CH609665A5 - Process for the preparation of indan- and tetrahydronaphthalene carboxylic acids - Google Patents

Process for the preparation of indan- and tetrahydronaphthalene carboxylic acids

Info

Publication number
CH609665A5
CH609665A5 CH1089674A CH1089674A CH609665A5 CH 609665 A5 CH609665 A5 CH 609665A5 CH 1089674 A CH1089674 A CH 1089674A CH 1089674 A CH1089674 A CH 1089674A CH 609665 A5 CH609665 A5 CH 609665A5
Authority
CH
Switzerland
Prior art keywords
carboxylic acids
indan
preparation
tetrahydronaphthalene
tetrahydronaphthalene carboxylic
Prior art date
Application number
CH1089674A
Inventor
Shunsaku Noguchi
Tetsuya Aono
Yoshiaki Araki
Kiyohisa Kawai
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP9837173A external-priority patent/JPS5613703B2/ja
Priority claimed from JP10360573A external-priority patent/JPS5817742B2/en
Priority claimed from JP10360673A external-priority patent/JPS5710870B2/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of CH609665A5 publication Critical patent/CH609665A5/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C07D453/04—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems having a quinolyl-4, a substituted quinolyl-4 or a alkylenedioxy-quinolyl-4 radical linked through only one carbon atom, attached in position 2, e.g. quinine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/28—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of CHx-moieties
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/657—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
    • C07C49/665—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system
    • C07C49/67—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system having two rings, e.g. tetralones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
    • C07C49/697—Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • C07C49/755—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/782—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic
    • C07C49/792—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Compounds of the formula: <IMAGE> in which R<1> is an unsubstituted or substituted aryl group and n is 1 or 2, are prepared by hydrolysing corresponding 1-cyanoindanes and 1-cyano-1,2,3,4-tetrahydronaphthalines. The carboxylic acids and their salts have analgesic, antipyretic and antiinflammatory properties and can be used for corresponding therapeutic indications.
CH1089674A 1973-09-01 1974-08-09 Process for the preparation of indan- and tetrahydronaphthalene carboxylic acids CH609665A5 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP9837173A JPS5613703B2 (en) 1973-09-01 1973-09-01
JP10360573A JPS5817742B2 (en) 1973-09-13 1973-09-13 Kanjiyouka Gobutsuno Seizouhou
JP10360673A JPS5710870B2 (en) 1973-09-13 1973-09-13

Publications (1)

Publication Number Publication Date
CH609665A5 true CH609665A5 (en) 1979-03-15

Family

ID=27308650

Family Applications (2)

Application Number Title Priority Date Filing Date
CH984277A CH607991A5 (en) 1973-09-01 1974-08-09 Process for the preparation of benzalicyclic compounds
CH1089674A CH609665A5 (en) 1973-09-01 1974-08-09 Process for the preparation of indan- and tetrahydronaphthalene carboxylic acids

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH984277A CH607991A5 (en) 1973-09-01 1974-08-09 Process for the preparation of benzalicyclic compounds

Country Status (1)

Country Link
CH (2) CH607991A5 (en)

Also Published As

Publication number Publication date
CH607991A5 (en) 1978-12-15

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Legal Events

Date Code Title Description
PL Patent ceased