ES402648A1 - Hydroxycrotonic acid derivatives - Google Patents

Hydroxycrotonic acid derivatives

Info

Publication number
ES402648A1
ES402648A1 ES402648A ES402648A ES402648A1 ES 402648 A1 ES402648 A1 ES 402648A1 ES 402648 A ES402648 A ES 402648A ES 402648 A ES402648 A ES 402648A ES 402648 A1 ES402648 A1 ES 402648A1
Authority
ES
Spain
Prior art keywords
general formula
radical
salts
carbon atoms
organic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES402648A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES402648A1 publication Critical patent/ES402648A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/56Unsaturated compounds containing hydroxy or O-metal groups containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/72Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/76Unsaturated compounds containing keto groups
    • C07C59/88Unsaturated compounds containing keto groups containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/76Unsaturated compounds containing keto groups
    • C07C59/90Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Procedure for the preparation of hydroxycotonic acids of the general formula I **(See formula)** where R is a branched or unbranched alcohol radical with 1 to 8 carbon atoms, a 5-, 6- or 7-membered cycloalkoxy radical, which may optionally be substituted by an alcohol radical with 1 to 3 carbon atoms or a group cyano, a pyrrolidino or piperidino radical or the allyloxy group; and X signifies a halogen atom or the nitro, cyano or methoxy group, and of its salts with organic or inorganic bases, characterized in that an oxochrotonic acid of the general formula II is reduced **(See formula)** wherein the radicals R and X are as defined above, and eventually a compound thus obtained of the general formula I is transformed into its salts by means of organic or inorganic bases. (Machine-translation by Google Translate, not legally binding)
ES402648A 1971-05-13 1972-05-12 Hydroxycrotonic acid derivatives Expired ES402648A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19712123858 DE2123858A1 (en) 1971-05-13 1971-05-13

Publications (1)

Publication Number Publication Date
ES402648A1 true ES402648A1 (en) 1975-03-16

Family

ID=5807798

Family Applications (1)

Application Number Title Priority Date Filing Date
ES402648A Expired ES402648A1 (en) 1971-05-13 1972-05-12 Hydroxycrotonic acid derivatives

Country Status (8)

Country Link
AT (1) AT319206B (en)
AU (1) AU4222572A (en)
BE (1) BE783424A (en)
DE (1) DE2123858A1 (en)
ES (1) ES402648A1 (en)
FR (1) FR2137844B1 (en)
GB (1) GB1388146A (en)
NL (1) NL7206399A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3600401A1 (en) * 1986-01-09 1987-07-16 Henkel Kgaa USE OF ALKYLBENZOYL ACRYLIC ACIDS AS CORROSION INHIBITORS
FR2817256B1 (en) * 2000-11-27 2005-07-15 Univ Pasteur DERIVATIVES OF 4-HYDROXYBUTANOIC ACID AND ITS SUPERIOR APPROACHES AS GAMMA-HYDROXYBUTYRATE (GHB) RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND PHARMACEUTICAL USES

Also Published As

Publication number Publication date
AU4222572A (en) 1973-11-15
FR2137844A1 (en) 1972-12-29
DE2123858A1 (en) 1972-12-07
BE783424A (en) 1972-11-13
FR2137844B1 (en) 1975-10-17
GB1388146A (en) 1975-03-26
AT319206B (en) 1974-12-10
NL7206399A (en) 1972-11-15

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