ES432218A1 - Phenylalkenoic acid derivatives - Google Patents
Phenylalkenoic acid derivativesInfo
- Publication number
- ES432218A1 ES432218A1 ES432218A ES432218A ES432218A1 ES 432218 A1 ES432218 A1 ES 432218A1 ES 432218 A ES432218 A ES 432218A ES 432218 A ES432218 A ES 432218A ES 432218 A1 ES432218 A1 ES 432218A1
- Authority
- ES
- Spain
- Prior art keywords
- radical
- general formula
- acids
- butenoic
- transformed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/08—Compounds containing oxirane rings with hydrocarbon radicals, substituted by halogen atoms, nitro radicals or nitroso radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/58—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Procedure for the preparation of new derivatives of 3-butenoic and 2-butenoic acids of the general formula I ** (See formula) ** wherein the R1 radical means a branched or unbranched alcohol radical with 1 to 7 carbon atoms, a 5-, 6- or 7-membered cycloalkyl or cycloalkenyl radical, the piperidino radical or a phenyl radical, which may optionally be substituted by one or two halogen atoms, or an amino group possibly substituted by an aliphatic acyl radical with 1 to 4 carbon atoms, the radical R3 means a hydrogen atom, a halogen atom or, if R1 has the meanings indicated above with Except for that of an optionally substituted phenyl radical, it represents an amino group, provided that R3 does not mean any hydrogen atom when R1 represents an unsubstituted phenyl radical, and radical 8 represents the hydroxy group, an alkoxy radical with 1 to 4 carbon atoms or a radical of the general formula II, ** (See formula) ** in which R4 and R5, which may be the same or different, represent hydrogen atoms, or, in case R1 means an optionally substituted phenyl radical as defined above, they also represent alcohol radicals with 1 to 3 carbon atoms, where R4 may in this case also be a hydroxyphenyl radical when R5 represents a hydrogen atom and radical A represents bivalent radicals (see formula) or CH2-CH = CH, as well as, if B is the hydroxy group, its salts are physiologically compatible with organic or inorganic bases and, if R1 contains a basic radical or R3 means a basic group, of its physiologically compatible salts with organic or inorganic acids, characterized in that a mixture of 2-butenoic and 3-butenoic acids obtained is subsequently separated, if desired, by physical methods into the 2-butenoic and 3-butenoic acids of the general formula I and optionally at the same time separating into the cis and trans isomers of these acids, and/or compounds obtained from the general formula I, in which B is the hydroxy group, are transformed, if desired, into compounds of the general formula I, where B represents an alkoxy group, and/or compounds of the general formula I, where B represents a halogen atom or an alkoxy group, are transformed with an amine of the general formula IV. ** (See formula) ** in the amides of the general formula I, and/or if desired acids of the general formula I are transformed with organic or inorganic bases in their salts, and the compounds of the general formula I, in which R1 contains a basic radical or R3 basic radicals are transformed, if desired, into their salts by adding acid with organic or inorganic acids. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2205732A DE2205732A1 (en) | 1972-02-08 | 1972-02-08 | NEW 4- (4-BIPHENYLYL) -BUTIC ACID DERIVATIVES |
DE19722223562 DE2223562A1 (en) | 1972-05-15 | 1972-05-15 | NEW BUTENIC ACIDS, THEIR SALT AND DERIVATIVES AND THE PROCESS FOR THEIR PRODUCTION |
Publications (1)
Publication Number | Publication Date |
---|---|
ES432218A1 true ES432218A1 (en) | 1976-11-01 |
Family
ID=25762690
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES432218A Expired ES432218A1 (en) | 1972-02-08 | 1974-11-23 | Phenylalkenoic acid derivatives |
ES432220A Expired ES432220A1 (en) | 1972-02-08 | 1974-11-23 | Phenylalkenoic acid derivatives |
ES432219A Expired ES432219A1 (en) | 1972-02-08 | 1974-11-23 | Phenylalkenoic acid derivatives |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES432220A Expired ES432220A1 (en) | 1972-02-08 | 1974-11-23 | Phenylalkenoic acid derivatives |
ES432219A Expired ES432219A1 (en) | 1972-02-08 | 1974-11-23 | Phenylalkenoic acid derivatives |
Country Status (13)
Country | Link |
---|---|
JP (1) | JPS4891032A (en) |
AT (3) | AT325025B (en) |
BE (1) | BE795159A (en) |
BG (1) | BG21391A3 (en) |
CA (1) | CA978967A (en) |
DD (1) | DD107898A5 (en) |
ES (3) | ES432218A1 (en) |
GB (1) | GB1413042A (en) |
HU (1) | HU165625B (en) |
IL (1) | IL41484A0 (en) |
NL (1) | NL7301631A (en) |
SU (1) | SU526285A3 (en) |
ZA (1) | ZA73851B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR68102B (en) * | 1978-08-08 | 1981-10-30 | Fujisawa Pharmaceutical Co |
-
0
- BE BE795159D patent/BE795159A/en unknown
-
1973
- 1973-01-29 AT AT73673A patent/AT325025B/en not_active IP Right Cessation
- 1973-01-29 AT AT311474A patent/AT325026B/en not_active IP Right Cessation
- 1973-01-29 AT AT311374*7A patent/AT326640B/en not_active IP Right Cessation
- 1973-02-06 HU HUTO897A patent/HU165625B/hu unknown
- 1973-02-06 NL NL7301631A patent/NL7301631A/xx unknown
- 1973-02-06 BG BG26954A patent/BG21391A3/xx unknown
- 1973-02-07 CA CA163,115A patent/CA978967A/en not_active Expired
- 1973-02-07 JP JP48015456A patent/JPS4891032A/ja active Pending
- 1973-02-07 ZA ZA730851A patent/ZA73851B/en unknown
- 1973-02-07 GB GB607173A patent/GB1413042A/en not_active Expired
- 1973-02-07 IL IL41484A patent/IL41484A0/en unknown
- 1973-02-08 DD DD168763A patent/DD107898A5/en unknown
-
1974
- 1974-02-13 SU SU1995309A patent/SU526285A3/en active
- 1974-11-23 ES ES432218A patent/ES432218A1/en not_active Expired
- 1974-11-23 ES ES432220A patent/ES432220A1/en not_active Expired
- 1974-11-23 ES ES432219A patent/ES432219A1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
BG21391A3 (en) | 1976-05-20 |
AT325025B (en) | 1975-09-25 |
BE795159A (en) | 1973-08-08 |
ZA73851B (en) | 1974-10-30 |
AT326640B (en) | 1975-12-29 |
ATA311374A (en) | 1975-03-15 |
CA978967A (en) | 1975-12-02 |
DD107898A5 (en) | 1974-08-20 |
IL41484A0 (en) | 1973-04-30 |
SU526285A3 (en) | 1976-08-25 |
ES432219A1 (en) | 1976-11-01 |
HU165625B (en) | 1974-09-28 |
JPS4891032A (en) | 1973-11-27 |
GB1413042A (en) | 1975-11-05 |
AT325026B (en) | 1975-09-25 |
NL7301631A (en) | 1973-08-10 |
ES432220A1 (en) | 1976-11-01 |
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