ES443790A1 - Un procedimiento para la preparacion de derivados de bencil-pirimidina. - Google Patents

Un procedimiento para la preparacion de derivados de bencil-pirimidina.

Info

Publication number
ES443790A1
ES443790A1 ES443790A ES443790A ES443790A1 ES 443790 A1 ES443790 A1 ES 443790A1 ES 443790 A ES443790 A ES 443790A ES 443790 A ES443790 A ES 443790A ES 443790 A1 ES443790 A1 ES 443790A1
Authority
ES
Spain
Prior art keywords
amino
groups
compounds
pyrrolidino
piperidino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES443790A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES443790A1 publication Critical patent/ES443790A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C07D207/327Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
ES443790A 1974-12-24 1975-12-23 Un procedimiento para la preparacion de derivados de bencil-pirimidina. Expired ES443790A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1728774A CH605828A5 (me) 1974-12-24 1974-12-24

Publications (1)

Publication Number Publication Date
ES443790A1 true ES443790A1 (es) 1977-12-16

Family

ID=4424233

Family Applications (1)

Application Number Title Priority Date Filing Date
ES443790A Expired ES443790A1 (es) 1974-12-24 1975-12-23 Un procedimiento para la preparacion de derivados de bencil-pirimidina.

Country Status (25)

Country Link
JP (1) JPS5191273A (me)
AT (1) AT344704B (me)
AU (1) AU500102B2 (me)
BE (1) BE836996A (me)
BR (1) BR7508534A (me)
CA (1) CA1059127A (me)
CH (2) CH605828A5 (me)
CU (1) CU34406A (me)
DD (1) DD123603A5 (me)
DE (1) DE2558150A1 (me)
DK (1) DK137797B (me)
ES (1) ES443790A1 (me)
FI (1) FI753312A (me)
FR (1) FR2295750A1 (me)
GB (1) GB1492140A (me)
HU (1) HU174324B (me)
IL (1) IL48416A (me)
LU (1) LU73971A1 (me)
NL (1) NL7514269A (me)
NO (1) NO141408C (me)
PH (1) PH12314A (me)
PL (1) PL101046B1 (me)
SE (1) SE417607B (me)
SU (1) SU612629A3 (me)
ZA (1) ZA756964B (me)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR71725B (me) * 1977-11-10 1983-06-22 Hoffmann La Roche
US9567318B2 (en) * 2009-08-17 2017-02-14 Memorial Sloan-Kettering Cancer Center Substituted pyrimidine compounds and uses thereof
JP6607870B2 (ja) 2014-05-13 2019-11-20 メモリアル スローン ケタリング キャンサー センター Hsp70モジュレーターならびにその作製および使用方法

Also Published As

Publication number Publication date
SU612629A3 (ru) 1978-06-25
DK137797C (me) 1978-10-16
IL48416A (en) 1980-02-29
NL7514269A (nl) 1976-06-28
CU34406A (es) 1978-09-08
BE836996A (fr) 1976-06-23
SE417607B (sv) 1981-03-30
PL101046B1 (pl) 1978-11-30
CH605828A5 (me) 1978-10-13
SE7514642L (sv) 1976-06-28
ZA756964B (en) 1976-10-27
ATA975975A (de) 1977-12-15
IL48416A0 (en) 1976-01-30
JPS5191273A (me) 1976-08-10
DD123603A5 (me) 1977-01-05
NO141408C (no) 1980-03-05
PH12314A (en) 1979-01-16
FR2295750A1 (fr) 1976-07-23
HU174324B (hu) 1979-12-28
AT344704B (de) 1978-08-10
DK137797B (da) 1978-05-08
NO754372L (me) 1976-06-25
CH617191A5 (en) 1980-05-14
DK589675A (me) 1976-06-25
FI753312A (me) 1976-06-25
BR7508534A (pt) 1976-12-21
FR2295750B1 (me) 1980-06-20
LU73971A1 (me) 1977-07-01
NO141408B (no) 1979-11-26
GB1492140A (en) 1977-11-16
CA1059127A (en) 1979-07-24
AU8643375A (en) 1977-05-12
AU500102B2 (en) 1979-05-10
DE2558150A1 (de) 1976-07-01

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