ES386685A1 - Un procedimiento para preparar derivados benzodiacepinicos. - Google Patents
Un procedimiento para preparar derivados benzodiacepinicos.Info
- Publication number
- ES386685A1 ES386685A1 ES386685A ES386685A ES386685A1 ES 386685 A1 ES386685 A1 ES 386685A1 ES 386685 A ES386685 A ES 386685A ES 386685 A ES386685 A ES 386685A ES 386685 A1 ES386685 A1 ES 386685A1
- Authority
- ES
- Spain
- Prior art keywords
- compound
- formula
- well
- same meaning
- general formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000008366 benzophenones Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 18
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000004471 Glycine Substances 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 238000005903 acid hydrolysis reaction Methods 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229940053197 benzodiazepine derivative antiepileptics Drugs 0.000 abstract 1
- 125000003310 benzodiazepinyl group Chemical class N1N=C(C=CC2=C1C=CC=C2)* 0.000 abstract 1
- 230000000911 decarboxylating effect Effects 0.000 abstract 1
- 239000012954 diazonium Substances 0.000 abstract 1
- 150000001989 diazonium salts Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 230000001035 methylating effect Effects 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
- C07D243/28—Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4253370A | 1970-06-01 | 1970-06-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES386685A1 true ES386685A1 (es) | 1973-03-16 |
Family
ID=21922438
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES386685A Expired ES386685A1 (es) | 1970-06-01 | 1970-12-21 | Un procedimiento para preparar derivados benzodiacepinicos. |
Country Status (15)
Country | Link |
---|---|
AR (1) | AR193050A1 (es) |
BE (1) | BE760510A (es) |
BG (3) | BG18186A3 (es) |
CH (2) | CH561684A5 (es) |
DE (1) | DE2062927A1 (es) |
DK (1) | DK136647B (es) |
ES (1) | ES386685A1 (es) |
FR (1) | FR2093923B1 (es) |
GB (1) | GB1332699A (es) |
IE (1) | IE35428B1 (es) |
IL (1) | IL35885A (es) |
NL (1) | NL7018577A (es) |
NO (1) | NO130681C (es) |
PH (1) | PH9829A (es) |
SE (2) | SE385298B (es) |
-
1970
- 1970-12-11 CH CH1745473A patent/CH561684A5/xx not_active IP Right Cessation
- 1970-12-11 CH CH1838170A patent/CH549586A/xx not_active IP Right Cessation
- 1970-12-18 BE BE760510A patent/BE760510A/xx unknown
- 1970-12-21 BG BG019454A patent/BG18186A3/xx unknown
- 1970-12-21 ES ES386685A patent/ES386685A1/es not_active Expired
- 1970-12-21 NO NO4888/70A patent/NO130681C/no unknown
- 1970-12-21 DE DE19702062927 patent/DE2062927A1/de not_active Ceased
- 1970-12-21 GB GB1229172A patent/GB1332699A/en not_active Expired
- 1970-12-21 NL NL7018577A patent/NL7018577A/xx not_active Application Discontinuation
- 1970-12-21 SE SE7017330A patent/SE385298B/xx unknown
- 1970-12-21 PH PH12060A patent/PH9829A/en unknown
- 1970-12-21 FR FR7046020A patent/FR2093923B1/fr not_active Expired
- 1970-12-21 IL IL35885A patent/IL35885A/xx unknown
- 1970-12-21 DK DK649370AA patent/DK136647B/da unknown
- 1970-12-21 BG BG019457A patent/BG18188A3/xx unknown
- 1970-12-21 IE IE1624/70A patent/IE35428B1/xx unknown
- 1970-12-21 BG BG019455A patent/BG18187A3/xx unknown
-
1971
- 1971-10-04 AR AR238272A patent/AR193050A1/es active
-
1975
- 1975-11-26 SE SE7513327A patent/SE7513327L/xx unknown
Also Published As
Publication number | Publication date |
---|---|
NL7018577A (es) | 1971-12-03 |
GB1332699A (en) | 1973-10-03 |
SE385298B (sv) | 1976-06-21 |
AR193050A1 (es) | 1973-03-30 |
NO130681C (es) | 1975-01-22 |
BG18186A3 (bg) | 1974-09-02 |
CH549586A (de) | 1974-05-31 |
CH561684A5 (es) | 1975-05-15 |
FR2093923B1 (es) | 1974-05-24 |
IL35885A (en) | 1974-05-16 |
SE7513327L (sv) | 1975-11-26 |
DK136647C (es) | 1978-04-17 |
BE760510A (fr) | 1971-06-18 |
BG18188A3 (bg) | 1974-09-02 |
IE35428L (en) | 1971-12-01 |
DE2062927A1 (de) | 1971-12-16 |
BG18187A3 (bg) | 1974-09-02 |
IE35428B1 (en) | 1976-02-18 |
FR2093923A1 (es) | 1972-02-04 |
PH9829A (en) | 1976-04-02 |
DK136647B (da) | 1977-11-07 |
IL35885A0 (en) | 1971-04-28 |
NO130681B (es) | 1974-10-14 |
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