ES432441A1 - Quinolone derivatives - Google Patents

Quinolone derivatives

Info

Publication number
ES432441A1
ES432441A1 ES432441A ES432441A ES432441A1 ES 432441 A1 ES432441 A1 ES 432441A1 ES 432441 A ES432441 A ES 432441A ES 432441 A ES432441 A ES 432441A ES 432441 A1 ES432441 A1 ES 432441A1
Authority
ES
Spain
Prior art keywords
group
general formula
acyloxy
see formula
alcoholic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES432441A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of ES432441A1 publication Critical patent/ES432441A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/06Ring systems of three rings
    • C07D221/10Aza-phenanthrenes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/06Ring systems of three rings
    • C07D221/16Ring systems of three rings containing carbocyclic rings other than six-membered

Abstract

Procedure for the preparation of quinolone derivatives of the general formula I **(See formula)** wherein it means hydrogen, an alcoholic or lower alkenyl group; R3 stands for hydrogen or a lower alcohol group and n stands for numbers 1 or 2, as well as for its pharmacologically compatible salts, characterized in that a) it is treated with agents that separate HX from substances of the general formula II **(See formula)** wherein R1, R3 and n have the meanings mentioned above and X signifies a hydroxyl, acyloxy or lower alkoxy group, or halogen; or b) compounds of the general formula III are cyclized, under HX'separation conditions **(See formula)** Where n and R3 have the meanings mentioned above, it means a lower alcohol or aiquenyl group and X'means a hydroxyl, acyloxy or lower alkoxy group; and optionally subsequently alcoholic (or alkenyl) together with the nitrogen atom and/or the 3-position substituent is esterified or saponified, as well as transformed into the pharmacologically compatible salts. (Machine-translation by Google Translate, not legally binding)
ES432441A 1973-12-05 1974-11-29 Quinolone derivatives Expired ES432441A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2360473A DE2360473A1 (en) 1973-12-05 1973-12-05 Quinolone derivatives and their production process

Publications (1)

Publication Number Publication Date
ES432441A1 true ES432441A1 (en) 1976-11-16

Family

ID=5899873

Family Applications (1)

Application Number Title Priority Date Filing Date
ES432441A Expired ES432441A1 (en) 1973-12-05 1974-11-29 Quinolone derivatives

Country Status (11)

Country Link
JP (1) JPS5084573A (en)
AT (1) AT339309B (en)
CA (1) CA1037045A (en)
DE (1) DE2360473A1 (en)
ES (1) ES432441A1 (en)
FI (1) FI345974A (en)
FR (1) FR2253521B1 (en)
GB (1) GB1438219A (en)
NL (1) NL7415679A (en)
SE (1) SE7414928L (en)
ZA (1) ZA747598B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115286575A (en) * 2022-06-24 2022-11-04 河南科技大学 Quinolinone seven-eight membered ring derivative and synthesis method and application thereof

Also Published As

Publication number Publication date
GB1438219A (en) 1976-06-03
JPS5084573A (en) 1975-07-08
FR2253521B1 (en) 1978-07-21
SE7414928L (en) 1975-06-06
DE2360473A1 (en) 1975-06-19
FR2253521A1 (en) 1975-07-04
AT339309B (en) 1977-10-10
FI345974A (en) 1975-06-06
ATA967874A (en) 1977-02-15
NL7415679A (en) 1975-06-09
ZA747598B (en) 1976-01-28
AU7591574A (en) 1976-06-03
CA1037045A (en) 1978-08-22

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