ES450859A1 - Procedimiento para preparar 2,6-antraquinonilenamidinas. - Google Patents
Procedimiento para preparar 2,6-antraquinonilenamidinas.Info
- Publication number
- ES450859A1 ES450859A1 ES450859A ES450859A ES450859A1 ES 450859 A1 ES450859 A1 ES 450859A1 ES 450859 A ES450859 A ES 450859A ES 450859 A ES450859 A ES 450859A ES 450859 A1 ES450859 A1 ES 450859A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- phenyl
- alkyl
- anthraquinonlyene
- amidines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/195—Radicals derived from nitrogen analogues of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/12—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Procedimiento para preparar 2,6-antraquinonilenamidinas, de fórmula: **(Fórmula 1)** donde R1 es hidrógeno, alquilo, alquilo ramificado, cicloalquilo (C1-C15), heterocíclico, fenilo o fenilo substituido; donde R2 es un amino substituido **(Fórmula 2)** en donde R3 y R4 son hidrógeno, fenilo o fenilo substituido, alquilo o alquilo ramificado, y donde R3 y R4 se toman juntamente para formar anillos heterocíclicos, y sales farmacéuticamente aceptables del mismo, caracterizado porque comprende hacer reaccionar 2,6-diaminoantraquinona con un complejo formado mezclando oxicloruro fosforoso y una N,N-dialquilamida o N-alquilamida en un solvente inerte a una temperatura de aproximadamente 25º a 70ºC durante un periodo de aproximadamente 1 a 24 horas.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US60680575A | 1975-08-22 | 1975-08-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES450859A1 true ES450859A1 (es) | 1978-04-01 |
Family
ID=24429543
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES450859A Expired ES450859A1 (es) | 1975-08-22 | 1976-08-20 | Procedimiento para preparar 2,6-antraquinonilenamidinas. |
Country Status (21)
Country | Link |
---|---|
JP (1) | JPS5225763A (es) |
AR (1) | AR213625A1 (es) |
AU (1) | AU508586B2 (es) |
BE (1) | BE845369A (es) |
CA (1) | CA1098127A (es) |
CS (1) | CS212773B2 (es) |
DE (1) | DE2637544A1 (es) |
EG (1) | EG12401A (es) |
ES (1) | ES450859A1 (es) |
FR (1) | FR2321281A1 (es) |
GB (1) | GB1553600A (es) |
GR (1) | GR60420B (es) |
HU (1) | HU173298B (es) |
LU (1) | LU75636A1 (es) |
NL (1) | NL7609230A (es) |
NZ (1) | NZ181596A (es) |
PH (1) | PH13216A (es) |
PL (1) | PL191945A1 (es) |
PT (1) | PT65506B (es) |
SU (1) | SU883002A1 (es) |
ZA (1) | ZA764516B (es) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1154489B (de) * | 1961-05-05 | 1963-09-19 | Basf Ag | Verfahren zur Trennung von Mono- und Diaminoanthrachinonen |
-
1976
- 1976-07-27 ZA ZA764516A patent/ZA764516B/xx unknown
- 1976-07-30 PH PH18739A patent/PH13216A/en unknown
- 1976-08-03 GB GB31334/76A patent/GB1553600A/en not_active Expired
- 1976-08-05 NZ NZ181596A patent/NZ181596A/xx unknown
- 1976-08-06 AR AR264245A patent/AR213625A1/es active
- 1976-08-06 GR GR51428A patent/GR60420B/el unknown
- 1976-08-09 AU AU16693/76A patent/AU508586B2/en not_active Expired
- 1976-08-12 CA CA257,701A patent/CA1098127A/en not_active Expired
- 1976-08-14 EG EG498/76A patent/EG12401A/xx active
- 1976-08-18 HU HU76AE473A patent/HU173298B/hu unknown
- 1976-08-19 NL NL7609230A patent/NL7609230A/xx not_active Application Discontinuation
- 1976-08-19 FR FR7625243A patent/FR2321281A1/fr active Granted
- 1976-08-19 SU SU762389053A patent/SU883002A1/ru active
- 1976-08-20 LU LU75636A patent/LU75636A1/xx unknown
- 1976-08-20 BE BE169950A patent/BE845369A/xx not_active IP Right Cessation
- 1976-08-20 ES ES450859A patent/ES450859A1/es not_active Expired
- 1976-08-20 CS CS765425A patent/CS212773B2/cs unknown
- 1976-08-20 DE DE19762637544 patent/DE2637544A1/de not_active Withdrawn
- 1976-08-20 PT PT65506A patent/PT65506B/pt unknown
- 1976-08-21 PL PL19194576A patent/PL191945A1/xx unknown
- 1976-08-23 JP JP51099760A patent/JPS5225763A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
PL191945A1 (pl) | 1978-12-04 |
AR213625A1 (es) | 1979-02-28 |
NL7609230A (nl) | 1977-02-24 |
AU1669376A (en) | 1978-02-16 |
HU173298B (hu) | 1979-04-28 |
ZA764516B (en) | 1977-07-27 |
CS212773B2 (en) | 1982-03-26 |
GB1553600A (en) | 1979-09-26 |
FR2321281A1 (fr) | 1977-03-18 |
JPS5225763A (en) | 1977-02-25 |
NZ181596A (en) | 1978-12-18 |
BE845369A (fr) | 1977-02-21 |
CA1098127A (en) | 1981-03-24 |
PT65506A (en) | 1976-09-01 |
FR2321281B1 (es) | 1979-07-27 |
DE2637544A1 (de) | 1977-03-03 |
LU75636A1 (es) | 1977-03-29 |
GR60420B (en) | 1978-05-25 |
PH13216A (en) | 1980-02-07 |
EG12401A (en) | 1980-03-31 |
AU508586B2 (en) | 1980-03-27 |
PT65506B (en) | 1978-02-15 |
SU883002A1 (ru) | 1981-11-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19990503 |