ES424859A1 - Procedimiento para la obtencion de derivados de 2-arilamino-2-imidazolina. - Google Patents
Procedimiento para la obtencion de derivados de 2-arilamino-2-imidazolina.Info
- Publication number
- ES424859A1 ES424859A1 ES74424859A ES424859A ES424859A1 ES 424859 A1 ES424859 A1 ES 424859A1 ES 74424859 A ES74424859 A ES 74424859A ES 424859 A ES424859 A ES 424859A ES 424859 A1 ES424859 A1 ES 424859A1
- Authority
- ES
- Spain
- Prior art keywords
- arylamino
- imidazoline
- salts
- manufacture
- imidazoline derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N N-phenyl amine Natural products NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 abstract 1
- 125000002490 anilino group Chemical class [H]N(*)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 238000006386 neutralization reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
- C07D233/38—One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2316377A DE2316377C3 (de) | 1973-04-02 | 1973-04-02 | Verfahren zur Herstellung von 2-Phenyl-amino-2-imidazolin-Derivaten und von deren Salzen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES424859A1 true ES424859A1 (es) | 1976-06-01 |
Family
ID=5876755
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES74424859A Expired ES424859A1 (es) | 1973-04-02 | 1974-04-02 | Procedimiento para la obtencion de derivados de 2-arilamino-2-imidazolina. |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US3931216A (en, 2012) |
| JP (1) | JPS528833B2 (en, 2012) |
| BE (1) | BE813144A (en, 2012) |
| BG (1) | BG27898A3 (en, 2012) |
| CA (1) | CA1009239A (en, 2012) |
| CH (1) | CH583708A5 (en, 2012) |
| CS (1) | CS176134B2 (en, 2012) |
| DD (1) | DD110495A1 (en, 2012) |
| DE (1) | DE2316377C3 (en, 2012) |
| DK (1) | DK145907C (en, 2012) |
| ES (1) | ES424859A1 (en, 2012) |
| FI (1) | FI59991C (en, 2012) |
| FR (1) | FR2223365B1 (en, 2012) |
| GB (1) | GB1450250A (en, 2012) |
| HU (1) | HU169498B (en, 2012) |
| NL (1) | NL167424C (en, 2012) |
| NO (1) | NO741170L (en, 2012) |
| PL (1) | PL88699B1 (en, 2012) |
| RO (1) | RO63906A (en, 2012) |
| SE (1) | SE405970B (en, 2012) |
| SU (1) | SU511000A3 (en, 2012) |
| YU (1) | YU36931B (en, 2012) |
| ZA (2) | ZA741910B (en, 2012) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT330769B (de) * | 1974-04-05 | 1976-07-26 | Chemie Linz Ag | Verfahren zur herstellung von 2-arylamino- 2-imidazolin-derivaten und ihren salzen |
| US4125620A (en) * | 1974-10-01 | 1978-11-14 | Boehringer Ingelheim Gmbh | 2-[(2',6'-Disubstituted-phenyl)-imino]-imidazolidines and salts thereof |
| DE2652004C3 (de) * | 1976-11-15 | 1979-09-13 | Basf Ag, 6700 Ludwigshafen | l-Acyl-2-arylamino-2-imidazoline, Verfahren zu ihrer Herstellung und ihre Verwendung |
| NL7711390A (nl) * | 1977-10-18 | 1979-04-20 | Philips Nv | Nieuwe 2-arylimino-hexahydopyrimidinen en - imi- dazolidinen, zouten en complexen daarvan, werk- wijze ter bereiding van de nieuwe verbindingen, alsmede fungicide preparaten op basis van de nieuwe verbindingen. |
| DE2811847A1 (de) * | 1978-03-17 | 1979-09-20 | Lentia Gmbh | Neue arylaminoimidazolinderivate, deren herstellung und verwendung als arzneimittel |
| US4515800A (en) * | 1981-11-20 | 1985-05-07 | Icilio Cavero | Method of lowering intraocular pressure using phenylimino-imidazoles |
| US4461904A (en) * | 1981-11-20 | 1984-07-24 | Alcon Laboratories, Inc. | 2-(Trisubstituted phenylimino)-imidazolines |
| US4517199A (en) * | 1981-11-20 | 1985-05-14 | Alcon Laboratories, Inc. | Method for lowering intraocular pressure using phenylimino-imidazoles |
| US4644007A (en) * | 1981-11-20 | 1987-02-17 | Alcon Laboratories, Inc. | 3-chloro-4-(4,5-dihydro-1H-imidazo-2-yl)-amino-5-alkylbenzoic acids, esters, salts, compositions and methods |
| HU192986B (en) | 1984-05-23 | 1987-08-28 | Egyt Gyogyszervegyeszeti Gyar | Process for production of imidasodiline derivatives |
| DE19514579A1 (de) | 1995-04-20 | 1996-10-24 | Boehringer Ingelheim Kg | Verwendung von alpha¶1¶¶L¶-Agonisten zur Behandlung der Harninkontinenz |
| UA39128C2 (uk) * | 1996-06-11 | 2001-06-15 | Спільне Українсько-Бельгійське Хімічне Підприємство "Інтерхім" | Спосіб одержання 2-(2,6-дихлорфеніламіно)-2-імідазоліну гідрохлориду |
| US6184242B1 (en) | 1997-09-04 | 2001-02-06 | Syntex Usa (Llc) | 2-(substituted-phenyl)amino-imidazoline derivatives |
| US6417186B1 (en) | 2000-11-14 | 2002-07-09 | Syntex (U.S.A.) Llc | Substituted-phenyl ketone derivatives as IP antagonists |
| CA2981732C (en) * | 2015-04-07 | 2024-03-12 | Boris Khalfin | Compositions for treating and/or preventing cell or tissue necrosis specifically targeting cathepsin c and/or cela1 and/or cela3a and/or structurally related enzymes thereto |
| RU2652125C1 (ru) * | 2017-10-02 | 2018-04-25 | Акционерное общество "Федеральный научно-производственный центр "Алтай" | Способ получения 2-(2,6-дихлорфениламино)-2-имидазолина гидрохлорида |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2899426A (en) * | 1959-08-11 | Synthesis of l | ||
| US3236857A (en) * | 1961-10-09 | 1966-02-22 | Boehringer Sohn Ingelheim | 2-(phenyl-amino)-1, 3-diazacyclopentene-(2) substitution products |
| US3595961A (en) * | 1965-10-01 | 1971-07-27 | Boehringer Sohn Ingelheim | Hypotensive compositions containing 2-(2' - halo-anilino) - 1,3 -diazacyclopentenes-(2) and methods of using the same |
| DE1545628A1 (de) * | 1965-10-01 | 1970-06-25 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung von blutdrucksenkend und sedativ wirksamen Derivaten des 2-(2-Halogenanilino)-1,3-diazacyclopentens-(2) |
| BE759048A (fr) * | 1969-11-17 | 1971-05-17 | Boehringer Sohn Ingelheim | Nouvelles n-aminoalcoyl-arylamino-imidazolines-(2) substituees et procedes pour les fabriquer |
-
1973
- 1973-04-02 DE DE2316377A patent/DE2316377C3/de not_active Expired
-
1974
- 1974-03-15 HU HUCE992A patent/HU169498B/hu not_active IP Right Cessation
- 1974-03-19 DK DK149874A patent/DK145907C/da not_active IP Right Cessation
- 1974-03-21 FI FI856/74A patent/FI59991C/fi active
- 1974-03-22 GB GB1293474A patent/GB1450250A/en not_active Expired
- 1974-03-25 ZA ZA00741910A patent/ZA741910B/xx unknown
- 1974-03-26 SE SE7404043A patent/SE405970B/xx not_active IP Right Cessation
- 1974-03-27 FR FR7410468A patent/FR2223365B1/fr not_active Expired
- 1974-03-27 CH CH423874A patent/CH583708A5/xx not_active IP Right Cessation
- 1974-03-29 US US05/456,200 patent/US3931216A/en not_active Expired - Lifetime
- 1974-03-29 DD DD177562A patent/DD110495A1/xx unknown
- 1974-03-29 YU YU0881/74A patent/YU36931B/xx unknown
- 1974-03-30 BG BG026251A patent/BG27898A3/xx unknown
- 1974-04-01 PL PL1974170011A patent/PL88699B1/pl unknown
- 1974-04-01 NO NO741170A patent/NO741170L/no unknown
- 1974-04-01 CS CS2337A patent/CS176134B2/cs unknown
- 1974-04-01 BE BE142717A patent/BE813144A/xx not_active IP Right Cessation
- 1974-04-01 ZA ZA00742061A patent/ZA742061B/xx unknown
- 1974-04-02 SU SU2011368A patent/SU511000A3/ru active
- 1974-04-02 RO RO7478275A patent/RO63906A/ro unknown
- 1974-04-02 JP JP49036690A patent/JPS528833B2/ja not_active Expired
- 1974-04-02 ES ES74424859A patent/ES424859A1/es not_active Expired
- 1974-04-02 NL NL7404472.A patent/NL167424C/xx not_active IP Right Cessation
- 1974-04-02 CA CA196,643A patent/CA1009239A/en not_active Expired
Also Published As
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