ES432404A1 - Procedimiento de obtencion de un activador del plasminoge- no. - Google Patents
Procedimiento de obtencion de un activador del plasminoge- no.Info
- Publication number
- ES432404A1 ES432404A1 ES432404A ES432404A ES432404A1 ES 432404 A1 ES432404 A1 ES 432404A1 ES 432404 A ES432404 A ES 432404A ES 432404 A ES432404 A ES 432404A ES 432404 A1 ES432404 A1 ES 432404A1
- Authority
- ES
- Spain
- Prior art keywords
- solution
- taking
- approximately
- comprised
- precipitate obtained
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 102000001938 Plasminogen Activators Human genes 0.000 title abstract 2
- 108010001014 Plasminogen Activators Proteins 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 229940127126 plasminogen activator Drugs 0.000 title abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 3
- 239000002244 precipitate Substances 0.000 abstract 3
- 239000000243 solution Substances 0.000 abstract 3
- 241000282887 Suidae Species 0.000 abstract 2
- 239000000843 powder Substances 0.000 abstract 2
- 238000001556 precipitation Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 244000003363 Allium ursinum Species 0.000 abstract 1
- 241000283725 Bos Species 0.000 abstract 1
- 241000283690 Bos taurus Species 0.000 abstract 1
- 241000283086 Equidae Species 0.000 abstract 1
- 241000283903 Ovis aries Species 0.000 abstract 1
- 241001494479 Pecora Species 0.000 abstract 1
- 210000001557 animal structure Anatomy 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 244000309466 calf Species 0.000 abstract 1
- 238000010908 decantation Methods 0.000 abstract 1
- 238000000502 dialysis Methods 0.000 abstract 1
- 210000003734 kidney Anatomy 0.000 abstract 1
- 210000004072 lung Anatomy 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 210000001672 ovary Anatomy 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Feed For Specific Animals (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7342981A FR2252842B1 (enExample) | 1973-12-03 | 1973-12-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES432404A1 true ES432404A1 (es) | 1976-11-16 |
Family
ID=9128602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES432404A Expired ES432404A1 (es) | 1973-12-03 | 1974-11-28 | Procedimiento de obtencion de un activador del plasminoge- no. |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE822531A (enExample) |
| DE (1) | DE2456589C2 (enExample) |
| ES (1) | ES432404A1 (enExample) |
| FR (1) | FR2252842B1 (enExample) |
| GB (1) | GB1492959A (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2121050B (en) * | 1979-07-05 | 1986-03-26 | Genentech Inc | Preparation of functional human urokinase proteins |
| CA1154671A (fr) * | 1979-07-27 | 1983-10-04 | Lucien D. D'hinterland | Separation d'un activateur tissulaire du plasminogene |
| FR2483234A2 (fr) * | 1980-05-29 | 1981-12-04 | Fabre Sa Pierre | Composition ophtalmique contenant un activateur du plasminogene |
| NL8003402A (nl) * | 1980-06-11 | 1982-01-04 | Leuven Res & Dev Vzw | Nieuwe plasminogeen-activator en farmaceutisch preparaat met trombolytische werking. |
| US5112755A (en) * | 1982-04-15 | 1992-05-12 | Genentech, Inc. | Preparation of functional human urokinase proteins |
| FI831484A7 (fi) * | 1982-05-05 | 1983-11-06 | Genentech Inc | Ihmiskudoksen plasminogeenien aktivaattori. |
| US4766075A (en) * | 1982-07-14 | 1988-08-23 | Genentech, Inc. | Human tissue plasminogen activator |
| US5185259A (en) * | 1982-05-05 | 1993-02-09 | Genentech, Inc. | Truncated human tissue plasminogen activator |
| GT198302091A (es) * | 1982-05-05 | 1984-10-25 | Activador de plasminogeno de tejido humano a),b),c). | |
| US4853330A (en) * | 1983-04-07 | 1989-08-01 | Genentech, Inc. | Human tissue plasminogen activator |
| IL68561A (en) * | 1982-05-05 | 1991-01-31 | Genentech Inc | Preparation of polypeptide with human tissue plasminogen activator function,processes for making it,and dna and transformed cell intermediates thereof |
| FR2593393B1 (fr) * | 1985-05-28 | 1989-06-02 | Wellcome Found | Solution aqueuse a usage parenteral d'activateur tissulaire du plasminogene, procede pour la preparer et recipient obture la contenant |
| US4929444A (en) * | 1985-05-28 | 1990-05-29 | Burroughs Wellcome Co. | Low pH pharmaceutical formulation containing t-PA |
-
1973
- 1973-12-03 FR FR7342981A patent/FR2252842B1/fr not_active Expired
-
1974
- 1974-11-22 BE BE150798A patent/BE822531A/xx not_active IP Right Cessation
- 1974-11-28 ES ES432404A patent/ES432404A1/es not_active Expired
- 1974-11-29 DE DE19742456589 patent/DE2456589C2/de not_active Expired
- 1974-12-03 GB GB5221674A patent/GB1492959A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB1492959A (en) | 1977-11-23 |
| DE2456589A1 (de) | 1975-06-05 |
| DE2456589C2 (de) | 1983-12-29 |
| FR2252842A1 (enExample) | 1975-06-27 |
| BE822531A (fr) | 1975-03-14 |
| FR2252842B1 (enExample) | 1977-11-04 |
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