ES450740A1 - Procedimiento para preparar derivados de vincamina. - Google Patents
Procedimiento para preparar derivados de vincamina.Info
- Publication number
- ES450740A1 ES450740A1 ES450740A ES450740A ES450740A1 ES 450740 A1 ES450740 A1 ES 450740A1 ES 450740 A ES450740 A ES 450740A ES 450740 A ES450740 A ES 450740A ES 450740 A1 ES450740 A1 ES 450740A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- vincamine derivatives
- derivatives
- see formula
- hydrolyzed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1768973A CH588488A5 (en) | 1973-12-18 | 1973-12-18 | Vincamine derivs for treating behaviour disorders - by ring closure of indoloquinolizine deriv |
| CH162174A CH596207A5 (en) | 1974-02-06 | 1974-02-06 | Vincamine derivs for treating behaviour disorders |
| CH176574A CH593283A5 (en) | 1974-02-08 | 1974-02-08 | Vincamine derivs for treating behaviour disorders - by ring closure of indoloquinolizine deriv |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES450740A1 true ES450740A1 (es) | 1977-12-16 |
Family
ID=27173122
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES432952A Expired ES432952A1 (es) | 1973-12-18 | 1974-12-16 | Procedimiento para preparar derivado de vincamina. |
| ES450740A Expired ES450740A1 (es) | 1973-12-18 | 1976-08-16 | Procedimiento para preparar derivados de vincamina. |
| ES450741A Expired ES450741A1 (es) | 1973-12-18 | 1976-08-16 | Procedimiento para preparar derivados de vincamina. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES432952A Expired ES432952A1 (es) | 1973-12-18 | 1974-12-16 | Procedimiento para preparar derivado de vincamina. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES450741A Expired ES450741A1 (es) | 1973-12-18 | 1976-08-16 | Procedimiento para preparar derivados de vincamina. |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPS5817474B2 (es) |
| CA (1) | CA1051899A (es) |
| DD (1) | DD116043A5 (es) |
| DE (1) | DE2458164A1 (es) |
| DK (1) | DK139358B (es) |
| ES (3) | ES432952A1 (es) |
| FI (1) | FI59096C (es) |
| FR (1) | FR2254342B1 (es) |
| GB (1) | GB1492579A (es) |
| HK (1) | HK53980A (es) |
| IE (1) | IE40791B1 (es) |
| MY (1) | MY8100186A (es) |
| NL (1) | NL7416237A (es) |
| NO (1) | NO744456L (es) |
| PH (1) | PH12927A (es) |
| SE (1) | SE422798B (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2396759A1 (fr) * | 1977-07-06 | 1979-02-02 | Omnium Chimique Sa | Nouveaux composes heterocycliques, derives de la vincamine, leur preparation et leur application comme medicaments, notamment dans le domaine des insuffisances cardio-circulatoires, cerebro-vasculaires ou respiratoires |
| HU177498B (en) * | 1977-07-27 | 1981-10-28 | Richter Gedeon Vegyeszet | Process for preparing new vincinic acid and apovincinic acid esters |
| FR2423493A1 (fr) * | 1977-10-19 | 1979-11-16 | Omnium Chimique Sa | Nouveaux composes heterocycliques derives de l'apo-vincamine, leur preparation et leur application comme medicaments, notamment dans le domaine des insuffisances cardio-circulatoires, cerebro-vasculaires et respiratoires |
| FR2407931A1 (fr) * | 1977-11-02 | 1979-06-01 | Synthelabo | Derives de l'eburnamenine et leur application en therapeutique |
| JPS5493000A (en) * | 1977-12-28 | 1979-07-23 | Sandoz Ag | Improvement of organic compound |
| DE2800063A1 (de) * | 1978-01-02 | 1979-07-12 | Sandoz Ag | 10-bromvincamin, seine herstellung und verwendung |
| FR2445328A1 (fr) * | 1978-07-12 | 1980-07-25 | Richter Gedeon Vegyeszet | Derives du 14-oxo-e-homo-eburnane, leur procede de preparation et leur utilisation comme medicament |
| US4315011A (en) * | 1978-07-12 | 1982-02-09 | Richter Gedeon Vegyeszeti Gyar Rt. | 1-Alkyl-9-bromohexahydroindolo quinolizium salts and use thereof to increase blood flow |
| US4285949A (en) * | 1978-12-11 | 1981-08-25 | Omnichem Societe Anonyme | Vincamine derivatives, their preparation and therapeutical use |
| HU177732B (en) * | 1978-12-15 | 1981-12-28 | Richter Gedeon Vegyeszet | Process for producing 10-bromo-vincamine and acid additional salts thereof,and 10-bromo-14-epivincamine |
| HU180928B (en) * | 1979-08-06 | 1983-05-30 | Richter Gedeon Vegyeszet | Process for preparing new brominated 15-hydroxy-e-homo-eburane derivatives |
| HU180929B (en) * | 1979-08-13 | 1983-05-30 | Richter Gedeon Vegyeszet | Process for producing new bromo-vincamone derivatives |
| HU185305B (en) * | 1981-08-23 | 1985-01-28 | Richter Gedeon Vegyeszet | Process for preparing vincine and apovincine |
| HU183326B (en) * | 1981-02-11 | 1984-04-28 | Richter Gedeon Vegyeszet | Process for preparing new apovincaminol-3',4',5'-trimethoxy-benzoates substituted in the a ring and acid addition salts thereof |
| ES8604952A1 (es) * | 1985-11-05 | 1986-03-16 | Covex Sa | Procedimiento para la preparacion de los compuestos 10-11 bromo-14,15-dihidro-14 b-hidroxi-(3x,16x)-eburnamenina-14- carboxilato de metilo |
| US4883876A (en) * | 1987-09-07 | 1989-11-28 | Taisho Pharmaceutical Co., Ltd. | Acylated vincaminic acid derivatives |
-
1974
- 1974-12-09 DK DK639774AA patent/DK139358B/da not_active IP Right Cessation
- 1974-12-09 DE DE19742458164 patent/DE2458164A1/de active Granted
- 1974-12-09 SE SE7415416A patent/SE422798B/xx not_active IP Right Cessation
- 1974-12-10 NO NO744456A patent/NO744456L/no unknown
- 1974-12-10 FI FI3552/74A patent/FI59096C/fi active
- 1974-12-13 NL NL7416237A patent/NL7416237A/xx not_active Application Discontinuation
- 1974-12-16 GB GB54159/74A patent/GB1492579A/en not_active Expired
- 1974-12-16 PH PH16634A patent/PH12927A/en unknown
- 1974-12-16 IE IE2591/74A patent/IE40791B1/xx unknown
- 1974-12-16 ES ES432952A patent/ES432952A1/es not_active Expired
- 1974-12-17 DD DD183107A patent/DD116043A5/xx unknown
- 1974-12-17 JP JP49144170A patent/JPS5817474B2/ja not_active Expired
- 1974-12-17 CA CA216,230A patent/CA1051899A/en not_active Expired
- 1974-12-18 FR FR7441717A patent/FR2254342B1/fr not_active Expired
-
1976
- 1976-08-16 ES ES450740A patent/ES450740A1/es not_active Expired
- 1976-08-16 ES ES450741A patent/ES450741A1/es not_active Expired
-
1980
- 1980-09-25 HK HK539/80A patent/HK53980A/xx unknown
-
1981
- 1981-12-30 MY MY186/81A patent/MY8100186A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU7648374A (en) | 1976-06-17 |
| DE2458164A1 (de) | 1975-06-26 |
| DK139358C (es) | 1979-07-09 |
| IE40791L (en) | 1975-06-18 |
| FR2254342A1 (es) | 1975-07-11 |
| FI59096B (fi) | 1981-02-27 |
| IE40791B1 (en) | 1979-08-15 |
| MY8100186A (en) | 1981-12-31 |
| DD116043A5 (es) | 1975-11-05 |
| DK639774A (es) | 1975-08-25 |
| NO744456L (es) | 1975-07-14 |
| SE7415416L (es) | 1975-06-19 |
| HK53980A (en) | 1980-10-03 |
| FI355274A (es) | 1975-06-19 |
| PH12927A (en) | 1979-10-10 |
| JPS5817474B2 (ja) | 1983-04-07 |
| ES432952A1 (es) | 1977-02-16 |
| NL7416237A (nl) | 1975-06-20 |
| DK139358B (da) | 1979-02-05 |
| FR2254342B1 (es) | 1978-07-21 |
| ES450741A1 (es) | 1978-03-16 |
| GB1492579A (en) | 1977-11-23 |
| SE422798B (sv) | 1982-03-29 |
| JPS50105700A (es) | 1975-08-20 |
| CA1051899A (en) | 1979-04-03 |
| DE2458164C2 (es) | 1991-04-18 |
| FI59096C (fi) | 1981-06-10 |
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