from protease and elastase of pseudomonas aeruginosa and production thereof
US4479935A (en) * 1980-04-22 1984-10-30 Institut Pasteur Fractions extracted from aerobic bacteria, endowed with antitumoral, antibacterial and interferon inducing properties, and process for their preparation
CA1256370A (en) * 1984-02-24 1989-06-27 Yuzuru Homma Toxoids of elastase of pseudomonas aeruginosa origin
AT384032B (en) * 1985-01-14 1987-09-25 Immuno Ag METHOD FOR PRODUCING POLYDISPERSE NATIVE PSEUDOMONAS-FLAGELLA (H) -ANTIGENS (FAG)
US5179001A (en) * 1985-09-27 1993-01-12 The Regents Of The University Of California Detection and monitoring of chronic and gram-negative infection
AT391080B (en) * 1986-06-24 1990-08-10 Immuno Ag METHOD FOR PRODUCING PREPARATIONS EFFECTIVE OF PSEUDOMONAS AERUGINOSA INFECTIONS
US5237053A (en) * 1986-06-24 1993-08-17 Immuno Aktiengesellschaft Preparation active against Pseudomonas aeruginosa infections and methods of producing them
FR2613380B1 (en) * 1987-04-06 1989-11-17 Pasteur Institut NOVEL ADJUVANT SUBSTANCE OF CERTAIN CHEMICAL ANTIMITOTICS, PROCESS FOR OBTAINING THE SAME FROM VIBRIO CHOLERAE CROPS, THERAPEUTIC AGENTS CONTAINING SAID SUBSTANCE
US6406696B1 (en) 1989-10-27 2002-06-18 Tolerance Therapeutics, Inc. Methods of stimulating the immune system with anti-CD3 antibodies
JP2546544B2 (en) * 1989-10-27 1996-10-23 アーチ ディベラップメント コーポレイション Methods and compositions for promoting immune enhancement
US6491916B1 (en) 1994-06-01 2002-12-10 Tolerance Therapeutics, Inc. Methods and materials for modulation of the immunosuppresive activity and toxicity of monoclonal antibodies
US20030108548A1 (en) * 1993-06-01 2003-06-12 Bluestone Jeffrey A. Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies
CA2614640A1 (en) * 2005-07-11 2007-01-18 Macrogenics, Inc. Methods for the treatment of autoimmune disorders using immunosuppressive monoclonal antibodies with reduced toxicity
SG10201504662WA (en) * 2006-06-14 2015-07-30 Macrogenics Inc Methods For The Treatment Of Autoimmune Disorders Using Immunosuppressive Monoclonal Antibodies With Reduced Toxicity
WO2008079713A2 (en) * 2006-12-21 2008-07-03 Macrogenics Inc. Methods for the treatment of lada and other adult-onset autoimmune diabetes using immunosuppressive monoclonal antibodies with reduced toxicity
EA201391262A1 (en) * 2011-03-02 2014-03-31 Джером Шентаг COMPOSITION, METHOD OF TREATMENT AND DIAGNOSTICS OF LIVER STEATOSIS AS AN INDEPENDENT DISEASE OR IN COMBINATION WITH HEPATITIS C INFECTION
CN109401992B (en) * 2017-08-18 2021-07-23 黑龙江省科学院微生物研究所 A high-producing endotoxin protein Pseudomonas aeruginosa and its application
MX2023013851A (en) 2021-05-24 2023-12-08 Provention Bio Inc METHODS FOR THE TREATMENT OF TYPE 1 DIABETES.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS496096B1 (en) * 1970-09-30 1974-02-12
DE2152112C3 (en) * 1970-10-20 1979-10-11 Yuzuru Homma Vaccine against Pseudomonas aeruginosa
FR2184531B1 (en) * 1972-05-19 1975-10-17 Anvar

Also Published As

Publication number Publication date
CA1060797A (en) 1979-08-21
SE434701B (en) 1984-08-13
US4079126A (en) 1978-03-14
GB1537509A (en) 1978-12-29
FR2311093B1 (en) 1979-06-29
DE2610504C2 (en) 1985-07-11
SE7601841L (en) 1976-11-15
FR2311093A1 (en) 1976-12-10
DE2610504A1 (en) 1976-11-25
JPS6123167B2 (en) 1986-06-04

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