ES345784A1 - Procedure for the preparation of 3-substitute 1-oxo-isoindolins and 1-oxo-isoindolines 2,3-substitute. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of 3-substitute 1-oxo-isoindolins and 1-oxo-isoindolines 2,3-substitute. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES345784A1 ES345784A1 ES345784A ES345784A ES345784A1 ES 345784 A1 ES345784 A1 ES 345784A1 ES 345784 A ES345784 A ES 345784A ES 345784 A ES345784 A ES 345784A ES 345784 A1 ES345784 A1 ES 345784A1
- Authority
- ES
- Spain
- Prior art keywords
- oxo
- substitute
- isoindolines
- alkyl
- translation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- PXZQEOJJUGGUIB-UHFFFAOYSA-N isoindolin-1-one Chemical class C1=CC=C2C(=O)NCC2=C1 PXZQEOJJUGGUIB-UHFFFAOYSA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- -1 3-substituted 1-oxo-isoindolines Chemical class 0.000 abstract 1
- XXYNZSATHOXXBJ-UHFFFAOYSA-N 4-hydroxyisoindole-1,3-dione Chemical class OC1=CC=CC2=C1C(=O)NC2=O XXYNZSATHOXXBJ-UHFFFAOYSA-N 0.000 abstract 1
- 125000005119 alkyl cycloalkyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000005343 heterocyclic alkyl group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedure for the preparation of 3-substituted 1-oxo-isoindolines and 2,3-substituted 1-oxo-isoindolines, having the following formula (I) and their salts with physiologically appropriate organic and inorganic acids: **(See formula)** in which X = H, Cl, Oralkyl, CH3, OH X = H, branched or unbranched (C1-C6) alkyl, aryl alkyl, alkylcycloalkyl, heterocyclic alkyl **(See formula)** with n = 2 - 6 R1 = H, alkyl branched or not R2 = or different from R3 and alkyl the same branched or not or belonging to a heterocyclic ring Z = O, S characterized in that the substituted or unsubstituted 3-hydroxyphthalimide is condensed with amines according to formula (II): **(See formula)** in which R1, R2, R3 and Z have the meanings mentioned above, and the products thus obtained are eventually rented. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2277166 | 1966-09-23 | ||
| IT3181866A IT1053667B (en) | 1966-12-31 | 1966-12-31 | Compounds of formula (I) and acid addition salts thereof. X = H, Cl, alkoxy, CH3, OH Y = H, alkyl, aralkyl, alkylcycloalkyl, alkylheterocyclic |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES345784A1 true ES345784A1 (en) | 1969-02-01 |
Family
ID=26328264
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES345784A Expired ES345784A1 (en) | 1966-09-23 | 1967-09-22 | Procedure for the preparation of 3-substitute 1-oxo-isoindolins and 1-oxo-isoindolines 2,3-substitute. (Machine-translation by Google Translate, not legally binding) |
Country Status (4)
| Country | Link |
|---|---|
| ES (1) | ES345784A1 (en) |
| FI (1) | FI51482C (en) |
| GR (1) | GR37267B (en) |
| SE (1) | SE313054B (en) |
-
1967
- 1967-09-22 SE SE13036/67A patent/SE313054B/xx unknown
- 1967-09-22 GR GR670137267A patent/GR37267B/en unknown
- 1967-09-22 ES ES345784A patent/ES345784A1/en not_active Expired
- 1967-09-25 FI FI672547A patent/FI51482C/en active
Also Published As
| Publication number | Publication date |
|---|---|
| FI51482B (en) | 1976-09-30 |
| FI51482C (en) | 1977-01-10 |
| SE313054B (en) | 1969-08-04 |
| GR37267B (en) | 1969-05-12 |
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