ES437099A1 - D-homosteroid lactones - Google Patents
D-homosteroid lactonesInfo
- Publication number
- ES437099A1 ES437099A1 ES437099A ES437099A ES437099A1 ES 437099 A1 ES437099 A1 ES 437099A1 ES 437099 A ES437099 A ES 437099A ES 437099 A ES437099 A ES 437099A ES 437099 A1 ES437099 A1 ES 437099A1
- Authority
- ES
- Spain
- Prior art keywords
- methyl group
- dashed lines
- general formula
- homosteroid
- lactones
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Steroid Compounds (AREA)
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A procedure for the preparation of D-homosteroids, of the general formula **(See formula)** in which dashed lines at positions 1,2-, 6,7- and 16,17 denote optional bonds, R10 represents a hydrogen atom or a methyl group when a single bond is present at position 1,2 or a methyl group when I have a double bond in position 1,2 whose process is characterized in that it comprises dehydrogenating a D-homoesteroid of the general formula **(See formula)** in which R10 and the dashed lines at position 6,7- and 16,17 have the meaning indicated above, at position 1,2- and/or 6,7 (only at position 1,2 when R10 represents a methyl group). (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1376373A CH601352A5 (en) | 1973-09-26 | 1973-09-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES437099A1 true ES437099A1 (en) | 1977-01-16 |
Family
ID=4395102
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES430369A Expired ES430369A1 (en) | 1973-09-26 | 1974-09-24 | D-homosteroid lactones |
| ES437100A Expired ES437100A1 (en) | 1973-09-26 | 1975-04-28 | D-homosteroid lactones |
| ES437101A Expired ES437101A1 (en) | 1973-09-26 | 1975-04-28 | D-homosteroid lactones |
| ES437099A Expired ES437099A1 (en) | 1973-09-26 | 1975-04-28 | D-homosteroid lactones |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES430369A Expired ES430369A1 (en) | 1973-09-26 | 1974-09-24 | D-homosteroid lactones |
| ES437100A Expired ES437100A1 (en) | 1973-09-26 | 1975-04-28 | D-homosteroid lactones |
| ES437101A Expired ES437101A1 (en) | 1973-09-26 | 1975-04-28 | D-homosteroid lactones |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US3920703A (en) |
| JP (1) | JPS5058054A (en) |
| AR (2) | AR207230A1 (en) |
| AT (1) | AT337915B (en) |
| BE (1) | BE820303A (en) |
| CA (1) | CA1025435A (en) |
| CH (1) | CH601352A5 (en) |
| CS (1) | CS178930B2 (en) |
| DD (1) | DD115492A5 (en) |
| DE (1) | DE2445783A1 (en) |
| DK (1) | DK135723B (en) |
| EG (1) | EG11189A (en) |
| ES (4) | ES430369A1 (en) |
| FI (1) | FI53709C (en) |
| FR (1) | FR2244497B1 (en) |
| GB (1) | GB1450884A (en) |
| HU (1) | HU172656B (en) |
| IE (1) | IE39913B1 (en) |
| IL (1) | IL45483A (en) |
| LU (1) | LU70980A1 (en) |
| NL (1) | NL7411617A (en) |
| NO (1) | NO140305C (en) |
| PH (1) | PH10616A (en) |
| PL (2) | PL94256B1 (en) |
| SE (1) | SE7411948L (en) |
| SU (2) | SU612637A3 (en) |
| ZA (1) | ZA745197B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4155918A (en) * | 1976-10-28 | 1979-05-22 | Hoffmann-La Roche Inc. | Novel D-homosteroids |
| DE2652761C2 (en) * | 1976-11-16 | 1985-11-21 | Schering AG, 1000 Berlin und 4709 Bergkamen | 15,16-methylene-spirolactones, processes for their preparation and pharmaceuticals containing them |
| AT351191B (en) * | 1976-12-20 | 1979-07-10 | Hoffmann La Roche | METHOD FOR PRODUCING NEW D-HOMOSTEROIDS |
| LU77699A1 (en) * | 1977-07-06 | 1979-03-26 | Hoffmann La Roche | METHOD FOR PRODUCING NEW D-HOMOSTEROIDS |
| CA1195997A (en) * | 1979-02-23 | 1985-10-29 | Andor Furst | Dea-steroids |
| DK23984A (en) * | 1983-02-11 | 1984-08-12 | Hoffmann La Roche | D-homosteroids |
| DE3461090D1 (en) * | 1983-02-18 | 1986-12-04 | Schering Ag | 11-beta-aryl-estradienes, process for their preparation and pharmaceutical compositions containing them |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3758508A (en) * | 1964-09-29 | 1973-09-11 | Hoffmann La Roche | Ted derivatives thereof process for the preparation of desaandrostanes pregnanes and unsatura |
-
1973
- 1973-09-26 CH CH1376373A patent/CH601352A5/xx not_active IP Right Cessation
-
1974
- 1974-01-01 AR AR255747A patent/AR207230A1/en active
- 1974-08-13 ZA ZA00745197A patent/ZA745197B/en unknown
- 1974-08-16 IL IL45483A patent/IL45483A/en unknown
- 1974-09-02 NL NL7411617A patent/NL7411617A/en not_active Application Discontinuation
- 1974-09-20 PH PH16316A patent/PH10616A/en unknown
- 1974-09-23 IE IE1962/74A patent/IE39913B1/en unknown
- 1974-09-23 SE SE7411948A patent/SE7411948L/en unknown
- 1974-09-23 US US508127A patent/US3920703A/en not_active Expired - Lifetime
- 1974-09-23 FI FI2766/74A patent/FI53709C/en active
- 1974-09-24 ES ES430369A patent/ES430369A1/en not_active Expired
- 1974-09-24 FR FR7432163A patent/FR2244497B1/fr not_active Expired
- 1974-09-24 DD DD181283A patent/DD115492A5/xx unknown
- 1974-09-24 LU LU70980A patent/LU70980A1/xx unknown
- 1974-09-24 JP JP49108924A patent/JPS5058054A/ja active Pending
- 1974-09-24 EG EG442/74A patent/EG11189A/en active
- 1974-09-25 GB GB4170674A patent/GB1450884A/en not_active Expired
- 1974-09-25 AT AT771874A patent/AT337915B/en not_active IP Right Cessation
- 1974-09-25 PL PL1974174322A patent/PL94256B1/pl unknown
- 1974-09-25 CA CA210,036A patent/CA1025435A/en not_active Expired
- 1974-09-25 DE DE19742445783 patent/DE2445783A1/en not_active Ceased
- 1974-09-25 CS CS7400006583A patent/CS178930B2/en unknown
- 1974-09-25 DK DK504574AA patent/DK135723B/en unknown
- 1974-09-25 PL PL1974183651A patent/PL92396B1/pl unknown
- 1974-09-25 BE BE148857A patent/BE820303A/en unknown
- 1974-09-25 NO NO743467A patent/NO140305C/en unknown
- 1974-09-25 HU HU74HO00001725A patent/HU172656B/en unknown
- 1974-09-25 SU SU742062767A patent/SU612637A3/en active
-
1975
- 1975-01-01 AR AR259038A patent/AR206632A1/en active
- 1975-04-28 ES ES437100A patent/ES437100A1/en not_active Expired
- 1975-04-28 ES ES437101A patent/ES437101A1/en not_active Expired
- 1975-04-28 ES ES437099A patent/ES437099A1/en not_active Expired
- 1975-05-27 SU SU752136809A patent/SU626706A3/en active
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