ES455085A1 - Derivatives of sandwicine and isosandwicine and pharmaceutical compositions comprising sandwicine isosandwicine and derivatives thereof - Google Patents

Derivatives of sandwicine and isosandwicine and pharmaceutical compositions comprising sandwicine isosandwicine and derivatives thereof

Info

Publication number
ES455085A1
ES455085A1 ES455085A ES455085A ES455085A1 ES 455085 A1 ES455085 A1 ES 455085A1 ES 455085 A ES455085 A ES 455085A ES 455085 A ES455085 A ES 455085A ES 455085 A1 ES455085 A1 ES 455085A1
Authority
ES
Spain
Prior art keywords
derivatives
isosandwicine
sandwicine
acyloxy
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES455085A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Inverni Della Beffa SpA
Original Assignee
Inverni Della Beffa SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inverni Della Beffa SpA filed Critical Inverni Della Beffa SpA
Publication of ES455085A1 publication Critical patent/ES455085A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Procedure for the preparation of sandwicin derivatives, of general formula: ** (Formula) ** in which R3 is alcoholic or substituted alcoholic, R4 is hydroxy or acyloxy, X is a pharmacologically acceptable anion and either R5 is alpha- OH or alpha-acyloxy and R6 is beta-ethyl, or R5 is beta-OH or beta-acyloxy and R6 is high-ethyl with the proviso that when R5 is alpha-acyloxy, R4 is also acyloxy. (Machine-translation by Google Translate, not legally binding)
ES455085A 1976-01-16 1977-01-15 Derivatives of sandwicine and isosandwicine and pharmaceutical compositions comprising sandwicine isosandwicine and derivatives thereof Expired ES455085A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1769/76A GB1582627A (en) 1976-01-16 1976-01-16 Derivatives of sandwicine and isosandwicine and pharmaceutical compositions comprising sandwicine isosandwicine and derivatives thereof

Publications (1)

Publication Number Publication Date
ES455085A1 true ES455085A1 (en) 1978-04-16

Family

ID=9727661

Family Applications (1)

Application Number Title Priority Date Filing Date
ES455085A Expired ES455085A1 (en) 1976-01-16 1977-01-15 Derivatives of sandwicine and isosandwicine and pharmaceutical compositions comprising sandwicine isosandwicine and derivatives thereof

Country Status (8)

Country Link
JP (1) JPS5289686A (en)
BE (1) BE850342A (en)
DE (1) DE2701417A1 (en)
ES (1) ES455085A1 (en)
FR (1) FR2338276A1 (en)
GB (1) GB1582627A (en)
GR (1) GR59327B (en)
PT (1) PT66064B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2611162A1 (en) * 1976-03-17 1977-10-06 Kali Chemie Pharma Gmbh NEW QUARTERLY DERIVATIVES OF SANDWICIN AND THE METHOD FOR THEIR PRODUCTION
DE2941531A1 (en) * 1979-10-13 1981-04-23 Kali-Chemie Pharma Gmbh, 3000 Hannover 10-BROMSANDWICIN AND 10-BROMISOSANDWICIN, METHOD FOR THE PRODUCTION AND USE THEREOF
DE2941530A1 (en) * 1979-10-13 1981-04-23 Kali-Chemie Pharma Gmbh, 3000 Hannover N (DOWN ARROW) B (UP ARROW) QUARTERS DERIVATIVES OF SANDWICIN AND ISOSANDWICIN, METHODS AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION OF THE DERIVATIVES, THE MEDICINAL PRODUCT CONTAINING THE DERIVATIVES AND THE USE OF THE DERIVATIVES

Also Published As

Publication number Publication date
FR2338276A1 (en) 1977-08-12
GB1582627A (en) 1981-01-14
FR2338276B1 (en) 1981-07-24
JPS5289686A (en) 1977-07-27
DE2701417A1 (en) 1977-07-28
PT66064A (en) 1977-02-01
PT66064B (en) 1978-06-23
BE850342A (en) 1977-05-02
GR59327B (en) 1977-12-13

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19990503